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Potentiometric Sensors Sensitive to Some Cephalosporin Antibiotics: Properties and Applications
AbstractWe developed unmodified and modified solid-contact potentiometric sensors (tubular and screen-printed) for determining some cephalosporin...
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Industrial Enzymatic Production of Cephalosporin-Based β-Lactams
Cephalosporins are chemically closely related to penicillins both work by inhibiting the cell wall synthesis of bacteria. The first generation... -
RETRACTED ARTICLE: Molecular docking simulation, drug-likeness assessment, and pharmacokinetic study of some cephalosporin analogues against a penicillin-binding protein of Salmonella typhimurium
In pursuit of novel antibiotics that could curb the growing trend of multidrug resistance by Salmonella typhimurium , a data set of some cephalosporin...
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Efficacy of fosfomycin compared to second generation cephalosporin flumarin as antimicrobial prophylaxis for transrectal ultrasound-guided prostate biopsy: a single center retrospective study
BackgroundFluoroquinolone has been the historic choice of antimicrobial prophylaxis for transrectal ultrasound (TRUS) guided prostate biopsy....
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Oral Manifestations of Bacterial Infections
Bacterial infections that cause oral mucosal lesions include scarlet fever, diphtheria, and leprosy. The oral manifestations may be non-specific in... -
The Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy: Part III Non-penicillin and Non-cephalosporin Drugs
IntroductionUnderstanding the pharmacokinetics (PK) of antimicrobial drugs in pregnant women is crucial to provide effective and safe treatment. This...
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Oral colonization by gram-negative bacilli in patients with hematologic malignancies and solid tumors compared with healthy controls
BackgroundColonization of the oropharynx with gram-negative bacilli (GNB) is considered a negative prognostic factor in immunocompromised...
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Application of computer-based diagnostic light enhanced medical imaging in the analysis of infection factors in oral and maxillofacial surgery
The distribution of nerve veins in oral and maxillofacial region is very rich and connected with many parts of the body. Once the infection occurs...
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Predicting Oral Beta-lactam susceptibilities against Streptococcus pneumoniae
BackgroundOral beta-lactam antimicrobials are not routinely tested against Streptococcus pneumoniae due to presumed susceptibility based upon...
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Third-generation cephalosporin resistant gram-negative bacteraemia in patients with haematological malignancy; an 11-year multi-centre retrospective study
ObjectivesAmong patients with haematological malignancy, bacteraemia is a common complication during chemotherapy-induced neutropenia. Resistance of...
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Effectiveness of postoperative oral administration of cephalexin and metronidazole on surgical site infection among obese women undergoing cesarean section: a randomized, double-blind, placebo-controlled, parallel-group study—phase III
BackgroundCesarean section (CS) is the most frequently performed surgery in the United States. Compared to vaginal delivery, CS has a higher risk of...
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Oral quinolones versus intravenous β-lactam for the treatment of acute focal bacterial nephritis: a retrospective cohort study
BackgroundEvidence regarding the best antibiotic regimen and the route of administration to treat acute focal bacterial nephritis (AFBN) is scarce....
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A Comparative Study on Management of Acute Otitis Externa with and Without Oral Antibiotics in a Tertiary Care Centre, Maduranthagam
Acute otitis externa also called as “Swimmers ear” is commonly seen in all age groups. It is a very common condition, severely painful, characterised...
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Oral Antibiotics in Clinical Development for Community-Acquired Urinary Tract Infections
The treatment of urinary tract infections (UTIs) has been complicated by the emergence of multidrug-resistant, β-lactamase-expressing pathogens. As a...
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Oral challenge vs routine care to assess low-risk penicillin allergy in critically ill hospital patients (ORACLE): a pilot safety and feasibility randomised controlled trial
PurposeCritically ill patients are vulnerable to penicillin allergy labels that may be incorrect. The validity of skin testing in intensive care...
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Oral COVID-19 Antiviral Agents in Dermatology Outpatient Treatment
Nirmatrelvir-ritonavir (NMV/r) and molnupiravir are used to treat mild-to-moderate COVID-19 infection in outpatients. However, the use of NMV/r is... -
Effectiveness of oral cephalexin in antibiotic-course completion for methicillin-susceptible Staphylococcus aureus-induced bacteremic vertebral osteomyelitis
BackgroundMethicillin-susceptible Staphylococcus aureus (MSSA) is the most common causative microorganism of pyogenic vertebral osteomyelitis (PVO)....
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Identifying the Best Initial Oral Antibiotics for Adults with Community-Acquired Pneumonia: A Network Meta-Analysis
BackgroundThe objective of this network meta-analysis was to compare rates of clinical response and mortality for empiric oral antibiotic regimens in...
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Streptococcus cristatus bacteremia in a patient with poor oral hygiene: a case report
BackgroundStreptococcus cristatus is a member of the Mitis streptococcus group. Like other members of this group, it resides on mucosal surfaces of...
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Drug-Induced Oral Ulcers
Drug-induced oral ulcers may be unique or multiple and are usually painful. They vary in localization, depth and extent depending on the direct or...