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Transcriptional Control of Lipid Metabolism
Transcriptional control of lipid metabolism uses a framework that parallels the control of lipid metabolism at the protein or enzyme level, via... -
Basal Transcriptional Machinery
In this chapter, we will discuss the impact of TSS regions, which are also known as core promoters. This is a prerequisite for understanding how... -
Post-Transcriptional Gene Regulation
This volume presents the most recent advances in techniques for studying the post-transcriptional regulation of gene expression (PTR). With sections... -
Disentangling genetic effects on transcriptional and post-transcriptional gene regulation through integrating exon and intron expression QTLs
Expression quantitative trait loci (eQTL) studies typically consider exon expression of genes and discard intronic RNA sequencing reads despite their...
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Emerging insights into transcriptional condensates
Eukaryotic transcription, a fundamental process that governs cell-specific gene expression, has long been the subject of extensive investigations in...
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Transcriptional and Post-transcriptional Regulation of Tuberization in Potato (Solanum tuberosum L.)
The transition from juvenile to adult stage is an important switch in the plant’s life cycle. Potato is a temperate staple food crop consumed...
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A Gene-Community Overview of Transcriptional Dynamics During Neurodevelopment
The brain is a complex network of anatomic functional modules called brain circuits. A brain circuit comprises structures that share transcriptional... -
Bioinformatic Analysis Reveals the Association of Human N-Terminal Acetyltransferase Complexes with Distinct Transcriptional and Post-Transcriptional Processes
N-terminal acetyltransferases (NAT) are the protein complexes that deposit the abundant N-terminal acetylation (Nt-Ac) on eukaryotic proteins, with...
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STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity
Transcription is a dynamic process. To detect the dynamic relationship among protein clusters of RNA polymerase II and coactivators, gene loci, and...
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Transcriptional and post-transcriptional control of autophagy and adipogenesis by YBX1
Obesity is strongly associated with metabolic diseases, which have become a global health problem. Exploring the underlying mechanism of adipogenesis...
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A robust ultrasensitive transcriptional switch in noisy cellular environments
Ultrasensitive transcriptional switches enable sharp transitions between transcriptional on and off states and are essential for cells to respond to...
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Post-transcriptional checkpoints in autoimmunity
Post-transcriptional regulation is a fundamental process in gene expression that has a role in diverse cellular processes, including immune...
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Transcriptional condensates: a blessing or a curse for gene regulation?
Whether phase-separation is involved in the organization of the transcriptional machinery and if it aids or inhibits the transcriptional process is a...
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Co-transcriptional gene regulation in eukaryotes and prokaryotes
Many steps of RNA processing occur during transcription by RNA polymerases. Co-transcriptional activities are deemed commonplace in prokaryotes, in...
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Transcriptional regulation of tomato fruit ripening
An intrinsic and genetically determined ripening program of tomato fruits often depends upon the appropriate activation of tissue- and stage-specific...
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Transcriptional Regulation of Gene Expression in Plant Abiotic Stress Response
This chapter offers an in-depth analysis of gene expression regulation through transcriptional mechanisms, with a particular focus on the significant... -
CRISPR-Based Transcriptional Activation in Drosophila
Overexpression is one of the classical approaches to study pleiotropic functions of genes of interest. To achieve overexpression, we often increase... -
Astrocytic transcriptional and epigenetic mechanisms of drug addiction
Addiction is a leading cause of disease burden worldwide and remains a challenge in current neuroscience research. Drug-induced lasting changes in...
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Transcriptional Regulation of Capsaicin Biosynthesis
The total amount of RNA transcribed in a tissue at specific point of time under constant environmental condition is referred to as transcriptome.... -
Community Structure in Transcriptional Regulatory Networks of Yeast Species
The genomic expression of living organisms is controlled by complex transcriptional regulation. Transcriptional regulatory networks, composed by...