The excitement and controversy surrounding the potential role of human embryonic stem
(ES), cells in transplantation therapy have often overshadowed their potentially more …

Satellite cells purified from adult skeletal muscle can participate extensively in muscle
regeneration and can also re-populate the satellite cell pool, suggesting that they have …

PAX7 is a paired-homeobox transcription factor that specifies the myogenic identity of
muscle stem cells and acts as a nodal factor by stimulating proliferation while inhibiting …

Background: The initial stages of phagocytosis and cell motility resemble each other. The
extension of a pseudopod at the leading edge of a migratory cell and the formation of a …

Per-and polyfluoroalkyl substances (PFAS) are a wide range of chemicals that are used in a
variety of consumer and industrial products leading to direct human exposure. Many PFAS …

Protein lysine acetylation is a post-translational modification that regulates protein structure
and function. It is targeted to proteins by lysine acetyltransferases (KATs) or removed by …

The growing number of chemicals in the current consumer and industrial markets presents a
major challenge for regulatory programs faced with the need to assess the potential risks …

The mineralocorticoid receptor (MR) is a tightly regulated nuclear hormone receptor that
selectively transmits corticosteroid signals. Steroid treatment transforms MR from a …

Epigenetic mechanisms are of fundamental importance for resolving and maintaining
cellular identity. The mechanisms regulating muscle stem and progenitor cell identity have …

Muscle function and health progressively deteriorate during the progression of muscle
dystrophies. The ability to objectively characterize muscle function and muscle damage is …