New perspectives in food allergy

M De Martinis, MM Sirufo, M Suppa… - International journal of …, 2020 - mdpi.com
The improvement of the knowledge of the pathophysiological mechanisms underlying the
tolerance and sensitization to food antigens has recently led to a radical change in the …

Food allergy and hypersensitivity reactions in children and adults—A review

SG Tedner, A Asarnoj, H Thulin… - Journal of internal …, 2022 - Wiley Online Library
Adverse reactions after food intake are commonly reported and a cause of concern and
anxiety that can lead to a very strict diet. The severity of the reaction can vary depending on …

Mechanisms governing anaphylaxis: inflammatory cells, mediators, endothelial gap junctions and beyond

SMT Nguyen, CP Rupprecht, A Haque… - International journal of …, 2021 - mdpi.com
Anaphylaxis is a severe, acute, life-threatening multisystem allergic reaction resulting from
the release of a plethora of mediators from mast cells culminating in serious respiratory …

Mast cell-mediated immune regulation in health and disease

KN Dileepan, VV Raveendran, R Sharma… - Frontiers in …, 2023 - frontiersin.org
Mast cells are important components of the immune system, and they perform pro-
inflammatory as well as anti-inflammatory roles in the complex process of immune regulation …

[HTML][HTML] Update of the S2k guideline on the management of IgE-mediated food allergies

M Worm, I Reese, B Ballmer-Weber, K Beyer… - Allergologie …, 2021 - ncbi.nlm.nih.gov
Immunoglobulin E (IgE)-mediated food allergies are divided into primary and secondary
food allergies, which can vary in severity.–Primary food allergies arise primarily (most likely) …

[HTML][HTML] Serological profiling reveals hsa-miR-451a as a possible biomarker of anaphylaxis

W Francuzik, K Pažur, M Dalke, S Dölle-Bierke… - JCI insight, 2022 - ncbi.nlm.nih.gov
Background There is a need to support the diagnosis of anaphylaxis by objective markers.
miRNAs are promising noncoding RNA species that may serve as serological biomarkers …

Anaphylaxis knowledge gaps and future research priorities: a consensus report

TE Dribin, D Schnadower, J Wang… - Journal of Allergy and …, 2022 - Elsevier
Background Despite a better understanding of the epidemiology, pathogenesis, and
management of patients with anaphylaxis, there remain knowledge gaps. Enumerating and …

CpG adjuvant in allergen-specific immunotherapy: finding the sweet spot for the induction of immune tolerance

G Montamat, C Leonard, A Poli, L Klimek… - Frontiers in …, 2021 - frontiersin.org
Prevalence and incidence of IgE-mediated allergic diseases have increased over the past
years in developed and developing countries. Allergen-specific immunotherapy (AIT) is …

Advances, practical implementation, and unmet needs regarding oral immunotherapy for food allergy

KP Perrett, SB Sindher, P Begin, J Shanks… - The Journal of Allergy …, 2022 - Elsevier
Treatment of food allergy is a rapidly changing landscape, with arguably, the most significant
advancement in recent years, the transition of oral immunotherapy (OIT) to clinical practice …

[HTML][HTML] Differences in gut microbiota between allergic rhinitis, atopic dermatitis, and skin urticaria: a pilot study

YJ Su, SD Luo, CY Hsu, HC Kuo - Medicine, 2021 - journals.lww.com
Methods. We enrolled 19 eczemas, nine hives, and 11 allergic rhinitis patients in this study.
Fecal samples were examined using 16S ribosomal ribonucleic acid amplicon sequencing …