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Lynette Tan, Kok Wee Chong, Si Hui Goh

2020/9

Singapore Medical Journal

61

9

497

Wolters Kluwer--Medknow Publications

Dear Sir, We herein report a case of a young girl who developed an adverse drug reaction (ADR) to a commonly prescribed lysozyme Page 1 497 Letter to the Editor Dear Sir, We herein report a case of a young girl who developed an adverse drug reaction (ADR) to a commonly prescribed lysozyme-containing mucolytic. Our patient had a background of infantile atopic dermatitis, (cow’s) milk anaphylaxis and egg allergy. At three years of age, she visited her family doctor for an upper respiratory tract infection and was prescribed Leftose®, a lysozyme-containing product, for the first time. Within 30 minutes of Leftose ingestion, she developed generalised urticaria. There were no systemic complaints. She was given oral antihistamines and monitored in the hospital for one day. A subsequent prick-to-prick test to the Leftose syrup confirmed immediate hypersensitivity with wheal size of 14 mm. A skin prick test to egg white …