TRAF1: Difference between revisions

'''TNF receptor-associated factor 1''' is a [[protein]] that in humans is encoded by the ''TRAF1'' [[gene]].<ref name="pmid8069916">{{cite journal | author = Rothe M, Wong SC, Henzel WJ, Goeddel DV | title = A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor | journal = Cell | volume = 78 | issue = 4 | pages = 681–92 | year = 1994 | month = Sep | pmid = 8069916 | pmc = | doi =10.1016/0092-8674(94)90532-0 }}</ref>

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TRAF1 has been shown to [[Protein-protein interaction|interact]] with [[CD30]],<ref name=pmid8943059>{{cite journal |doi=10.1073/pnas.93.24.14053 |last=Ansieau |first=S |authorlink= |coauthors=Scheffrahn I, Mosialos G, Brand H, Duyster J, Kaye K, Harada J, Dougall B, Hübinger G, Kieff E, Herrmann F, Leutz A, Gruss H J |year=[[1996]]|month=Nov. |title=Tumor necrosis factor receptor-associated factor (TRAF)-1, TRAF-2, and TRAF-3 interact in vivo with the CD30 cytoplasmic domain; TRAF-2 mediates CD30-induced nuclear factor kappa B activation |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=93 |issue=24 |pages=14053–8 |publisher= |location = UNITED STATES| issn = 0027-8424| pmid = 8943059 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=19493 }}</ref> [[CFLAR]],<ref name=pmid9208847>{{cite journal |doi=10.1016/S1074-7613(00)80450-1 |last=Shu |first=H B |authorlink= |coauthors=Halpin D R, Goeddel D V |year=[[1997]]|month=Jun. |title=Casper is a FADD- and caspase-related inducer of apoptosis |journal=Immunity |volume=6 |issue=6 |pages=751–63 |publisher= |location = UNITED STATES| issn = 1074-7613| pmid = 9208847 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid10837247>{{cite journal |doi=10.1016/S0960-9822(00)00512-1 |last=Kataoka |first=T |authorlink= |coauthors=Budd R C, Holler N, Thome M, Martinon F, Irmler M, Burns K, Hahne M, Kennedy N, Kovacsovics M, Tschopp J |year=[[2000]]|month=Jun. |title=The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways |journal=Curr. Biol. |volume=10 |issue=11 |pages=640–8 |publisher= |location = ENGLAND| issn = 0960-9822| pmid = 10837247 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[Baculoviral IAP repeat-containing protein 3]],<ref name=pmid9384571>{{cite journal |last=Roy |first=N |authorlink= |coauthors=Deveraux Q L, Takahashi R, Salvesen G S, Reed J C |year=[[1997]]|month=Dec. |title=The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases |journal=EMBO J. |volume=16 |issue=23 |pages=6914–25 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 9384571 |doi = 10.1093/emboj/16.23.6914 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1170295 }}</ref><ref name=pmid11907583>{{cite journal |last=Li |first=Xiaoming |authorlink= |coauthors=Yang Yili, Ashwell Jonathan D |year=[[2002]]|month=Mar. |title=TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2 |journal=[[Nature (journal)|Nature]] |volume=416 |issue=6878 |pages=345–7 |publisher= |location = England| issn = 0028-0836| pmid = 11907583 |doi = 10.1038/416345a | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[BIRC2]],<ref name=pmid9384571/><ref name=pmid11907583/><ref name=pmid8943045>{{cite journal |doi=10.1073/pnas.93.24.13973 |last=Shu |first=H B |authorlink= |coauthors=Takeuchi M, Goeddel D V |year=[[1996]]|month=Nov. |title=The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=93 |issue=24 |pages=13973–8 |publisher= |location = UNITED STATES| issn = 0027-8424| pmid = 8943045 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=19479 }}</ref> [[Caspase 8]],<ref name=pmid12887920>{{cite journal |doi=10.1016/S0092-8674(03)00521-X |last=Micheau |first=Olivier |authorlink= |coauthors=Tschopp Jürg |year=[[2003]]|month=Jul. |title=Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes |journal=Cell |volume=114 |issue=2 |pages=181–90 |publisher= |location = United States| issn = 0092-8674| pmid = 12887920 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid11098060>{{cite journal |last=Leo |first=E |authorlink= |coauthors=Deveraux Q L, Buchholtz C, Welsh K, Matsuzawa S, Stennicke H R, Salvesen G S, Reed J C |year=[[2001]]|month=Mar. |title=TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis |journal=J. Biol. Chem. |volume=276 |issue=11 |pages=8087–93 |publisher= |location = United States| issn = 0021-9258| pmid = 11098060 |doi = 10.1074/jbc.M009450200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[HIVEP3]],<ref name=pmid11804591>{{cite journal |doi=10.1016/S1097-2765(01)00434-8 |last=Oukka |first=Mohamed |authorlink= |coauthors=Kim Sean T, Lugo Geancarlo, Sun Jenny, Wu Lai-Chu, Glimcher Laurie H |year=[[2002]]|month=Jan. |title=A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2 |journal=Mol. Cell |volume=9 |issue=1 |pages=121–31 |publisher= |location = United States| issn = 1097-2765| pmid = 11804591 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[TNFAIP3]],<ref name=pmid8692885>{{cite journal |doi=10.1073/pnas.93.13.6721 |last=Song |first=H Y |authorlink= |coauthors=Rothe M, Goeddel D V |year=[[1996]]|month=Jun. |title=The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=93 |issue=13 |pages=6721–5 |publisher= |location = UNITED STATES| issn = 0027-8424| pmid = 8692885 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=39093 }}</ref><ref name=pmid9928991>{{cite journal |doi=10.1016/S0014-5793(98)01645-7 |last=Heyninck |first=K |authorlink= |coauthors=Beyaert R |year=[[1999]]|month=Jan. |title=The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6 |journal=FEBS Lett. |volume=442 |issue=2-3 |pages=147–50 |publisher= |location = NETHERLANDS| issn = 0014-5793| pmid = 9928991 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[TRAF2]],<ref name=pmid14743216>{{cite journal |last=Bouwmeester |first=Tewis |authorlink= |coauthors=Bauch Angela, Ruffner Heinz, Angrand Pierre-Olivier, Bergamini Giovanna, Croughton Karen, Cruciat Cristina, Eberhard Dirk, Gagneur Julien, Ghidelli Sonja, Hopf Carsten, Huhse Bettina, Mangano Raffaella, Michon Anne-Marie, Schirle Markus, Schlegl Judith, Schwab Markus, Stein Martin A, Bauer Andreas, Casari Georg, Drewes Gerard, Gavin Anne-Claude, Jackson David B, Joberty Gerard, Neubauer Gitte, Rick Jens, Kuster Bernhard, Superti-Furga Giulio |year=[[2004]]|month=Feb. |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway |journal=Nat. Cell Biol. |volume=6 |issue=2 |pages=97–105 |publisher= |location = England| issn = 1465-7392| pmid = 14743216 |doi = 10.1038/ncb1086 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid8702708>{{cite journal |doi=10.1074/jbc.271.33.19935 |last=Takeuchi |first=M |authorlink= |coauthors=Rothe M, Goeddel D V |year=[[1996]]|month=Aug. |title=Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins |journal=J. Biol. Chem. |volume=271 |issue=33 |pages=19935–42 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 8702708 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[RANK]]<ref name=pmid9852070>{{cite journal |doi=10.1074/jbc.273.51.34120 |last=Galibert |first=L |authorlink= |coauthors=Tometsko M E, Anderson D M, Cosman D, Dougall W C |year=[[1998]]|month=Dec. |title=The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily |journal=J. Biol. Chem. |volume=273 |issue=51 |pages=34120–7 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9852070 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid10025951>{{cite journal |doi=10.1016/S0014-5793(98)01731-1 |last=Kim |first=H H |authorlink= |coauthors=Lee D E, Shin J N, Lee Y S, Jeon Y M, Chung C H, Ni J, Kwon B S, Lee Z H |year=[[1999]]|month=Jan. |title=Receptor activator of NF-kappaB recruits multiple TRAF family adaptors and activates c-Jun N-terminal kinase |journal=FEBS Lett. |volume=443 |issue=3 |pages=297–302 |publisher= |location = NETHERLANDS| issn = 0014-5793| pmid = 10025951 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[TRAF interacting protein]].<ref name=pmid9104814>{{cite journal |doi=10.1084/jem.185.7.1275 |last=Lee |first=S Y |authorlink= |coauthors=Lee S Y, Choi Y |year=[[1997]]|month=Apr. |title=TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation |journal=J. Exp. Med. |volume=185 |issue=7 |pages=1275–85 |publisher= |location = UNITED STATES| issn = 0022-1007| pmid = 9104814 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=2196258 }}</ref>

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