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Weighted Chaos Game Representation for Molecular Sequence Classification
Molecular sequence analysis is a crucial task in bioinformatics and has several applications in drug discovery and disease diagnosis. However,... -
Molecular classification of urothelial bladder carcinoma
Urothelial bladder carcinoma (UC) ranks among the top ten most commonly diagnosed cancers worldwide on an annual basis. The standardized...
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Molecular pathological classification of colorectal cancer—an update
Colorectal cancer (CRC) has a broad range of molecular alterations with two major mechanisms of genomic instability (chromosomal instability and...
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Research advances in the molecular classification of gastric cancer
Gastric cancer (GC) is a malignant tumor with one of the lowest five-year survival rates. Traditional first-line treatment regimens, such as platinum...
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A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker
Previous studies on the molecular classification of cholangiocarcinoma (CCA) focused on certain anatomical sites, and disregarded tissue...
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Molecular classification of hormone receptor-positive HER2-negative breast cancer
Hormone receptor-positive (HR + )/human epidermal growth factor receptor 2-negative (HER2 − ) breast cancer is the most prevalent type of breast cancer,...
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A multimodal graph neural network framework for cancer molecular subtype classification
BackgroundThe recent development of high-throughput sequencing has created a large collection of multi-omics data, which enables researchers to...
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It is time to implement molecular classification in endometrial cancer
A huge effort has been done in redefining endometrial cancer (EC) risk classes in the last decade. However, known prognostic factors (FIGO staging...
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Molecular Classification of Gastrointestinal and Pancreatic Neuroendocrine Neoplasms: Are We Ready for That?
In the last two decades, the increasing availability of technologies for molecular analyses has allowed an insight in the genomic alterations of...
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In silico screening of Fyn kinase inhibitors using classification-based QSAR model, molecular docking, molecular dynamics and ADME study
This study aimed to use a computational approach that combined the classification-based QSAR model, molecular docking, ADME studies, and molecular...
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Molecular classification and grading of meningioma
PurposeMeningiomas are the most common primary intracranial tumor in older adults (Ostrom et al. in Neuro Oncol 21(Suppl 5):v1–v100, 2019). Treatment...
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Identification of novel molecular subtypes to improve the classification framework of nasopharyngeal carcinoma
BackgroundNasopharyngeal carcinoma (NPC) treatment is largely based on a ‘one-drug-fits-all’ strategy in patients with similar pathological...
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Latent class analysis-derived classification improves the cancer-specific death stratification of molecular subtyping in colorectal cancer
The molecular subtypes of colorectal cancer (CRC) represent a comprehensive dissection of CRC heterogeneity. However, molecular feature-based...
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Molecular Determinants of Neurocognitive Deficits in Glioma: Based on 2021 WHO Classification
Cognitive impairment is a common feature among patients with diffuse glioma. The objective of the study is to investigate the relationship between...
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Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging
Molecular classification has transformed the management of brain tumors by enabling more accurate prognostication and personalized treatment....
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Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia
Genomic analyses have redefined the molecular subgrouping of pediatric acute lymphoblastic leukemia (ALL). Molecular subgroups guide...
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Molecular Property Diagnostic Suite Compound Library (MPDS-CL): a structure-based classification of the chemical space
Molecular Property Diagnostic Suite Compound Library (MPDS-CL) is an open-source Galaxy-based cheminformatics web portal which presents a...
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The Molecular Classification of Ovarian Cancer and Implication for Treatment
Ovarian cancers are divided into epithelial carcinomas, representing the majority of malignant ovarian tumours in adult women (90%) and... -
Classification of lung cancer with deep learning Res-U-Net and molecular imaging
Lung cancer is a prevalent malignancy, despite the great breakthroughs in detection and prevention, and it remains the important cause of death. In...
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Molecular-based classification of endometrial carcinoma in Northern Thailand: impact on prognosis and potential for implementation in resource-limited settings
BackgroundEndometrial carcinoma is molecularly categorized into four subgroups: polymerase-E exonuclease domain-mutant (POLE-mut), mismatch...