R01 MH115786/MH/NIMH NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2018	1
2019	4
2020	5
2024	0

1

Combination of HIV-1 and Diabetes Enhances Blood Brain Barrier Injury via Effects on Brain Endothelium and Pericytes.

Rom S, Gajghate S, Winfield M, Reichenbach NL, Persidsky Y. Rom S, et al. Int J Mol Sci. 2020 Jun 30;21(13):4663. doi: 10.3390/ijms21134663. Int J Mol Sci. 2020. PMID: 32630025 Free PMC article.

2

Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles.

Rom S, Heldt NA, Gajghate S, Seliga A, Reichenbach NL, Persidsky Y. Rom S, et al. Sci Rep. 2020 Apr 29;10(1):7274. doi: 10.1038/s41598-020-64349-x. Sci Rep. 2020. PMID: 32350344 Free PMC article.

3

let-7g counteracts endothelial dysfunction and ameliorating neurological functions in mouse ischemia/reperfusion stroke model.

Bernstein DL, Gajghate S, Reichenbach NL, Winfield M, Persidsky Y, Heldt NA, Rom S. Bernstein DL, et al. Brain Behav Immun. 2020 Jul;87:543-555. doi: 10.1016/j.bbi.2020.01.026. Epub 2020 Feb 1. Brain Behav Immun. 2020. PMID: 32017988 Free PMC article.

4

Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier.

Marcos-Contreras OA, Greineder CF, Kiseleva RY, Parhiz H, Walsh LR, Zuluaga-Ramirez V, Myerson JW, Hood ED, Villa CH, Tombacz I, Pardi N, Seliga A, Mui BL, Tam YK, Glassman PM, Shuvaev VV, Nong J, Brenner JS, Khoshnejad M, Madden T, Weissmann D, Persidsky Y, Muzykantov VR. Marcos-Contreras OA, et al. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3405-3414. doi: 10.1073/pnas.1912012117. Epub 2020 Jan 31. Proc Natl Acad Sci U S A. 2020. PMID: 32005712 Free PMC article.

5

miR-98 reduces endothelial dysfunction by protecting blood-brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model.

Bernstein DL, Zuluaga-Ramirez V, Gajghate S, Reichenbach NL, Polyak B, Persidsky Y, Rom S. Bernstein DL, et al. J Cereb Blood Flow Metab. 2020 Oct;40(10):1953-1965. doi: 10.1177/0271678X19882264. Epub 2019 Oct 10. J Cereb Blood Flow Metab. 2020. PMID: 31601141 Free PMC article.

6

Chronic Intrahippocampal Infusion of HIV-1 Neurotoxic Proteins: A Novel Mouse Model of HIV-1 Associated Inflammation and Neural Stem Cell Dysfunction.

Hill JD, Zuluaga-Ramirez V, Gajghate S, Winfield M, Persidsky Y. Hill JD, et al. J Neuroimmune Pharmacol. 2019 Sep;14(3):375-382. doi: 10.1007/s11481-019-09846-1. Epub 2019 Mar 23. J Neuroimmune Pharmacol. 2019. PMID: 30905008 Free PMC article.

7

Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain.

Marcos-Contreras OA, Brenner JS, Kiseleva RY, Zuluaga-Ramirez V, Greineder CF, Villa CH, Hood ED, Myerson JW, Muro S, Persidsky Y, Muzykantov VR. Marcos-Contreras OA, et al. J Control Release. 2019 May 10;301:54-61. doi: 10.1016/j.jconrel.2019.03.008. Epub 2019 Mar 11. J Control Release. 2019. PMID: 30871995 Free PMC article.

8

Hyperglycemia-Driven Neuroinflammation Compromises BBB Leading to Memory Loss in Both Diabetes Mellitus (DM) Type 1 and Type 2 Mouse Models.

Rom S, Zuluaga-Ramirez V, Gajghate S, Seliga A, Winfield M, Heldt NA, Kolpakov MA, Bashkirova YV, Sabri AK, Persidsky Y. Rom S, et al. Mol Neurobiol. 2019 Mar;56(3):1883-1896. doi: 10.1007/s12035-018-1195-5. Epub 2018 Jul 5. Mol Neurobiol. 2019. PMID: 29974394 Free PMC article.

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