Macrophage type-I and type-II class-A scavenger receptors (MSR-A) are implicated in the
pathological deposition of cholesterol during atherogenesis as a result of receptor-mediated …

CLONAL deletion and functional inactivation of self-reactive cells have been invoked as
mechanisms underlying intrathymic development of T-cell tolerance1–10. The relative …

The tuberculin skin test for immunologic diagnosis of Mycobacterium tuberculosis infection
has many limitations, including being confounded by bacillus Calmette-Guérin (BCG) …

Background. Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus
(SFTSV), a novel bunyavirus reported to be endemic in central and northeastern China. This …

Aggregative multicellularity, resulting in formation of a spore-bearing fruiting body, evolved
at least six times independently amongst both eukaryotes and prokaryotes. Amongst …

In skeletal muscle, asymmetrically dividing satellite stem cells give rise to committed satellite
cells that transcribe the myogenic determination factor Myf5, a Pax7-target gene. We …

For many antibodies, each antigen-binding site binds to only one antigen molecule during
the antibody's lifetime in plasma. To increase the number of cycles of antigen binding and …

DNA demethylation plays a critical role in transcriptional regulation in differentiated somatic
cells. However, there is no experimental evidence that CpG methylation in a small region of …

The electron injection process, which limits the electroluminescent performance of organic
devices, has been enhanced tremendously by inserting a layer of LiF with appropriate …

Hemophilia A is a bleeding disorder resulting from coagulation factor VIII (FVIII) deficiency.
Exogenously provided FVIII effectively reduces bleeding complications in patients with …