The glutamatergic neuromuscular synapse in Drosophila forms and differentiates into
distinct boutons in the embryo and grows by sprouting new boutons throughout larval life …

Postsynaptic sensitivity to glutamate was genetically manipulated at the Drosophila
neuromuscular junction (NMJ) to test whether postsynaptic activity can regulate presynaptic …

The robo gene in Drosophila was identified in a large-scale mutant screen for genes that
control the decision by axons to cross the CNS midline. In robo mutants, too many axons …

Understanding molecular-scale architecture of cells requires determination of 3D locations
of specific proteins with accuracy matching their nanometer-length scale. Existing electron …

Increased neuronal activity (eag Shaker mutants) and cAMP concentration (dunce mutants)
lead to increased synaptic structure and function at the Drosophila neuromuscular junction …

Drosophila melanogaster has a rich repertoire of innate and learned behaviors. Its 100,000-
neuron brain is a large but tractable target for comprehensive neural circuit mapping. Only …

The identification of synaptic partners is challenging in dense nerve bundles, where many
processes occupy regions beneath the resolution of conventional light microscopy. To …

Animal behaviour arises from computations in neuronal circuits, but our understanding of
these computations has been frustrated by the lack of detailed synaptic connection maps, or …

We conducted a large-scale screen for Drosophila mutants that have structural
abnormalities of the larval neuromuscular junction (NMJ). We recovered mutations in wishful …

Synaptic connections in the nervous system are directed onto specific cellular and
subcellular targets. Synaptic guidepost cells in the C. elegans vulval epithelium drive …