| Title | Authors (identified) | Published In | Identifier(s) | Topic | Published Date | Match? |
|---|
| ANGPTL8 Blockade With a Monoclonal Antibody Promotes Triglyceride Clearance, Energy Expenditure, and Weight Loss in Mice | [1]Viktoria Gusarova, [2]Serena Banfi, [3]Corey A Alexa-Braun, [4]Lisa M Shihanian, [5]Ivory J Mintah, [6]Joseph S Lee, [7]Yurong Xin, [8]Qi Su, [9]Vishal Kamat, [10]Jonathan C. Cohen, [11]Helen Hobbs, [12]Brian Zambrowicz, [13]George D Yancopoulos, [14]Andrew J Murphy, [15]Jesper Gromada [Full author list] | Endocrinology [missing] | DOI: 10.1210/EN.2016-1894 [ORCID]
PubMed: 28204173 [ORCID]
| triglyceride [missing]; monoclonal antibody [missing] | 2017-05-01 | Jesper Gromada (Q89294485; 14 items)
|
| Activin A more prominently regulates muscle mass in primates than does GDF8 | [1]Esther Latres, [2]Jason Mastaitis, [3]Wen Fury, [4]Lawrence Miloscio, [5]Jesus Trejos, [6]Jeffrey Pangilinan, [7]Haruka Okamoto, [8]Katie Cavino, [9]Erqian Na, [10]Angelos Papatheodorou, [11]Tobias Willer, [12]Yu Bai, [13]Jee Hae Kim, [14]Ashique Rafique, [15]Stephen Jaspers, [16]Trevor Stitt, [17]Andrew J Murphy, [18]George D Yancopoulos, [19]Jesper Gromada [Full author list] | Nature Communications [missing] | DOI: 10.1038/NCOMMS15153 [ORCID]
PubMed: 28452368 [ORCID]
| | 2017-04-28 | Jesper Gromada (Q89294485; 14 items)
|
| ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance | [1]Jorge F Haller, [2]Ivory J Mintah, [3]Lisa M Shihanian, [4]Panayiotis Stevis, [5]David Buckler, [6]Corey A Alexa-Braun, [7]Sandra Kleiner, [8]Serena Banfi, [9]Jonathan C. Cohen, [10]Helen Hobbs, [11]George D Yancopoulos, [12]Andrew J Murphy, [13]Viktoria Gusarova, [14]Jesper Gromada [Full author list] | Journal of Lipid Research [missing] | DOI: 10.1194/JLR.M075689 [ORCID]
PubMed: 28413163 [ORCID]
| triglyceride [missing] | 2017-04-15 | Jesper Gromada (Q89294485; 14 items)
|
| Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition | [1]Haruka Okamoto, [2]Katie Cavino, [3]Erqian Na, [4]Elizabeth Krumm, [5]Steven Kim, [6]Panayiotis E Stevis, [7]Joyce Harp, [8]Andrew J Murphy, [9]George D Yancopoulos, [10]Jesper Gromada [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1620989114 [ORCID]
PubMed: 28143927 [ORCID]
| glucagon [missing] | 2017-01-31 | Jesper Gromada (Q89294485; 14 items)
|
| Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice | [1]Haruka Okamoto, [2]Katie Cavino, [3]Erqian Na, [4]Elizabeth Krumm, [5]Sun Kim, [6]Xiping Cheng, [7]Andrew J Murphy, [8]George D Yancopoulos, [9]Jesper Gromada [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1621069114 [ORCID]
PubMed: 28115707 [ORCID]
| insulin resistance [missing]; glucagon [missing] | 2017-01-23 | Jesper Gromada (Q89294485; 14 items)
|
| PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons | [1]Liheng Wang, [2]Lina Sui, [3]Sunil K Panigrahi, [4]Kana Meece, [5]Yurong Xin, [6]Jinrang Kim, [7]Jesper Gromada, [8]Claudia A Doege, [9]Sharon L Wardlaw, [10]Dieter Egli, [11]Rudolph Leibel [Full author list] | Stem Cell Reports [missing] | DOI: 10.1016/J.STEMCR.2016.12.021 [ORCID]
PubMed: 28132887 [ORCID]
| human embryonic stem cell [missing] | 2017-01-23 | Jesper Gromada (Q89294485; 14 items)
|
| RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes | [1]Yurong Xin, [2]Jinrang Kim, [3]Haruka Okamoto, [4]Min Ni, [5]Yi Wei, [6]Christina Adler, [7]Andrew J Murphy, [8]George D Yancopoulos, [9]Calvin Lin, [10]Jesper Gromada [Full author list] | Cell Metabolism [missing] | DOI: 10.1016/J.CMET.2016.08.018 [ORCID]
PubMed: 27667665 [ORCID]
| type 2 diabetes [missing]; single cell transcriptomics [missing] | 2016-09-09 | Jesper Gromada (Q89294485; 14 items)
|
| Single-Cell RNAseq Reveals That Pancreatic β-Cells From Very Old Male Mice Have a Young Gene Signature | [1]Yurong Xin, [2]Haruka Okamoto, [3]Jinrang Kim, [4]Min Ni, [5]Christina Adler, [6]Katie Cavino, [7]Erqian Na, [8]Andrew J Murphy, [9]George D Yancopoulos, [10]Calvin Lin, [11]Jesper Gromada [Full author list] | Endocrinology [missing] | DOI: 10.1210/EN.2016-1235 [ORCID]
PubMed: 27466694 [ORCID]
| RNA sequencing [missing]; single cell transcriptomics [missing] | 2016-07-28 | Jesper Gromada (Q89294485; 14 items)
|
| Mechano-signalling pathways in an experimental intensive critical illness myopathy model | [1]Rebeca Corpeno Kalamgi, [2]Heba Salah, [3]Stefano Gastaldello, [4]Vicente Martinez-Redondo, [5]Jorge L Ruas, [6]Wen Fury, [7]Yu Bai, [8]Jesper Gromada, [9]Roberta Sartori, [10]Denis C Guttridge, [11]Marco Sandri, [12]Lars Larsson [Full author list] | Journal of Physiology [missing] | DOI: 10.1113/JP271973 [ORCID]
PubMed: 26990577 [ORCID]
| | 2016-03-16 | |
| Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells | [1]Yurong Xin, [2]Jinrang Kim, [3]Min Ni, [4]Yi Wei, [5]Haruka Okamoto, [6]Joseph Lee, [7]Christina Adler, [8]Katie Cavino, [9]Andrew J Murphy, [10]George D Yancopoulos, [11]Hsin Chieh Lin, [12]Jesper Gromada [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1602306113 [ORCID]
PubMed: 26951663 [ORCID]
| single cell transcriptomics [missing] | 2016-03-07 | Jesper Gromada (Q89294485; 14 items)
|
| Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease | [1]Frederick E Dewey, [2]Viktoria Gusarova, [3]Colm O'Dushlaine, [4]Omri Gottesman, [5]Jesus Trejos, [6]Charleen Hunt, [7]Cristopher V Van Hout, [8]Lukas Habegger, [9]David Buckler, [10]Ka-Man V Lai, ..., [23]George D Yancopoulos, [24]Aris Baras, [25]Jesper Gromada, [26]Alan R. Shuldiner [Full author list] | The New England Journal of Medicine [missing] | DOI: 10.1056/NEJMOA1510926 [ORCID]
PubMed: 26933753 [ORCID]
| coronary artery disease [missing] | 2016-03-02 | Jesper Gromada (Q89294485; 14 items)
|
| Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice | [1]Esther Latres, [2]Jeffrey Pangilinan, [3]Lawrence Miloscio, [4]Roy Bauerlein, [5]Erqian Na, [6]Terra B Potocky, [7]Ying Huang, [8]Mark Eckersdorff, [9]Ashique Rafique, [10]Jason Mastaitis, [11]Calvin Lin, [12]Andrew J Murphy, [13]George D Yancopoulos, [14]Jesper Gromada, [15]Trevor Stitt [Full author list] | Skeletal Muscle [missing] | DOI: 10.1186/S13395-015-0060-8 [ORCID]
PubMed: 26457176 [ORCID]
| | 2015-10-09 | Jesper Gromada (Q89294485; 14 items)
|
| Loss of SFRP4 Alters Body Size, Food Intake, and Energy Expenditure in Diet-Induced Obese Male Mice | [1]Jason Mastaitis, [2]Mark Eckersdorff, [3]Soo Min, [4]Yurong Xin, [5]Katie Cavino, [6]Johnpaul Aglione, [7]Haruka Okamoto, [8]Erqian Na, [9]Trevor Stitt, [10]Melissa G Dominguez, [11]Jennifer P Schmahl, [12]Calvin Lin, [13]Nicholas W Gale, [14]David M Valenzuela, [15]Andrew J Murphy, [16]George D Yancopoulos, [17]Jesper Gromada [Full author list] | Endocrinology [missing] | DOI: 10.1210/EN.2015-1257 [ORCID]
PubMed: 26406932 [ORCID]
| obesity [missing] | 2015-09-25 | Jesper Gromada (Q89294485; 14 items)
|
| Hepatic ANGPTL3 regulates adipose tissue energy homeostasis | [1]Yan Wang, [2]Markey C McNutt, [3]Serena Banfi, [4]Michael G Levin, [5]William L Holland, [6]Viktoria Gusarova, [7]Jesper Gromada, [8]Jonathan C. Cohen, [9]Helen Hobbs [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1515374112 [ORCID]
PubMed: 26305978 [ORCID]
| | 2015-08-24 | |
| Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys | [1]Haruka Okamoto, [2]Jinrang Kim, [3]JohnPaul Aglione, [4]Joseph Lee, [5]Katie Cavino, [6]Erqian Na, [7]Ashique Rafique, [8]Jee Hae Kim, [9]Joyce Harp, [10]David M Valenzuela, [11]George D Yancopoulos, [12]Andrew J Murphy, [13]Jesper Gromada [Full author list] | Endocrinology [missing] | DOI: 10.1210/EN.2015-1011 [ORCID]
PubMed: 26020795 [ORCID]
| glucagon [missing] | 2015-05-28 | Jesper Gromada (Q89294485; 14 items)
|
| ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys | [1]Viktoria Gusarova, [2]Corey A Alexa, [3]Yan Wang, [4]Ashique Rafique, [5]Jee Hae Kim, [6]David Buckler, [7]Ivory J Mintah, [8]Lisa M Shihanian, [9]Jonathan C. Cohen, [10]Helen Hobbs, [11]Yurong Xin, [12]David M Valenzuela, [13]Andrew J Murphy, [14]George D Yancopoulos, [15]Jesper Gromada [Full author list] | Journal of Lipid Research [missing] | DOI: 10.1194/JLR.M054890 [ORCID]
PubMed: 25964512 [ORCID]
| lipid [missing]; monoclonal antibody [missing] | 2015-05-11 | Jesper Gromada (Q89294485; 14 items)
|
| Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion | [1]Yan Wang, [2]Viktoria Gusarova, [3]Serena Banfi, [4]Jesper Gromada, [5]Jonathan C. Cohen, [6]Helen Hobbs [Full author list] | Journal of Lipid Research [missing] | DOI: 10.1194/JLR.M054882 [ORCID]
PubMed: 25954050 [ORCID]
| triglyceride [missing] | 2015-05-07 | |
| GPR17 gene disruption does not alter food intake or glucose homeostasis in mice | [1]Jason Mastaitis, [2]Soo Min, [3]Ralf Elvert, [4]Aimo Kannt, [5]Yurong Xin, [6]Francisca Ochoa, [7]Nicholas W Gale, [8]David M Valenzuela, [9]Andrew J Murphy, [10]George D Yancopoulos, [11]Jesper Gromada [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1424968112 [ORCID]
PubMed: 25624481 [ORCID]
| | 2015-01-26 | Jesper Gromada (Q89294485; 14 items)
|
| ANGPTL8/betatrophin does not control pancreatic beta cell expansion | [1]Viktoria Gusarova, [2]Corey A Alexa, [3]Erqian Na, [4]Panayiotis E Stevis, [5]Yurong Xin, [6]Susan Bonner-Weir, [7]Jonathan C. Cohen, [8]Helen Hobbs, [9]Andrew J Murphy, [10]George D Yancopoulos, [11]Jesper Gromada [Full author list] | Cell [missing] | DOI: 10.1016/J.CELL.2014.09.027 [ORCID]
PubMed: 25417115 [ORCID]
| type B pancreatic cell proliferation [missing]; Angiopoietin like 8 [missing]; Angiopoietin-like 8 [missing] | 2014-10-01 | Jesper Gromada (Q89294485; 14 items)
|
| Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis | [1]Eriks Smagris, [2]Soumik BasuRay, [3]John Zhong Li, [4]Yongcheng Huang, [5]Ka-man V Lai, [6]Jesper Gromada, [7]Jonathan C. Cohen, [8]Helen Hobbs [Full author list] | Hepatology [missing] | DOI: 10.1002/HEP.27242 [ORCID]
PubMed: 24917523 [ORCID]
| steatosis [missing] | 2014-10-01 | |
| Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis | [1]Yan Wang, [2]Fabiana Quagliarini, [3]Viktoria Gusarova, [4]Jesper Gromada, [5]David M Valenzuela, [6]Jonathan C. Cohen, [7]Helen Hobbs [Full author list] | Proceedings of the National Academy of Sciences of the United States of America [missing] | DOI: 10.1073/PNAS.1315292110 [ORCID]
PubMed: 24043787 [ORCID]
| glucose [missing]; triglyceride [missing]; Angiopoietin-like 8 [missing] | 2013-09-16 | |