Background New drugs and new evidence concerning the use of established treatments
have become available since the publication of the first European League Against …

The benefits of drug therapy for asthma have been well established, but adherence to
treatment is poor, and this might be associated with an increased risk of asthma …

A collaboration of multidisciplinary experts on the delivery of pharmaceutical aerosols was
facilitated by the European Respiratory Society (ERS) and the International Society for …

Background Gout is one of the most frequently occurring rheumatic diseases, worldwide.
Given the well‐known drawbacks of the regular treatments for acute gout (non‐steroidal anti …

Objective Existing criteria for the classification of gout have suboptimal sensitivity and/or
specificity, and were developed at a time when advanced imaging was not available. The …

We recently established conditions allowing for long-term expansion of epithelial organoids
from intestine, recapitulating essential features of the in vivo tissue architecture. Here we …

Background Non-steroidal anti-inflammatory drugs and colchicine used to treat gout arthritis
have gastrointestinal, renal, and cardiovascular adverse effects. Systemic corticosteroids …

Identifying subjects with cystic fibrosis (CF) who may benefit from cystic fibrosis
transmembrane conductance regulator (CFTR)–modulating drugs is time-consuming, costly …

Morphogen gradients contribute to pattern formation by determining positional information in
morphogenetic fields,. Interpretation of positional information is thought to rely on direct …

Background Most cases of acute gouty arthritis are diagnosed in primary care and without
joint fluid analysis in many instances. Our objectives were to estimate the validity of this …