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Chemical Pregnanes

These diseases are associated with Pregnanes or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Disease categories [Show chart]

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Disease category
Association type
1–50 of 33,679 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Progesterone Liver Cirrhosis, Experimental M
387 genes view node 		507.42 86
2. Desoxycorticosterone Acetate Hypertension M
40 genes view node 		128.82 67
3. Hydrocortisone Obesity M
42 genes view node 		91.82 42
4. Aldosterone Hypertension M
36 genes view node 		87.41 224
Has associated exposure references.
5. Dexamethasone Myocardial Ischemia M
133 genes view node 		85.07 23
6. Aldosterone Heart Failure M
28 genes view node 		78.14 51
Has associated exposure references.
7. Progesterone Disease Models, Animal M
109 genes view node 		77.34 74
8. Hydrocortisone Hypertension M
52 genes view node 		72.71 240
Has associated exposure references.
9. Hydrocortisone Heart Failure M
40 genes view node 		70.19 42
Has associated exposure references.
10. Progesterone Polycystic Ovary Syndrome M
60 genes view node 		65.81 14
11. Corticosterone Hypertension M
46 genes view node 		64.33 228
12. Aldosterone Diabetes Mellitus, Experimental M
18 genes view node 		56.26 24
13. Dexamethasone Craniofacial Abnormalities M
88 genes view node 		52.51 112
14. Corticosterone Disease Models, Animal M
28 genes view node 		45.81 30
15. Aldosterone Myocardial Infarction M
18 genes view node 		44.39 54
16. Budesonide Carcinoma, Hepatocellular M
21 genes view node 		42.75 37
17. Medroxyprogesterone Acetate Adenocarcinoma M
24 genes view node 		42.69 29
18. Medroxyprogesterone Acetate Myocardial Infarction M
27 genes view node 		39.08 67
19. Progesterone Chemical and Drug Induced Liver Injury M
203 genes view node 		38.47 115
20. Medroxyprogesterone Acetate Chemical and Drug Induced Liver Injury M
49 genes view node 		36.99 43
21. Aldosterone Cardiomegaly M
14 genes view node 		36.59 49
22. Dexamethasone Headache M
2 genes view node 		35.84 6
23. Aldosterone Liver Cirrhosis M
14 genes view node 		35.35 22
24. Corticosterone Nerve Degeneration M
24 genes view node 		34.71 33
25. Hydrocortisone Cardiomegaly M
20 genes view node 		32.28 49
26. Progesterone Liver Cirrhosis, Biliary M
26 genes view node 		32.25 10
27. Desoxycorticosterone Cardiomegaly M
11 genes view node 		32.23 47
28. Medroxyprogesterone Acetate Mammary Neoplasms, Experimental M
20 genes view node 		32.18 15
29. Spironolactone Chemical and Drug Induced Liver Injury M
30 genes view node 		31.38 43
30. Prednisolone Carcinoma, Hepatocellular M
28 genes view node 		30.77 33
31. Desoxycorticosterone Acute Kidney Injury M
13 genes view node 		30.38 23
32. Cortisone Hypertension M
13 genes view node 		30.27 23
33. Pregnenolone Carbonitrile Liver Neoplasms M
49 genes view node 		30.05 40
34. Aldosterone Fibrosis M
12 genes view node 		29.64 23
Has associated exposure references.
35. Hydrocortisone Dermatitis, Contact M
15 genes view node 		29.05 3
36. Aldosterone Acute Kidney Injury M
15 genes view node 		29.04 21
37. Medroxyprogesterone Acetate Mammary Neoplasms, Animal M
16 genes view node 		28.40 10
38. Prednisolone Sepsis M
13 genes view node 		26.01 11
39. Aldosterone Stroke M
9 genes view node 		24.23 71
40. Cyproterone Acetate Carcinoma, Hepatocellular M
14 genes view node 		22.99 17
41. Hydrocortisone Essential Hypertension M
8 genes view node 		22.66 4
42. Prednisolone Hypertension M
27 genes view node 		22.61 111
43. Dexamethasone Bradycardia M
17 genes view node 		21.79 26
Has associated exposure references.
44. Hydrocortisone Insulin Resistance M
16 genes view node 		21.78 26
45. Budesonide Chemical and Drug Induced Liver Injury M
19 genes view node 		21.39 29
46. Desoxycorticosterone Acetate Cardiomegaly M
8 genes view node 		21.18 11
47. Desoxycorticosterone Stroke M
7 genes view node 		21.03 6
48. Aldosterone Kidney Diseases M
13 genes view node 		20.72 31
49. Dexamethasone Osteoporosis M
44 genes view node 		20.67 32
50. Desoxycorticosterone Proteinuria M
8 genes view node 		20.67 14
1–50 of 33,679 results.
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