User profiles for "author:Berman BP"

Benjamin P Berman

Associate Professor, The Hebrew University of Jerusalem School of Medicine
Verified email at mail.huji.ac.il
Cited by 51958

The Genome Sequence of Drosophila melanogaster

MD Adams, SE Celniker, RA Holt, CA Evans… - Science, 2000 - science.org
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

Annotation of the Drosophila melanogastereuchromatic genome: a systematic review

S Misra, MA Crosby, CJ Mungall, BB Matthews… - Genome biology, 2002 - Springer
Background The recent completion of the Drosophila melanogaster genomic sequence to
high quality and the availability of a greatly expanded set of Drosophila cDNA sequences …

The psychencode project

S Akbarian, C Liu, JA Knowles, FM Vaccarino… - Nature …, 2015 - nature.com
Recent research on disparate psychiatric disorders has implicated rare variants in genes
involved in global gene regulation and chromatin modification, as well as many common …

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains

BP Berman, DJ Weisenberger, JF Aman, T Hinoue… - Nature …, 2012 - nature.com
Extensive changes in DNA methylation are common in cancer and may contribute to
oncogenesis through transcriptional silencing of tumor-suppressor genes. Genome-scale …

Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome

BP Berman, Y Nibu, BD Pfeiffer… - Proceedings of the …, 2002 - National Acad Sciences
A major challenge in interpreting genome sequences is understanding how the genome
encodes the information that specifies when and where a gene will be expressed. The first …

[PDF][PDF] Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

H Noushmehr, DJ Weisenberger, K Diefes, HS Phillips… - Cancer cell, 2010 - cell.com
We have profiled promoter DNA methylation alterations in 272 glioblastoma tumors in the
context of The Cancer Genome Atlas (TCGA). We found that a distinct subset of samples …

The chromatin accessibility landscape of primary human cancers

MR Corces, JM Granja, S Shams, BH Louie… - Science, 2018 - science.org
INTRODUCTION Cancer is one of the leading causes of death worldwide. Although the 2%
of the human genome that encodes proteins has been extensively studied, much remains to …

Global analysis of patterns of gene expression during Drosophilaembryogenesis

P Tomancak, BP Berman, A Beaton, R Weiszmann… - Genome biology, 2007 - Springer
Background Cell and tissue specific gene expression is a defining feature of embryonic
development in multi-cellular organisms. However, the range of gene expression patterns …

Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules

TK Kelly, Y Liu, FD Lay, G Liang, BP Berman… - Genome …, 2012 - genome.cshlp.org
DNA methylation and nucleosome positioning work together to generate chromatin
structures that regulate gene expression. Nucleosomes are typically mapped using …

Scientific workflow applications on Amazon EC2

G Juve, E Deelman, K Vahi, G Mehta… - 2009 5th IEEE …, 2009 - ieeexplore.ieee.org
The proliferation of commercial cloud computing providers has generated significant interest
in the scientific computing community. Much recent research has attempted to determine the …