γ-Aminobutyric acid in brain: its formation from glutamic acid.

E Roberts, S Frankel - Journal of Biological Chemistry, 1950 - cabdirect.org
Free γ-aminobutyric acid was found in brain. extracts. Experiments with C 14-labelled
glutamic acid showed that this substance served as a pre cursor for y-aminobutyric acid. It is …

A half century of γ-aminobutyric acid

TG Smart, FA Stephenson - Brain and Neuroscience …, 2019 - journals.sagepub.com
γ-aminobutyric acid and its two major receptor subtypes: the γ-aminobutyric acid A and γ-aminobutyric
acid … molecule’ acting at a single γ-aminobutyric acid receptor type, to one of the …

[PDF][PDF] The role and the mechanism of γ-aminobutyric acid during central nervous system development

K Li, E Xu - Neuroscience bulletin, 2008 - researchgate.net
… Abstract: γ-aminobutyric acid (GABA) is an inhibitory neurotransmitter in adult
mammalian central nervous system (CNS). … Amino acid, including glutamate, aspartic acid …

Regulation of γaminobutyric acid synthesis in the brain

DL Martin, K Rimvall - Journal of neurochemistry, 1993 - Wiley Online Library
γAminobutyric acid (GABA) is synthesized in brain in at least two compartments, commonly
called the transmitter and metabolic compartments, and because reglatory processes must …

Factor I and γ-aminobutyric acid

A Bazemore, KAC Elliott, E Florey - Nature, 1956 - nature.com
EXTRACTS of brain and spinal cord of mammals inhibit impulse generation in stretch receptor
neurons of the crayfish 1 . The substance or substances responsible for this action has …

γ-Aminobutyric acid in peripheral tissues

C Tanaka - Life sciences, 1985 - Elsevier
Significant amounts of γ-aminobutyric acid (GABA), an endogenous amino acid, are present
in mammalian peripheral tissues. This finding led to the suggestion that GABA may act as a …

Metabolic and neurophysiological roles of γ-aminobutyric acid

E Roberts, E Eidelberg - International Review of Neurobiology, 1960 - Elsevier
Publisher Summary This chapter discusses γ-aminobutyric acid (GABA), a substance that
has a unique occurrence in the central nervous system (CNS). The chapter focuses on those …

The action of γ-aminobutyric acid on cortical neurones

K Krnjević, S Schwartz - Experimental brain research, 1967 - Springer
In cats under pentobarbitone anaesthesia, GABA was tested on cortical, pericruciate neurones
and its action compared with IPSPs evoked by surface stimulation. GABA was applied to …

The Nature of γ-Aminobutyric Acid

CF Baxter - Metabolic Reactions in the Nervous System, 1970 - Springer
The first reference to γ-aminobutyric acid (GABA) appeared in 1883 when the synthesis of a
compound named “Piperidinsaure” was reported. (1) Subsequently, the metabolism of …

Recent advances in γ‐aminobutyric acid (GABA) properties in pulses: an overview

N Nikmaram, BN Dar, S Roohinejad… - Journal of the …, 2017 - Wiley Online Library
… Among these bioactive compounds, γ-aminobutyric acid (GABA), a non-proteinogenic
amino acid with numerous reported health benefits (eg anti-diabetic and hypotensive effects, …