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Hepatitis: Difference between revisions

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reworked =Toxic=
m =Drug induced hepatits=
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=== Drug induced hepatits ===
A large number of drugs can cause hepatitis, including the very commonly used [[statin]]s. The [[anti-diabetic drug]] [[troglitazone]] was withdrawn in [[2000]] for causing hepatitis. Other drugs associated with hepatitis[http://www.healthatoz.com/healthatoz/Atoz/dc/caz/infc/hepa/hepres.html]:
* [[Halothane]] (a specific type of anesthetic gas)
* [[Methyldopa]] ([[antihypertensive]])
* [[Isoniazid]] (INH) and [[rifampicin]] ([[tuberculosis]]-specific [[antibiotic]]s)
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* Some herbs and nutritional supplements
The clinical course of drug induced hepatitis is quite variable, depending on the drug and the patient's tendency to react to the drug. For example, halothane hepatits can range from mild to fatal as can INH induced hepatitis. Oral contraceptives can cause structural changes in the liver. Amiodarone hepatitis can be untreatable since the long half life of the drug means that there is no effective way to stop exposure to the drug. Statins can cause elevations of liver function blood tests normally without indicating an underlying hepatitis. Lastly, human variability is such that any drug can be a cause of hepatitis.
 
=== Other toxins that cause hepatis ===
Toxins and drugs can cause hepatitis: