A high-resolution map of human evolutionary constraint using 29 mammals

K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker… - Nature, 2011 - nature.com
The comparison of related genomes has emerged as a powerful lens for genome
interpretation. Here we report the sequencing and comparative analysis of 29 eutherian …

Comparative and demographic analysis of orang-utan genomes

DP Locke, LDW Hillier, WC Warren, KC Worley… - Nature, 2011 - nature.com
Abstract 'Orang-utan'is derived from a Malay term meaning 'man of the forest'and aptly
describes the southeast Asian great apes native to Sumatra and Borneo. The orang-utan …

Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers

LJ Core, AL Martins, CG Danko, CT Waters, A Siepel… - Nature …, 2014 - nature.com
Despite the conventional distinction between them, promoters and enhancers share many
features in mammals, including divergent transcription and similar modes of transcription …

[PDF][PDF] Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells

CG Danko, N Hah, X Luo, AL Martins, L Core, JT Lis… - Molecular cell, 2013 - cell.com
Summary RNA polymerase II (Pol II) transcribes hundreds of kilobases of DNA, limiting the
production of mRNAs and lncRNAs. We used global run-on sequencing (GRO-seq) to …

The effect of drillpipe rotation on hole cleaning during directional well drilling

RA Sanchez, JJ Azar, AA Bassal… - SPE/IADC Drilling …, 1997 - onepetro.org
The effect of drillpipe rotation on hole cleaning during directional well drilling is investigated.
An 8" diameter wellbore simulator, 100 ft long, with a 4 1/2" drillpipe was used for the study …

Identification of active transcriptional regulatory elements from GRO-seq data

CG Danko, SL Hyland, LJ Core, AL Martins… - Nature …, 2015 - nature.com
Modifications to the global run-on and sequencing (GRO-seq) protocol that enrich for 5′-
capped RNAs can be used to reveal active transcriptional regulatory elements (TREs) with …

Are there multiple bubbles in the ethanol–gasoline price ratio of Brazil?

G El Montasser, R Gupta, AL Martins… - … and Sustainable Energy …, 2015 - Elsevier
This paper tests for the existence of bubbles in the ethanol–gasoline price ratio in Brazil from
2000 to 2012 using right-tailed ADF tests. Results suggest the existence of two bubbles: one …

GAGA factor maintains nucleosome-free regions and has a role in RNA polymerase II recruitment to promoters

NJ Fuda, MJ Guertin, S Sharma, CG Danko… - PLoS …, 2015 - journals.plos.org
Previous studies have shown that GAGA Factor (GAF) is enriched on promoters with paused
RNA Polymerase II (Pol II), but its genome-wide function and mechanism of action remain …

Effect of storage time on bond strength and nanoleakage expression of universal adhesives bonded to dentin and etched enamel

P Makishi, CB André, APA Ayres… - Operative …, 2016 - meridian.allenpress.com
Purpose: To investigate bond strength and nanoleakage expression of universal adhesives
(UA) bonded to dentin and etched enamel. Methods: Extracted human third molars were …

Testing the boundaries of lean thinking: observations from the legal public sector

P Hines, AL Martins, J Beale - Public money and management, 2008 - Taylor & Francis
This article explores how Lean Thinking can be successfully extended into the legal sector,
which in most advanced economies is dominated by the public sector. Two public sector …