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Natural protein engineering in the Ω-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas-derived cephalosporinase.
Mack AR, Kumar V, Taracila MA, Mojica MF, O'Shea M, Schinabeck W, Silver G, Hujer AM, Papp-Wallace KM, Chen S, Haider S, Caselli E, Prati F, van den Akker F, Bonomo RA. Mack AR, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0079123. doi: 10.1128/aac.00791-23. Epub 2023 Oct 18. Antimicrob Agents Chemother. 2023. PMID: 37850746 Free PMC article.
Structure of the SHV-1 beta-lactamase.
Kuzin AP, Nukaga M, Nukaga Y, Hujer AM, Bonomo RA, Knox JR. Kuzin AP, et al. Among authors: bonomo ra. Biochemistry. 1999 May 4;38(18):5720-7. doi: 10.1021/bi990136d. Biochemistry. 1999. PMID: 10231522
High-level expression of chromosomally encoded SHV-1 beta-lactamase and an outer membrane protein change confer resistance to ceftazidime and piperacillin-tazobactam in a clinical isolate of Klebsiella pneumoniae.
Rice LB, Carias LL, Hujer AM, Bonafede M, Hutton R, Hoyen C, Bonomo RA. Rice LB, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2000 Feb;44(2):362-7. doi: 10.1128/AAC.44.2.362-367.2000. Antimicrob Agents Chemother. 2000. PMID: 10639363 Free PMC article.
735 results