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Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1

  • Diagnostic Neuroradiology
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Abstract

We describe a case of cerebellar pleomorphic xanthoastrocytoma (PXA) occurring in a patient with neurofibromatosis type 1 (NF1). The histomorphology of this uncommon glial (astrocytic) neoplasm is discussed. The occurrence of this tumor within the posterior fossa is extremely rare. To our knowledge, this is the first reported case of a cerebellar PXA in a patient with NF1.

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References

  1. Evan AJ, Fayaz I, Cusimano MD, et al. Combined pleomorphic xanthoastrocytoma-ganglioglioma of the cerebellum. Arch Pathol Lab Med 2000; 124:1707–1709.

    Google Scholar 

  2. Giannini C, Scheithauer BW, Burger PC, et al. Pleomorphic xanthoastrocytoma: what do we really know about it? Cancer 1999; 85:2033–2045.

    Google Scholar 

  3. Glasser RS, Rojiani AM, Mickle P, et al. Delayed occurrence of cerebellar pleomorphic xanthoastrocytoma after supratentorial pleomorphic xanthoastrocytoma removal. J Neurosurg 1995; 82:116–118.

    Google Scholar 

  4. Ilgren EB, Kinnier-Wilson LM, Stiller CA. Gliomas in neurofibromatosis: a series of 89 cases. Pathol Annu 1985; 20:331–358.

    Google Scholar 

  5. Kepes JJ, Rubinstein LJ, Eng LF. Pleomorphic xanthoastrocytoma: a distinctive meningocerebral glioma of young subjects with relatively favorable prognosis. A study of 12 cases. Cancer 1979; 44:1839–1852.

    Google Scholar 

  6. Koeller KK, Henry JM. From the archives of the AFIP: superficial gliomas: radiologic-pathologic correlation. Radiographics 2001; 21:1533–1556.

    Google Scholar 

  7. Korf BR. Malignancy in neurofibromatosis type 1. Oncologist 2000; 5:477-485.

    Google Scholar 

  8. Kubo O, Sasahara A, Tajika Y, et al. Pleomorphic xanthoastrocytoma with neurofibromatosis type 1: case report. Brain Tumor Pathol 1996; 13: 79–83.

    Google Scholar 

  9. Lim SC, Jang SJ, Kim YS. Cerebellar pleomorphic xanthoastrocytoma in an infant. Pathology Int 1999; 49:811–815.

    Google Scholar 

  10. Lindboe CF, Cappelen J, Kepes JJ. Pleomorphic xanthoastrocytoma as a component of a cerebellar ganglioma: case report. Neurosurgery 1992; 31:353–355.

    Google Scholar 

  11. Listernick R, Charrow J, Gutmann DH. Intracranial gliomas in neurofibromatosis type 1. Am J Med Genet 1999; 89: 38–44.

    Google Scholar 

  12. Ohta S, Ryu H, Miura K. Eighteen-year survival of a patient with malignant pleomorphic xanthoastrocytoma associated with von Recklinghausen neurofibromatosis. Br J Neurosurg 1999; 13:420–422.

    Google Scholar 

  13. Ozek MM, Sab A, Pamir MN, et al. Pleomorphic xanthoastrocytoma associated with von Recklinghausen nerurofibromatosis. Childs Nerv Syst 1993; 9:39–42.

    Google Scholar 

  14. Perry A, Giannini C, Scheithauer BW, et al. Composite pleomorphic xanthoastrocytoma and ganglioglioma: report of four cases and review of the literature. Am J Surg Pathol 1997; 21:763–771.

    Google Scholar 

  15. Rosemberg S, Rotta JM, Yassuda A, et al. Pleomorphic xanthoastrocytoma of the cerebellum. Clin Neuropathol 2000; 19:238–242.

    Google Scholar 

  16. Tien RD, Cardenas CA, Rajagopalan S. Pleomorphic xanthoastrocytoma of the brain: MR findings in six patients. AJR Am J Roentgenol 1992; 159:1287–1290.

    Google Scholar 

  17. Washdahl DA, Scheithauer BW, Andrews BT, et al. Cerebellar pleomorphic xanthoastrocytoma: case report. Neurosurgery 1994; 35:947–951.

    Google Scholar 

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Correspondence to M. J. Naidich.

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Naidich, M.J., Walker, M.T., Gottardi-Littell, N.R. et al. Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1. Neuroradiology 46, 825–829 (2004). https://doi.org/10.1007/s00234-004-1216-0

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  • DOI: https://doi.org/10.1007/s00234-004-1216-0

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