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Central Pattern Generators
Central pattern generators (CPGs) are circuits of neurons – coupled by chemical synapses and often gap junctions (Marder et al., Dev Neurobiol... -
The use of digital tools in rare neurological diseases towards a new care model: a narrative review
Rare neurological diseases as a whole share peculiar features as motor and/or cognitive impairment, an elevated disability burden, a frequently...
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Arthrogene Muskelinhibition
Arthrogene Muskelinhibition ist eine spezifische Form der unzureichenden motorischen Steuerung, die durch Erkrankung, Über- oder Fehlbelastung eines... -
Exercise and fatigue: integrating the role of K+, Na+ and Cl− in the regulation of sarcolemmal excitability of skeletal muscle
Perturbations in K + have long been considered a key factor in skeletal muscle fatigue. However, the exercise-induced changes in K + ...
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Quergestreifte Muskulatur
Die quergestreifte Muskulatur beinhaltet die Skelett- und Herzmuskulatur. Der Skelettmuskulatur kommt primär eine übergeordnete Bedeutung bei allen... -
MiR206 and 423-3p Are Differently Modulated in Fast and Slow-Progressing Amyotrophic Lateral Sclerosis Patients
Amyotrophic lateral sclerosis (ALS) is a rare neuromuscular disease with a wide disease progression. Despite several efforts to develop efficient...
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Surgery in the Peripheral Nervous System
Peripheral nerve monitoring provides diagnostic information that can guide surgical decision-making. An extension of the physical examination,... -
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Skeletal muscle of young females under resistance exercise exhibits a unique innate immune cell infiltration profile compared to males and elderly individuals
Muscle damage resulting from physical activities such as exercise triggers an immune response crucial for tissue repair and recovery. This study...
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Essential elements of radical pair magnetosensitivity in Drosophila
Many animals use Earth’s magnetic field (also known as the geomagnetic field) for navigation
1 . The favoured mechanism for magnetosensitivity involves... -
Role of the immune system in amyotrophic lateral sclerosis. Analysis of the natural killer cells and other circulating lymphocytes in a cohort of ALS patients
AimsNeuroinflammation might be involved in the degeneration and progression of Amyotrophic Lateral Sclerosis (ALS). Here, we studied the role of the...
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Schlafattacken, Hirnstammsyndrom und Gangstörung
Die IgLON5- Enzephalitis ist eine Tauopathie mit gleichzeitigem Nachweis von IgLON5-Antikörpern im Blut und zumeist im Liquor. In der Mehrzahl der... -
Sensorimotor recalibration of postural control strategies occurs after whole body vibration
Efficient postural control results from an effective interplay between sensory feedbacks integration and muscle modulation and can be affected by...
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A neuromuscular model of human locomotion combines spinal reflex circuits with voluntary movements
Existing models of human walking use low-level reflexes or neural oscillators to generate movement. While appropriate to generate the stable,...
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Initial action output and feedback-guided motor behaviors in autism spectrum disorder
BackgroundSensorimotor issues are common in autism spectrum disorder (ASD), related to core symptoms, and predictive of worse functional outcomes....
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Gap Junctions and Very Fast Oscillations
In this chapter we shall discuss the evidence for the existence of an interesting sort of electrical synapse: gap junctions between the axons of... -
The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder in which the neuromuscular junction progressively degenerates,...
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Development of a Robotic Rat Hindlimb Model
This paper discusses the design decisions, process, and results for a set of robotic rat hindlimbs scaled up to 2.5 times the size of the rat. The...