DNA and RNA synthesis: antifolates

Chem Rev. 2005 Feb;105(2):593-620. doi: 10.1021/cr0301144.

Authors

Ivan M Kompis¹, Khalid Islam, Rudolf L Then

Affiliation

¹ ARPIDA Ltd, Dammstrasse 36, 4142 Münchenstein, Switzerland.

PMID: 15700958
DOI: 10.1021/cr0301144

No abstract available

Publication types

Review

MeSH terms

Animals
Anti-Infective Agents / chemistry
Anti-Infective Agents / pharmacology*
Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology*
DNA / biosynthesis*
Drug Resistance, Microbial
Drug Resistance, Neoplasm
Folic Acid Antagonists / chemistry
Folic Acid Antagonists / pharmacology*
Humans
Molecular Structure
RNA / biosynthesis*
Tetrahydrofolate Dehydrogenase / metabolism*

Substances

Anti-Infective Agents
Antineoplastic Agents
Folic Acid Antagonists
RNA
DNA
Tetrahydrofolate Dehydrogenase