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'''Hepatitis''' is [[inflammation]] of the [[liver parenchyma|liver tissue]].<ref name=NIH2016>{{cite web|title=Hepatitis|url=https://www.niaid.nih.gov/diseases-conditions/hepatitis|website=NIAID|access-date=2 November 2016|url-status=live|archive-url=https://web.archive.org/web/20161104002228/https://www.niaid.nih.gov/diseases-conditions/hepatitis|archive-date=4 November 2016}}</ref><ref name="MedlinePlus 2020">{{cite web | title=Hepatitis | website=MedlinePlus | date=2020-05-20 | url=https://medlineplus.gov/hepatitis.html | access-date=2020-07-19 | quote=Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons. Hepatitis is an inflammation of the liver.}}</ref> Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes ([[jaundice]]), [[Anorexia (symptom)|poor appetite]], [[vomiting]], [[fatigue (medicine)|tiredness]], [[abdominal pain]], and [[diarrhea]].<ref name=MedLine2016/><ref name=WHO2016QA/> Hepatitis is ''[[acute (medicine)|acute]]'' if it resolves within six months, and ''[[chronic condition|chronic]]'' if it lasts longer than six months.<ref name=MedLine2016>{{cite web|title=Hepatitis|url=https://medlineplus.gov/hepatitis.html|website=MedlinePlus|access-date=10 November 2016|url-status=live|archive-url=https://web.archive.org/web/20161111061624/https://medlineplus.gov/hepatitis.html|archive-date=11 November 2016}}</ref><ref>{{cite web|title=Hepatitis (Hepatitis A, B, and C) {{!}} ACG Patients|url=http://patients.gi.org/topics/viral-hepatitis/|website=patients.gi.org|url-status=live|archive-url=https://web.archive.org/web/20170223163352/http://patients.gi.org/topics/viral-hepatitis/|archive-date=2017-02-23}}</ref> Acute hepatitis can [[self-limiting (biology)|resolve on its own]], progress to chronic hepatitis, or (rarely) result in [[acute liver failure]].<ref>{{cite journal |author1=Bernal W. |author2=Wendon J. | year = 2013 | title = Acute Liver Failure | journal = New England Journal of Medicine | volume = 369 | issue = 26| pages = 2525–2534 | doi=10.1056/nejmra1208937| pmid=24369077|s2cid=205116503 | doi-access = free }}</ref> Chronic hepatitis may progress to scarring of the liver ([[cirrhosis]]), [[liver failure]], and [[liver cancer]].<ref name=NIH2016/><ref>{{Cite web |title=Esto es la hepatitis: Conócela, enfréntate a ella |url=https://www.infoterio.com/2022/08/Esto-es-la-hepatitis-Conocela-enfrentate-a-ella.html |access-date=2023-02-12 |website=Infoterio Noticias {{!}} Ciencia y Tecnología |date=8 August 2022 |language=es}}</ref>
Hepatitis is most commonly caused by the virus ''[[hepatovirus A]]'', ''[[hepatitis B virus|B]]'', ''[[hepatitis C virus|C]]'', ''[[hepatitis D virus|D]]'', and ''[[hepatitis E virus|E]]''.<ref name=WHO2016QA>{{cite web|title=What is hepatitis?|url=https://www.who.int/features/qa/76/en/|website=WHO|access-date=10 November 2016|date=July 2016|url-status=live|archive-url=https://web.archive.org/web/20161107003115/http://www.who.int/features/qa/76/en/|archive-date=7 November 2016}}</ref><ref name=NIH2016/> Other [[Viral hepatitis|viruses can also cause liver inflammation]], including [[cytomegalovirus]], [[Epstein–Barr virus]], and [[Yellow fever|yellow fever virus]]. Other common causes of hepatitis include [[alcoholism|heavy alcohol use]], certain medications, toxins, other infections, [[autoimmune diseases]],<ref name=WHO2016QA/><ref name=NIH2016/> and [[non-alcoholic steatohepatitis]] (NASH).<ref name=NASH2014>{{cite web|title=Fatty Liver Disease (Nonalcoholic Steatohepatitis) |url=https://www.niddk.nih.gov/health-information/health-topics/liver-disease/nonalcoholic-steatohepatitis/pages/facts.aspx |website=NIDDK |access-date=10 November 2016 |date=May 2014 |archive-url=https://web.archive.org/web/20161111061658/https://www.niddk.nih.gov/health-information/health-topics/liver-disease/nonalcoholic-steatohepatitis/pages/facts.aspx |archive-date=11 November 2016 |url-status=dead }}</ref> Hepatitis A and E are mainly spread by contaminated food and water.<ref name=NIH2016/> Hepatitis B is mainly [[sexually transmitted infection|sexually transmitted]], but may also be [[vertically transmitted infection|passed from mother to baby]] during [[pregnancy]] or [[childbirth]] and spread through infected [[blood]].<ref name=NIH2016/> Hepatitis C is commonly spread through infected blood such as may occur during [[needle sharing]] by [[drug injection|intravenous drug users]].<ref name=NIH2016/> Hepatitis D can only infect people already infected with hepatitis B.<ref name=NIH2016/>
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====Hepatitis C====
Hepatitis C infections each year had been declining since the 1980s, but began to increase again in 2006.<ref>{{Cite web|url=https://www.cdc.gov/hepatitis/statistics/2013surveillance/commentary.htm|title=Commentary {{!}} U.S. 2013 Surveillance Data for Viral Hepatitis {{!}} Statistics & Surveillance {{!}} Division of Viral Hepatitis {{!}} CDC|website=www.cdc.gov|access-date=2016-03-09|url-status=live|archive-url=https://web.archive.org/web/20160305151134/http://www.cdc.gov/hepatitis/statistics/2013surveillance/commentary.htm|archive-date=2016-03-05}}</ref> The data are unclear as to whether the decline can be attributed to [[needle exchange programme]]s.<ref>Wright NMJ, Millson CE, Tompkins CNE (2005). What is the evidence for the effectiveness of interventions to reduce hepatitis C infection and the associated morbidity? Copenhagen, WHO Regional Office for Europe (Health Evidence Network report; {{cite web |url=http://www.euro.who.int/document/E86159.pdf |title=
====Alcoholic hepatitis====
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