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Huntington's disease: silencing a brutal killer

Exp Neurol. 2009 Dec;220(2):226-9. doi: 10.1016/j.expneurol.2009.09.017. Epub 2009 Sep 25.
No abstract available

Publication types

  • Review

MeSH terms

  • Alleles
  • Animals
  • Base Pair Mismatch
  • Exons / genetics
  • Gene Deletion
  • Gene Silencing*
  • Humans
  • Huntingtin Protein
  • Huntington Disease / genetics*
  • Huntington Disease / therapy*
  • Nerve Tissue Proteins / genetics
  • Nuclear Proteins / genetics
  • Polymorphism, Single Nucleotide / genetics
  • RNA, Small Interfering / adverse effects
  • RNA, Small Interfering / therapeutic use
  • Rats

Substances

  • Htt protein, rat
  • Huntingtin Protein
  • Nerve Tissue Proteins
  • Nuclear Proteins
  • RNA, Small Interfering