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Lipid Signalling Methods and Protocols
This volume covers the latest advancements in the study of lipid signaling. The chapters in this book cover topics such as neuronal cells such as...
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Lipid-Based Nanocarriers
Lipid-based nanocarriers (LNCs) are designed from lipid molecules to encapsulate hydrophobic compounds such as polyphenols, lipophilic vitamins,... -
Lipid Metabolism
Lipids are a heterogeneous group of water-insoluble compounds that are soluble in organic solvents. Besides being an important constituent of the... -
Transcriptional Control of Lipid Metabolism
Transcriptional control of lipid metabolism uses a framework that parallels the control of lipid metabolism at the protein or enzyme level, via... -
Lipid droplets and cellular lipid flux
Lipid droplets are dynamic organelles that store neutral lipids, serve the metabolic needs of cells, and sequester lipids to prevent lipotoxicity and...
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Endocrine Control of Lipid Metabolism
Lipids are essential in insects and play pleiotropic roles in energy storage, serving as a fuel for energy-driven processes such as reproduction,... -
Lipid Binding of SH2 Domains
The Src homology 2 (SH2) domain is a modular protein interaction domain that specifically recognizes the phosphotyrosine (pY) motif of a target... -
Genetics of Lipid Disorders
This chapter focuses on the genetics of common lipid disorders, collectively referred to as “dyslipidemia,” a component of the metabolic syndrome... -
An Overview of Lipid Metabolism
In this chapter, we provide a brief overview of lipid metabolism with a focused discussion and review of lipoproteins, endogenous and exogenous lipid... -
Kidney lipid dysmetabolism and lipid droplet accumulation in chronic kidney disease
Chronic kidney disease (CKD) is a global health problem with rising incidence and prevalence. Among several pathogenetic mechanisms responsible for...
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ER Membrane Lipid Composition and Metabolism: Lipidomic Analysis
Plant ER membranes are the major site of biosynthesis of several lipid families (phospholipids, sphingolipids, neutral lipids such as sterols and... -
Lipid-Based Nanocarriers for the Delivery of Phytoconstituents
Over the last decade, lipid-based nanocarriers have proven to be a good carrier for many pharmaceutical medications. Different types of lipid-based... -
A Lipid-Structured Model of Atherosclerotic Plaque Macrophages with Lipid-Dependent Kinetics
Atherosclerotic plaques are fatty growths in artery walls that cause heart attacks and strokes. Plaque formation is driven by macrophages that are...
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Liquid crystalline inverted lipid phases encapsulating siRNA enhance lipid nanoparticle mediated transfection
Efficient cytosolic delivery of RNA molecules remains a formidable barrier for RNA therapeutic strategies. Lipid nanoparticles (LNPs) serve as...
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PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in retinal pigment epithelium
Drusen, the yellow deposits under the retina, are composed of lipids and proteins, and represent a hallmark of age-related macular degeneration...
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Solid Lipid Nanoparticles for Drug Delivery
Solid lipid nanoparticlesSolid lipid nanoparticles (SLNs) are promising carriers that allow for the delivery of poorly water-soluble drugs and have... -
Lipid-Related Pathophysiology of ASD
Autism spectrum disorder (ASD) is the unitary diagnostic classification for a heterogeneous neurodevelopmental disorder characterized by deficits in... -
Lipid Biomass to Biofuel
Fossil fuels are the main energy sources worldwide even today. But with the alarming pace at which fossil fuels are exhausting, there would be a need... -
LiLA: lipid lung-based ATLAS built through a comprehensive workflow designed for an accurate lipid annotation
Accurate lipid annotation is crucial for understanding the role of lipids in health and disease and identifying therapeutic targets. However,...