User profiles for "author:Gluud C"

Christian Gluud

The Copenhagen Trial Unit, Centre for Clinical Intervention Research
Verified email at ctu.dk
Cited by 69966

Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis

G Bjelakovic, D Nikolova, LL Gluud, RG Simonetti… - Jama, 2007 - jamanetwork.com
Context Antioxidant supplements are used for prevention of several diseases. Objective To
assess the effect of antioxidant supplements on mortality in randomized primary and …

Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases

G Bjelakovic, D Nikolova, LL Gluud… - Cochrane database …, 2012 - cochranelibrary.com
Antioxidant supplements for prevention of mortality in healthy participants and patients with
various diseases - Bjelakovic, G - 2012 | Cochrane Library Skip to Content Cookies Our site …

Vitamin D supplementation for prevention of mortality in adults

G Bjelakovic, LL Gluud, D Nikolova… - Cochrane database …, 2014 - cochranelibrary.com
Background Available evidence on the effects of vitamin D on mortality has been
inconclusive. In a recent systematic review, we found evidence that vitamin D 3 may …

Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study

L Wood, M Egger, LL Gluud, KF Schulz, P Jüni… - bmj, 2008 - bmj.com
Objective To examine whether the association of inadequate or unclear allocation
concealment and lack of blinding with biased estimates of intervention effects varies with the …

When and how should multiple imputation be used for handling missing data in randomised clinical trials–a practical guide with flowcharts

JC Jakobsen, C Gluud, J Wetterslev… - BMC medical research …, 2017 - Springer
Background Missing data may seriously compromise inferences from randomised clinical
trials, especially if missing data are not handled appropriately. The potential bias due to …

Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses

LL Kjaergard, J Villumsen, C Gluud - Annals of internal medicine, 2001 - acpjournals.org
Purpose: To explore whether reported methodologic quality affects estimated intervention
effects in randomized trials and contributes to discrepancies between the results of large …

Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis

J Wetterslev, K Thorlund, J Brok, C Gluud - Journal of clinical epidemiology, 2008 - Elsevier
BACKGROUND AND OBJECTIVE: Cumulative meta-analyses are prone to produce
spurious P< 0.05 because of repeated testing of significance as trial data accumulate …

Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials

J Savović, HE Jones, DG Altman, RJ Harris… - Annals of internal …, 2012 - acpjournals.org
Published evidence suggests that aspects of trial design lead to biased intervention effect
estimates, but findings from different studies are inconsistent. This study combined data from …

Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis

KS Gurusamy, C Davidson, C Gluud… - Cochrane Database …, 2013 - cochranelibrary.com
Background Gallstones are present in about 10% to 15% of the adult western population.
Between 1% and 4% of these adults become symptomatic in a year (the majority due to …

Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological …

J Savović, HE Jones, DG Altman, RJ Harris… - Health technology …, 2012 - boris.unibe.ch
The design of randomised controlled trials (RCTs) should incorporate characteristics (such
as concealment of randomised allocation and blinding of participants and personnel) that …