Comparative analysis of multiple genomes in a phylogenetic framework dramatically
improves the precision and sensitivity of evolutionary inference, producing more robust …

Materials and Methods.-Samples of mitomycin C were kindly provided by Dr. J. Lein, Bristol
Laboratories, Syracuse, NY, by Dr. RB Ross, Cancer Chemotherapy National Service …

OBJECTIVE To clarify the clinical presentation and course of patients with spontaneous
pneumomediastinum (SP) and to determine the usefulness of diagnostic testing in these …

Mitomycins and porfiromycin, generally nonreactive in the natural oxidized state, behave as
bifunctional" alkylating" agents upon chemical or enzymatic reduction, followed by …

Cough persisting beyond 8 weeks (ie, chronic cough) is one of the most common reasons
for an outpatient visit. A protracted cough can negatively affect one's quality of life by causing …

Identifying the genomic regions bound by sequence-specific regulatory factors is central
both to deciphering the complex DNA cis-regulatory code that controls transcription in …

OBJECTIVE Patients with hereditary hemorrhagic telangiectasia (HHT) are known to suffer
from high rates of cerebral arteriovenous malformations (AVMs). The authors performed a …

Description: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant
disease with an estimated prevalence of 1 in 5000 that is characterized by the presence of …

The phylogenetic relationship of the now fully sequenced species Drosophila erecta and D.
yakuba with respect to the D. melanogaster species complex has been a subject of …

The gene expression pattern specified by an animal regulatory sequence is generally
viewed as arising from the particular arrangement of transcription factor binding sites it …