1. |
11-dehydrocorticosterone
|
regulation of metabolic process
|
Cisplatin
|
[Cisplatin affects regulation of metabolic process] which results in increased abundance of 11-dehydrocorticosterone |
1: Rattus norvegicus |
Kidney
|
|
1 |
2. |
11-dehydrocorticosterone
|
steroid metabolic process
|
Heroin
|
[Heroin affects steroid metabolic process] which results in decreased abundance of 11-dehydrocorticosterone |
1: Mus musculus |
Liver
|
2 genes
|
1 |
3. |
11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol
|
myotube differentiation
|
Estradiol
|
11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol inhibits the reaction [Estradiol affects myotube differentiation] |
1: Mus musculus |
Muscle Cells
| Cell Line
|
|
1 |
4. |
11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol
|
myotube differentiation
|
Albuterol
|
11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol inhibits the reaction [Albuterol affects myotube differentiation] |
1: Mus musculus |
Muscle Cells
| Cell Line
|
|
1 |
5. |
11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol
|
myotube differentiation
|
Formoterol Fumarate
|
11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol inhibits the reaction [Formoterol Fumarate affects myotube differentiation] |
1: Mus musculus |
Muscle Cells
| Cell Line
|
|
1 |
6. |
11-hydroxyprogesterone
|
regulation of metabolic process
|
Soot
|
[Soot affects regulation of metabolic process] which results in decreased abundance of 11-hydroxyprogesterone |
1: Rattus norvegicus |
Serum
|
|
1 |
7. |
11-hydroxyprogesterone 11-glucuronide
|
regulation of cellular metabolic process
|
deoxynivalenol
|
[deoxynivalenol affects regulation of cellular metabolic process] which results in decreased abundance of 11-hydroxyprogesterone 11-glucuronide |
1: Sus scrofa |
Intestinal Mucosa
| Cell Line
|
|
1 |
8. |
11-ketotestosterone
|
androgen receptor signaling pathway
|
|
11-ketotestosterone results in increased androgen receptor signaling pathway |
1: Gnathopogon caerulescens |
Sertoli Cells
|
1 gene
|
1 |
9. |
11-ketotestosterone
|
locomotory behavior
|
|
11-ketotestosterone affects locomotory behavior |
1: Danio rerio |
|
|
1 |
10. |
11-ketotestosterone
|
androgen metabolic process
|
bisphenol A
|
[bisphenol A affects androgen metabolic process] which results in increased abundance of 11-ketotestosterone |
1: Gobiocypris rarus |
Tissues
|
1 gene
|
1 |
11. |
11-ketotestosterone
|
steroid biosynthetic process
|
bisphenol A
|
[bisphenol A affects steroid biosynthetic process] which results in decreased abundance of 11-ketotestosterone |
1: Sparus aurata |
Plasma
|
|
1 |
12. |
11-ketotestosterone
|
testosterone biosynthetic process
|
Acetaminophen
|
[Acetaminophen affects testosterone biosynthetic process] which results in decreased abundance of 11-ketotestosterone |
1: Danio rerio |
Testis
|
|
1 |
13. |
11-ketotestosterone
|
negative regulation of androgen secretion
|
bisphenol A
|
[bisphenol A results in increased negative regulation of androgen secretion] which results in decreased secretion of 11-ketotestosterone |
1: Amphiprion ocellaris |
Serum
|
|
1 |
14. |
11-ketotestosterone
|
negative regulation of androgen secretion
|
Ethinyl Estradiol
|
[Ethinyl Estradiol results in increased negative regulation of androgen secretion] which results in decreased abundance of 11-ketotestosterone |
1: Amphiprion ocellaris |
Serum
|
|
1 |
15. |
11-ketotestosterone
|
steroid metabolic process
|
4,4'-hexafluorisopropylidene diphenol
|
[4,4'-hexafluorisopropylidene diphenol affects steroid metabolic process] which results in increased secretion of 11-ketotestosterone |
1: Danio rerio |
Gonads
|
1 gene
|
1 |
16. |
16-hydroxyandrost-4-en-3,17-dione
|
steroid biosynthetic process
|
Colforsin
|
[Colforsin results in increased steroid biosynthetic process] which results in increased secretion of 16-hydroxyandrost-4-en-3,17-dione |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
|
1 |
17. |
16-hydroxyestrone
|
estrogen biosynthetic process
|
Fingolimod Hydrochloride
|
[Fingolimod Hydrochloride affects estrogen biosynthetic process] which results in decreased secretion of 16-hydroxyestrone |
1: Homo sapiens |
Prostate
| Cell Line, Tumor
|
|
1 |
18. |
17,20-dihydroxy-4-pregnen-3-one
|
androgen receptor signaling pathway
|
|
17,20-dihydroxy-4-pregnen-3-one results in increased androgen receptor signaling pathway |
1: Gnathopogon caerulescens |
Sertoli Cells
|
|
1 |
19. |
17,20-dihydroxy-4-pregnen-3-one
|
steroid biosynthetic process
|
bisphenol A
|
[bisphenol A affects steroid biosynthetic process] which results in increased abundance of 17,20-dihydroxy-4-pregnen-3-one |
1: Sparus aurata |
Plasma
|
|
1 |
20. |
17-alpha-Hydroxypregnenolone
|
C21-steroid hormone metabolic process
|
Ketoconazole
|
[Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
|
1 |
21. |
17-alpha-Hydroxypregnenolone
|
C21-steroid hormone metabolic process
|
Ketoconazole
|
[Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line
|
|
1 |
22. |
17-alpha-Hydroxypregnenolone
|
C21-steroid hormone metabolic process
|
Fluconazole
|
[Fluconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
|
1 |
23. |
17-alpha-Hydroxypregnenolone
|
C21-steroid hormone metabolic process
|
Fluconazole
|
[Fluconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line
|
|
1 |
24. |
17-alpha-Hydroxypregnenolone
|
steroid biosynthetic process
|
Colforsin
|
[Colforsin results in increased steroid biosynthetic process] which results in increased secretion of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
1 gene
|
1 |
25. |
17-alpha-Hydroxypregnenolone
|
negative regulation of steroid hormone biosynthetic process
|
Tramadol
|
[Tramadol results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
|
1 |
26. |
17-alpha-Hydroxypregnenolone
|
steroid biosynthetic process
|
Promethazine
|
[Promethazine affects steroid biosynthetic process] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
1 gene
|
1 |
27. |
17-alpha-Hydroxypregnenolone
|
steroid biosynthetic process
|
Cetirizine
|
[Cetirizine affects steroid biosynthetic process] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
1 gene
|
1 |
28. |
17-alpha-Hydroxypregnenolone
|
steroid biosynthetic process
|
fexofenadine
|
[fexofenadine affects steroid biosynthetic process] which affects the chemical synthesis of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
1 gene
|
1 |
29. |
17-alpha-Hydroxypregnenolone
|
steroid biosynthetic process
|
Atorvastatin
|
[Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
1 gene
|
1 |
30. |
17-alpha-Hydroxypregnenolone
|
steroid biosynthetic process
|
Atorvastatin
|
[Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Rattus norvegicus |
Testis
|
1 gene
|
1 |
31. |
17-alpha-Hydroxypregnenolone
|
steroid biosynthetic process
|
Atorvastatin
|
[Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Rattus norvegicus |
Adrenal Glands
|
1 gene
|
1 |
32. |
17-alpha-Hydroxypregnenolone
|
negative regulation of steroid hormone biosynthetic process
|
Clotrimazole
|
[Clotrimazole results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
|
1 |
33. |
17-alpha-Hydroxypregnenolone
|
regulation of steroid hormone biosynthetic process
|
Ketoconazole
|
[Ketoconazole affects regulation of steroid hormone biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
|
1 |
34. |
17-alpha-Hydroxyprogesterone
|
C21-steroid hormone metabolic process
|
Ketoconazole
|
[Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line
|
1 gene
|
1 |
35. |
17-alpha-Hydroxyprogesterone
|
C21-steroid hormone metabolic process
|
Ketoconazole
|
[Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
1 gene
|
1 |
36. |
17-alpha-Hydroxyprogesterone
|
C21-steroid hormone metabolic process
|
Fluconazole
|
[Fluconazole affects C21-steroid hormone metabolic process] which affects the abundance of 17-alpha-Hydroxyprogesterone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
1 gene
|
1 |
37. |
17-alpha-Hydroxyprogesterone
|
C21-steroid hormone metabolic process
|
Fluconazole
|
[Fluconazole affects C21-steroid hormone metabolic process] which results in increased abundance of 17-alpha-Hydroxyprogesterone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line
|
1 gene
|
1 |
38. |
17-alpha-Hydroxyprogesterone
|
steroid biosynthetic process
|
Colforsin
|
[Colforsin results in increased steroid biosynthetic process] which results in increased secretion of 17-alpha-Hydroxyprogesterone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
3 genes
|
1 |
39. |
17-alpha-Hydroxyprogesterone
|
negative regulation of steroid hormone biosynthetic process
|
Venlafaxine Hydrochloride
|
[Venlafaxine Hydrochloride results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
|
1 |
40. |
17-alpha-Hydroxyprogesterone
|
negative regulation of steroid hormone biosynthetic process
|
Tramadol
|
[Tramadol results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
|
1 |
41. |
17-alpha-Hydroxyprogesterone
|
steroid biosynthetic process
|
Atorvastatin
|
[Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone |
1: Homo sapiens |
Adrenal Cortex
| Cell Line, Tumor
|
3 genes
|
1 |
42. |
17-alpha-Hydroxyprogesterone
|
steroid biosynthetic process
|
Atorvastatin
|
[Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone |
1: Rattus norvegicus |
Testis
|
3 genes
|
1 |
43. |
17-alpha-Hydroxyprogesterone
|
steroid biosynthetic process
|
Atorvastatin
|
[Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone |
1: Rattus norvegicus |
Adrenal Glands
|
3 genes
|
1 |
44. |
17-alpha-Hydroxyprogesterone
|
steroid biosynthetic process
|
Atorvastatin
|
[Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone |
1: Rattus norvegicus |
Plasma
|
3 genes
|
1 |
45. |
17-alpha-Hydroxyprogesterone
|
positive regulation of lipid storage
|
1-Methyl-3-isobutylxanthine
| Dexamethasone
| INS
| Rosiglitazone
|
17-alpha-Hydroxyprogesterone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased positive regulation of lipid storage] |
1: Homo sapiens |
Subcutaneous Fat
| Stem Cells
| Cells, Cultured
|
|
1 |
46. |
17-alpha-Hydroxyprogesterone
|
positive regulation of lipid storage
|
1-Methyl-3-isobutylxanthine
| INS
| Rosiglitazone
|
[17-alpha-Hydroxyprogesterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased positive regulation of lipid storage |
1: Homo sapiens |
Subcutaneous Fat
| Stem Cells
| Cells, Cultured
|
|
1 |
47. |
17-alpha-Hydroxyprogesterone
|
negative regulation of fat cell differentiation
|
1-Methyl-3-isobutylxanthine
| INS
| Rosiglitazone
|
[17-alpha-Hydroxyprogesterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased negative regulation of fat cell differentiation |
1: Homo sapiens |
Subcutaneous Fat
| Stem Cells
| Cells, Cultured
|
2 genes
|
1 |
48. |
17-alpha-Hydroxyprogesterone
|
progesterone metabolic process
|
perfluorooctanoic acid
|
[perfluorooctanoic acid affects progesterone metabolic process] which affects the secretion of 17-alpha-Hydroxyprogesterone |
1: Mus musculus |
Leydig Cells
| Cell Line, Tumor
|
2 genes
|
1 |
49. |
17-alpha-Hydroxyprogesterone
|
positive regulation of steroid biosynthetic process
|
8-Bromo Cyclic Adenosine Monophosphate
|
[8-Bromo Cyclic Adenosine Monophosphate results in increased positive regulation of steroid biosynthetic process] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone |
1: Mus musculus |
Leydig Cells
| Cell Line
|
|
1 |
50. |
17-alpha-Hydroxyprogesterone
|
negative regulation of oxidoreductase activity
|
Clotrimazole
| CYP17A1
|
[[Clotrimazole results in decreased activity of CYP17A1 protein] which results in increased negative regulation of oxidoreductase activity] which results in decreased chemical synthesis of 17-alpha-Hydroxyprogesterone |
|
Cell-Free System
|
|
1 |