Search

Search Results

1. Spermatogenesis and Semen

   The spermatozoa are the male gamete produced in the seminiferous tubule through spermatogenesis. The spermatozoa are derived from germinal...

   Pradip Kumar Das, Joydip Mukherjee, Dipak Banerjee in Textbook of Veterinary Physiology

   Chapter 2023
   

2. Disorders of Spermatogenesis and Spermiogenesis

   Male infertility is often caused by congenital or acquired disorders of spermatogenesis and spermiogenesis; with impaired semen quality ranging from...

   Hans-Christian Schuppe, Margot J. Wyrwoll, ... Frank Tüttelmann in Andrology

   Chapter 2023
   

3. Rattus norvegicus Spermatogenesis Colony-Forming Assays

   Knowledge gaps persist on signaling pathways and metabolic states in germ cells sufficient to support spermatogenesis independent of a somatic...

   Karen M. Chapman, Ashutosh Pudasaini, ... F. Kent Hamra in Germline Stem Cells

   Protocol 2023
   

4. SRSF2 is required for mRNA splicing during spermatogenesis

   Background

   RNA splicing plays significant roles in fundamental biological activities. However, our knowledge about the roles of alternative splicing...

   Wen-Long Lei, Zongchang Du, ... Qing-Yuan Sun in BMC Biology

   Article Open access 23 October 2023
   

5. Circular RNA regulates male spermatogenesis: a narrative review

   Spermatogenesis was crucial for adult male animals to achieve reproductive function, and this complex physiological process required timely and...

   Li-fan Peng, Hang Yu in Middle East Fertility Society Journal

   Article Open access 29 May 2024

6. Identification of hub genes associated with spermatogenesis by bioinformatics analysis

   Spermatogenesis is a complex process related to male infertility. Till now, the critical genes and specific mechanisms have not been elucidated...

   Shuang Liu, Yan-chao Bian, ... Chuan-ling Zhang in Scientific Reports

   Article Open access 27 October 2023
   

7. X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome

   Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature...

   Sofia B. Winge, Niels E. Skakkebaek, ... Kristian Almstrup in Cell Death & Disease

   Article Open access 05 June 2024
   

8. ClpP/ClpX deficiency impairs mitochondrial functions and mTORC1 signaling during spermatogenesis

   Caseinolytic protease proteolytic subunit (ClpP) and caseinolytic protease X (ClpX) are mitochondrial matrix peptidases that activate mitochondrial...

   Chenxi Guo, Yuan Xiao, ... Tianren Wang in Communications Biology

   Article Open access 05 October 2023
   

9. Retinoic acid mitigates the NSC319726-induced spermatogenesis dysfunction through cuproptosis-independent mechanisms

   Copper ionophore NSC319726 has attracted researchers' attention in treating diseases, particularly cancers. However, its potential effects on male...

   Haisheng Yi, Tong Chen, ... Hongliang Wang in Cell Biology and Toxicology

   Article Open access 01 May 2024
   

10. LncRNA5251 inhibits spermatogenesis via modification of cell-cell junctions

    Background

    Male factors-caused decline in total fertility has raised significant concern worldwide. LncRNAs have been identified to play various roles...

    Cong Zhang, Dongxin Lu, ... Yanni Feng in Biology Direct

    Article Open access 15 June 2023
    

11. Generation of rat offspring using spermatids produced through in vitro spermatogenesis

    An in vitro spermatogenesis method using mouse testicular tissue to produce fertile sperm was established more than a decade ago. Although this...

    Takafumi Matsumura, Kumiko Katagiri, ... Takehiko Ogawa in Scientific Reports

    Article Open access 26 July 2023
    

12. Single-cell RNA sequencing technology in human spermatogenesis: Progresses and perspectives

    Spermatogenesis, a key part of the spermiation process, is regulated by a combination of key cells, such as primordial germ cells, spermatogonial...

    Hanbo Jia, Wei Wang, ... Liqing Fan in Molecular and Cellular Biochemistry

    Article 02 September 2023
    

13. In Vitro Spermatogenesis

    In vitro spermatogenesis (IVS) englobes numerous culture techniques that range from single cell expansion and differentiation protocols to the 3D...

    Christine Wyns, Marc Kanbar in Female and Male Fertility Preservation

    Chapter 2022
    

14. Loss of PMFBP1 Disturbs Mouse Spermatogenesis by Downregulating HDAC3 Expression

    Purpose

    Polyamine modulating factor 1 binding protein (PMFBP1) acts as a scaffold protein for the maintenance of sperm structure. The aim of this...

    Weilong Xu, Zhoujuan Yao, ... Hui Zhang in Journal of Assisted Reproduction and Genetics

    Article 10 July 2023
    

15. The emerging and diverse roles of F-box proteins in spermatogenesis and male infertility

    F-box proteins play essential roles in various cellular processes of spermatogenesis by means of ubiquitylation and subsequent target protein...

    Xuan Zhuang, Jun Ruan, ... Zhiming Li in Cell Regeneration

    Article Open access 26 June 2024
    

16. The mitochondrial protease PARL is required for spermatogenesis

    Mitochondrial function plays an important role in the maintenance of male fertility. However, the mechanisms underlying mitochondrial defect-related...

    Sarah Schumacher, Laura Klose, ... Lars Fester in Communications Biology

    Article Open access 05 January 2024
    

17. Genetic and histopathological analysis of spermatogenesis after short-term testicular torsion in rats

    Background

    Patients with testicular torsion (TT) may exhibit impaired spermatogenesis from reperfusion injury after detorsion surgery. Alteration in...

    Hiroto Katami, Shingo Suzuki, ... Ryuichi Shimono in Pediatric Research

    Article 24 May 2023
    

18. Small RNAs, spermatogenesis, and male infertility: a decade of retrospect

    Small non-coding RNAs (sncRNAs), being the top regulators of gene expression, have been thoroughly studied in various biological systems, including...

    Meghali Joshi, Shruti Sethi, ... Singh Rajender in Reproductive Biology and Endocrinology

    Article Open access 04 November 2023
    

19. The molecular evolution of spermatogenesis across mammals

    The testis produces gametes through spermatogenesis and evolves rapidly at both the morphological and molecular level in mammals ^{1 – 6} , probably owing...

    Florent Murat, Noe Mbengue, ... Henrik Kaessmann in Nature

    Article Open access 21 December 2022
    

20. RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling

    Spermatogenesis is an extremely complex process, and any obstruction can cause male infertility. RhoGDIα has been identified as a risk of male...

    Haixia Zhu, Zongzhuang Wen, ... Jiangang Gao in Communications Biology

    Article Open access 23 February 2023