Appleton BA - Search Results

1

Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site.

Bostrom J, Yu SF, Kan D, Appleton BA, Lee CV, Billeci K, Man W, Peale F, Ross S, Wiesmann C, Fuh G. Bostrom J, et al. Among authors: appleton ba. Science. 2009 Mar 20;323(5921):1610-4. doi: 10.1126/science.1165480. Science. 2009. PMID: 19299620

2

The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes.

Appleton BA, Wu P, Wiesmann C. Appleton BA, et al. Structure. 2006 Jan;14(1):87-96. doi: 10.1016/j.str.2005.09.013. Structure. 2006. PMID: 16407068 Free article.

3

Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain.

Zhang Y, Appleton BA, Wu P, Wiesmann C, Sidhu SS. Zhang Y, et al. Among authors: appleton ba. Protein Sci. 2007 Aug;16(8):1738-50. doi: 10.1110/ps.072833207. Protein Sci. 2007. PMID: 17656586 Free PMC article.

4

Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.

Appleton BA, Wu P, Maloney J, Yin J, Liang WC, Stawicki S, Mortara K, Bowman KK, Elliott JM, Desmarais W, Bazan JF, Bagri A, Tessier-Lavigne M, Koch AW, Wu Y, Watts RJ, Wiesmann C. Appleton BA, et al. EMBO J. 2007 Nov 28;26(23):4902-12. doi: 10.1038/sj.emboj.7601906. Epub 2007 Nov 8. EMBO J. 2007. PMID: 17989695 Free PMC article.

5

Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domains.

Barthelemy PA, Raab H, Appleton BA, Bond CJ, Wu P, Wiesmann C, Sidhu SS. Barthelemy PA, et al. Among authors: appleton ba. J Biol Chem. 2008 Feb 8;283(6):3639-3654. doi: 10.1074/jbc.M708536200. Epub 2007 Nov 28. J Biol Chem. 2008. PMID: 18045863 Free article.

6

Inhibition of Wnt signaling by Dishevelled PDZ peptides.

Zhang Y, Appleton BA, Wiesmann C, Lau T, Costa M, Hannoush RN, Sidhu SS. Zhang Y, et al. Among authors: appleton ba. Nat Chem Biol. 2009 Apr;5(4):217-9. doi: 10.1038/nchembio.152. Epub 2009 Mar 1. Nat Chem Biol. 2009. PMID: 19252499

7

Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors--insight into heterotrimeric IL-1 signaling complexes.

Lingel A, Weiss TM, Niebuhr M, Pan B, Appleton BA, Wiesmann C, Bazan JF, Fairbrother WJ. Lingel A, et al. Among authors: appleton ba. Structure. 2009 Oct 14;17(10):1398-410. doi: 10.1016/j.str.2009.08.009. Structure. 2009. PMID: 19836339 Free PMC article.

8

Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.

Appleton BA, Zhang Y, Wu P, Yin JP, Hunziker W, Skelton NJ, Sidhu SS, Wiesmann C. Appleton BA, et al. J Biol Chem. 2006 Aug 4;281(31):22312-22320. doi: 10.1074/jbc.M602901200. Epub 2006 May 31. J Biol Chem. 2006. PMID: 16737969 Free article.

9

Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3.

Runyon ST, Zhang Y, Appleton BA, Sazinsky SL, Wu P, Pan B, Wiesmann C, Skelton NJ, Sidhu SS. Runyon ST, et al. Among authors: appleton ba. Protein Sci. 2007 Nov;16(11):2454-71. doi: 10.1110/ps.073049407. Protein Sci. 2007. PMID: 17962403 Free PMC article.

10

A structural portrait of the PDZ domain family.

Ernst A, Appleton BA, Ivarsson Y, Zhang Y, Gfeller D, Wiesmann C, Sidhu SS. Ernst A, et al. Among authors: appleton ba. J Mol Biol. 2014 Oct 23;426(21):3509-19. doi: 10.1016/j.jmb.2014.08.012. Epub 2014 Aug 23. J Mol Biol. 2014. PMID: 25158098

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