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Amniotic Fluid Embolism
Amniotic fluid embolism is one of the most devastating complications in obstetrics. Intensivists are often called upon to co-manage cases of... -
Amniotic Fluid Embolism
Amniotic fluid embolism (AFE) is one of the obstetric emergency with pathogenic mystery, diagnostic difficulty and therapeutic challenges. -
Immunophenotyping of Leukocytes in Amniotic Fluid
Immunophenotyping allows for the deep characterization of leukocytes present in biological samples. Here, we describe a complete procedure for the... -
Tanshinone IIA changed the amniotic fluid volume and regulated expression of AQP1 and AQP3 in amniotic epithelium cells: a promising drug treating abnormal amniotic fluid volume
BackgroundMany studies have confirmed the association of aquaporins (AQPs) with abnormal amniotic fluid volume (AFV). In our previous experiments, we...
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Amniotic Fluid Embolism
Amniotic fluid embolism (AFE)Amniotic Fluid Embolism (AFE) is a rare (incidence approximately 1 in 60,000) [1], but potentially catastrophic... -
The amniotic fluid proteome changes across gestation in humans and rhesus macaques
Amniotic fluid is a complex biological medium that offers protection to the fetus and plays a key role in normal fetal nutrition, organogenesis, and...
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Amniotic Fluid Embolism (Adult)
Amniotic fluid embolism is a rare but dreaded complication that can occur during labor and delivery or during a cesarean section. It has the... -
Immersed in a reservoir of potential: amniotic fluid-derived extracellular vesicles
This review aims to encapsulate the current knowledge in extracellular vesicles extracted from amniotic fluid and amniotic fluid derived stem/stromal...
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Amniotic Fluid Proteomics Analysis and In Vitro Validation to Identify Potential Biomarkers of Preterm Birth
This study aimed to investigate the regulation of amniotic fibroblast (AFC) function by vitamin K–dependent protein Z (PROZ) during preterm birth...
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Identification of protein biomarkers associated with congenital diaphragmatic hernia in human amniotic fluid
Congenital diaphragmatic hernia (CDH) is a severe birth defect frequently associated with pulmonary hypoplasia, pulmonary hypertension, and heart...
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The amniotic fluid proteome changes with term labor and informs biomarker discovery in maternal plasma
The intra-uterine components of labor, namely, myometrial contractility, cervical ripening, and decidua/membrane activation, have been extensively...
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Fetal biometry and amniotic fluid volume assessment end-to-end automation using Deep Learning
Fetal biometry and amniotic fluid volume assessments are two essential yet repetitive tasks in fetal ultrasound screening scans, aiding in the...
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Soluble urokinase plasminogen activator receptor in vaginally collected amniotic fluid predicting fetal inflammatory response syndrome: a prospective cohort study
BackgroundImproving noninvasive antenatal diagnosis of fetal inflammatory response syndrome (FIRS) can assist in the evaluation of prenatal risk and...
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Amniotic fluid content in children with kidney and urinary tract anomalies determines pre- and postnatal development
BackgroundRenal oligohydramnios (ROH) describes an abnormally low volume of amniotic fluid (AF) during pregnancy. ROH is mostly caused by congenital...
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Disorders of Amniotic Fluid Volume: Oligoamnios and Polyhydramnios
Amniotic Fluid (LA) is a complex of necessary and essential substances for the complete development of intrauterine life. Alterations in amniotic... -
Evolutionary bridges: how factors present in amniotic fluid and human milk help mature the gut
Necrotizing enterocolitis (NEC) continues to be a leading cause of morbidity and mortality in preterm infants. As modern medicine significantly...
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Microbial signatures in amniotic fluid at preterm birth and association with bronchopulmonary dysplasia
BackgroundMicrobiome dysbiosis can have long-lasting effects on our health and induce the development of various diseases. Bronchopulmonary dysplasia...
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Volatile Organic Compounds Detected in Amniotic Fluid of Women During Normal Pregnancy
Exposure to volatile organic compounds (VOCs) during the fetal period may induce negative effects on children’s health (e.g. increased risk of low...
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Comprehensive human amniotic fluid metagenomics supports the sterile womb hypothesis
As metagenomic approaches for detecting infectious agents have improved, each tissue that was once thought to be sterile has been found to harbor a...
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Transitional Hemodynamics in Neonates Born Through Meconium-Stained Amniotic Fluid: A Prospective Observational Study
Neonates born through meconium-stained amniotic fluid (MSAF) are at increased risk of altered cardiopulmonary transition at birth. There is a paucity...