AmiGO 2: Term Details for "cytoplasm to vacuole targeting by the NVT pathway" (GO:0120113)

Accession: GO:0120113
Name: cytoplasm to vacuole targeting by the NVT pathway
Ontology: biological_process
Synonyms: protein localization by the Nbr1-mediated vacuolar targeting pathway
Alternate IDs: None
Definition: A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe. Source: PMID:26365378
Comment: None
History: See term history for GO:0120113 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to cytoplasm to vacuole targeting by the NVT pathway (excluding "regulates").; Link to all direct and indirect annotations to cytoplasm to vacuole targeting by the NVT pathway (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for cytoplasm to vacuole targeting by the NVT pathway (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
cytoplasm to vacuole targeting by the NVT pathway	BFO:0000051	vacuolar protein processing (GO:0006624)
cytoplasm to vacuole targeting by the NVT pathway	is_a	protein targeting to vacuole (GO:0006623)

subject	relation	object
NVT complex (GO:0061957)	RO:0002216	cytoplasm to vacuole targeting by the NVT pathway

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cytoplasm to vacuole targeting by the NVT pathway