In this HCUP Statistical Brief, we use historical HCUP inpatient data from 2003 through 2011 along with early 2012 data from nine HCUP States to develop national projections of 2012 and 2013 hospital costs and other inpatient statistics for all hospitalizations (any reason). We examine five distinct hospital service lines that together encompass all types of inpatient discharges: medical, surgical, injury, mental health, and maternal and neonatal. Differences greater than 10 percent between annual weighted estimates are noted in the text. Because analyses in this Statistical Brief are based on all discharges from all States weighted to a national level, the values may differ slightly from results reported from the HCUP Nationwide Inpatient Sample (NIS).