User profiles for "author:Kaji K"

Keisuke Kaji - Verified email at ed.ac.uk - Cited by 8379
Koichi Kaji - Verified email at cc.tuat.ac.jp - Cited by 3880
Kosuke Kaji - Verified email at naramed-u.ac.jp - Cited by 3550

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

K Kaji, K Norrby, A Paca, M Mileikovsky, P Mohseni… - Nature, 2009 - nature.com
Reprogramming of somatic cells to pluripotency, thereby creating induced pluripotent stem
(iPS) cells, promises to transform regenerative medicine. Most instances of direct …

The mechanism of sperm–oocyte fusion in mammals

K Kaji, A Kudo - Reproduction, 2004 - rep.bioscientifica.com
Sperm–oocyte fusion is one of the most impressive events in sexual reproduction, and the
elucidation of its molecular mechanism has fascinated researchers for a long time. Because …

Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy

K Kaji, M Fujimoto, M Hasegawa, M Kondo… - …, 2007 - academic.oup.com
Abstract Objective. Myositis-specific autoantibodies (MSAs) are a useful tool in diagnosis,
defining clinical subsets and predicting prognosis of dermatomyositis (DM) and polymyositis …

Adaptive management of sika deer populations in Hokkaido, Japan: theory and practice

K Kaji, T Saitoh, H Uno, H Matsuda, K Yamamura - Population Ecology, 2010 - Springer
We investigated the utility of adaptive management (AM) in wildlife management, reviewing
our experiences in applying AM to overabundant sika deer (Cervus nippon) populations in …

The gamete fusion process is defective in eggs of Cd9-deficient mice

K Kaji, S Oda, T Shikano, T Ohnuki, Y Uematsu… - Nature …, 2000 - nature.com
The cell-surface molecule Cd9, a member of the transmembrane-4 superfamily 1, interacts
with the integrin family 2 and other membrane proteins 3, 4, 5, and is postulated to …

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

K Woltjen, IP Michael, P Mohseni, R Desai… - nature, 2009 - nature.com
Transgenic expression of just four defined transcription factors (c-Myc, Klf4, Oct4 and Sox2)
is sufficient to reprogram somatic cells to a pluripotent state,,,. The resulting induced …

Spinodal crystallization of polymers: Crystallization from the unstable melt

K Kaji, K Nishida, T Kanaya, G Matsuba… - … and mesophases in …, 2005 - Springer
This paper reviews the authors' investigation into polymer crystallization, especially
involving a spinodal decomposition (SD) type phase separation due to the orientation …

The NuRD component Mbd3 is required for pluripotency of embryonic stem cells

K Kaji, IM Caballero, R MacLeod, J Nichols… - Nature cell …, 2006 - nature.com
Cells of early mammalian embryos have the potential to develop into any adult cell type, and
are thus said to be pluripotent. Pluripotency is lost during embryogenesis as cells commit to …

Tumor necrosis factor-α induces differentiation of and bone resorption by osteoclasts

Y Azuma, K Kaji, R Katogi, S Takeshita… - Journal of Biological …, 2000 - ASBMB
Osteoclast progenitors differentiate into mature osteoclasts in the presence of receptor
activator of NF-κB (RANK) ligand on stromal or osteoblastic cells and monocyte macrophage …

Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells

K Kaji, J Nichols, B Hendrich - 2007 - journals.biologists.com
Mbd3 is a core component of the NuRD (Nucleosome Remodeling and Histone
Deacetylation) co-repressor complex, and NuRD-mediated silencing has been implicated in …