Temporary Disabled. :) please Go back AmiGO 2: Term Details for "GLI-SUFU complex" (GO:1990788) www.fgks.org » Address: [go: up one dir, main page] Include Form Remove Scripts Accept Cookies Show Images Show Referer Rotate13 Base64 Strip Meta Strip Title Session Cookies AmiGO 2 Home Search Annotations Ontology Genes and gene products Browse Tools & Resources Help Feedback About Search GLI-SUFU complex Notice Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page. Term Information Feedback Accession GO:1990788 Name GLI-SUFU complex Ontology cellular_component Synonyms None Alternate IDs None Definition A protein repressing GLI's transcription factor activity when SMO signaling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins. Source: PMID:24311597, GOC:bhm Comment An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay). History See term history for GO:1990788 at QuickGO Chem. react. None Subset None Related Link to all genes and gene products annotated to GLI-SUFU complex (excluding "regulates"). Link to all direct and indirect annotations to GLI-SUFU complex (excluding "regulates"). Link to all direct and indirect annotations download (limited to first 10,000) for GLI-SUFU complex (excluding "regulates"). Include "regulates" For more information, please see the ontology relation documentation. Annotations Graph Views Inferred Tree View Neighborhood Mappings Filter results Loading... pending... View this term in QuickGO. Additional external viewing options OLSVis (interactive) Additional internal viewing options Graphical view (PNG) Graphical view (SVG) GO:0008150 biological_process GO:0009987 cellular process GO:0008152 metabolic process GO:0009058 biosynthetic process GO:0044237 cellular metabolic process GO:0043170 macromolecule metabolic process GO:0006139 nucleobase-containing compound metabolic process GO:0044238 primary metabolic process GO:0050789 regulation of biological process GO:0050794 regulation of cellular process GO:0019222 regulation of metabolic process CARO:0030000 biological entity GO:0065007 biological regulation GO:0044249 cellular biosynthetic process GO:0009059 macromolecule biosynthetic process GO:0090304 nucleic acid metabolic process GO:0034654 nucleobase-containing compound biosynthetic process GO:0009889 regulation of biosynthetic process GO:0031323 regulation of cellular metabolic process GO:0080090 regulation of primary metabolic process CARO:0000000 anatomical entity GO:0007154 cell communication GO:0048519 negative regulation of biological process GO:0141187 nucleic acid biosynthetic process GO:0031326 regulation of cellular biosynthetic process GO:0060255 regulation of macromolecule metabolic process GO:0019219 regulation of nucleobase-containing compound metabolic process GO:0050896 response to stimulus GO:0016070 RNA metabolic process GO:0023052 signaling UBERON:0001062 anatomical entity UBERON:0000061 anatomical structure GO:0051716 cellular response to stimulus GO:0010467 gene expression CARO:0000006 material anatomical entity GO:0003674 molecular_function GO:0048523 negative regulation of cellular process GO:0010646 regulation of cell communication GO:0010556 regulation of macromolecule biosynthetic process GO:0048583 regulation of response to stimulus GO:0051252 regulation of RNA metabolic process GO:0023051 regulation of signaling GO:0032774 RNA biosynthetic process GO:0007165 signal transduction CL:0000000 cell GO:0007166 cell surface receptor signaling pathway GO:0110165 cellular anatomical entity CARO:0000003 connected anatomical structure GO:0006351 DNA-templated transcription UBERON:0000465 material anatomical entity GO:0010648 negative regulation of cell communication GO:0048585 negative regulation of response to stimulus GO:0023057 negative regulation of signaling GO:0006355 regulation of DNA-templated transcription GO:0010468 regulation of gene expression GO:2001141 regulation of RNA biosynthetic process GO:0009966 regulation of signal transduction GO:0007224 smoothened signaling pathway GO:0140110 transcription regulator activity GO:0005575 cellular_component GO:0003700 DNA-binding transcription factor activity GO:0005622 intracellular anatomical structure GO:0009968 negative regulation of signal transduction GO:0065009 regulation of molecular function GO:0008589 regulation of smoothened signaling pathway GO:0005737 cytoplasm GO:0045879 negative regulation of smoothened signaling pathway PR:000050567 protein-containing material entity GO:0051090 regulation of DNA-binding transcription factor activity GO:0005829 cytosol GO:1990787 negative regulation of hh target transcription factor activity GO:0032991 protein-containing complex GO:1990788 GLI-SUFU complex Parents of GLI-SUFU complex (GO:1990788) subject relation object GLI-SUFU complex BFO:0000050 cytosol (GO:0005829) GLI-SUFU complex is_a protein-containing complex (GO:0032991) GLI-SUFU complex RO:0002216 negative regulation of hh target transcription factor activity (GO:1990787) GLI-SUFU complex RO:0002162 cellular organisms (NCBITaxon:131567) This term has no children. 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