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User:Mr. Ibrahem/Delafloxacin

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This is the current revision of this page, as edited by Mr. Ibrahem (talk | contribs) at 10:18, 16 May 2024 (from https://mdwiki.org/wiki/Delafloxacin). The present address (URL) is a permanent link to this version.

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Mr. Ibrahem/Delafloxacin
Clinical data
Trade namesBaxdela, Quofenix
Other namesDelafloxacin meglumine; ABT-492; RX-3341; WQ-3034
AHFS/Drugs.comMonograph
License data
Routes of
administration
By mouth, intravenous injection
Drug classFluoroquinolone[1]
Legal status
Legal status
  • US: ℞-only
  • EU: Rx-only
  • In general: ℞ (Prescription only)
Identifiers
  • 1-(6-amino-3,5-difluoro-2-pyridyl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-quinoline-3-carboxylic acid
Chemical and physical data
FormulaC18H12ClF3N4O4
Molar mass440.76 g·mol−1
3D model (JSmol)
  • Fc4cc(F)c(nc4N1\C=C(\C(=O)O)C(=O)c2c1c(Cl)c(c(F)c2)N3CC(O)C3)N

Delafloxacin sold under the brand name Baxdela among others, is an antibiotic used to treat bacterial skin and skin structure infections.[2] It is generally effective for MRSA and Pseudomonas.[1] It may be given by mouth or by injection into a vein.[2]

Common side effects include diarrhea and nausea.[2] Other side effects may include tendinitis, peripheral neuropathy, psychosis, Clostridioides difficile infection, and anaphylaxis.[1] Safety in pregnancy is unclear.[1] It is a fluoroquinolone.[1]

Delafloxacin was approved for medical use in the United States in 2017 and Europe in 2019.[1][2] In the United Kingdom five days of treatment costs the NHS about £615 as of 2021.[3] This amount in the United States is about 760 USD.[4]

References[edit]

  1. ^ a b c d e f g "Delafloxacin Monograph for Professionals". Drugs.com. Archived from the original on 21 January 2021. Retrieved 22 December 2021.
  2. ^ a b c d e "Quofenix EPAR". European Medicines Agency (EMA). 16 October 2019. Archived from the original on 5 August 2020. Retrieved 12 May 2020. Public Domain This article incorporates text from this source, which is in the public domain.
  3. ^ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 595. ISBN 978-0857114105.
  4. ^ "Baxdela Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 22 December 2021.