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HAI2 highly ABA-induced PP2C protein 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837255, updated on 7-Sep-2023

Summary

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Gene symbol
HAI2
Gene description
highly ABA-induced PP2C protein 2
Primary source
Araport:AT1G07430
Locus tag
AT1G07430
See related
TAIR:AT1G07430
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AIP1; AKT1 interacting protein phosphatase 1; AtAIP1; F22G5.22; F22G5_22; highly ABA-induced PP2C gene 2; HON; HONSU (Korean for abnormal drowsiness)
Summary
Encodes a member of the group A protein phosphatase 2C (PP2C) family that is responsible for negatively regulating seed dormancy.
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Genomic context

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See HAI2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (2280746..2282828, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RAB GTPase homolog A2B Neighboring gene sterol 4-alpha-methyl-oxidase 2-1 Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HONSU, a protein phosphatase 2C, regulates seed dormancy by inhibiting ABA signaling in Arabidopsis. Kim W, et al. Plant Cell Physiol, 2013 Apr. PMID 23378449
  2. Functional roles of the protein phosphatase 2C, AtAIP1, in abscisic acid signaling and sugar tolerance in Arabidopsis. Lim CW, et al. Plant Sci, 2012 May. PMID 22404835
  3. Mechanistic analysis of AKT1 regulation by the CBL-CIPK-PP2CA interactions. Lan WZ, et al. Mol Plant, 2011 May. PMID 21596690
  4. Unique drought resistance functions of the highly ABA-induced clade A protein phosphatase 2Cs. Bhaskara GB, et al. Plant Physiol, 2012 Sep. PMID 22829320, Free PMC Article
  5. The unique mode of action of a divergent member of the ABA-receptor protein family in ABA and stress signaling. Zhao Y, et al. Cell Res, 2013 Dec. PMID 24189045, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_100617.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of seed dormancy process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of gibberellic acid mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of seed germination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within release of seed from dormancy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
highly ABA-induced PP2C protein 2
NP_172223.1
  • highly ABA-induced PP2C gene 2 (HAI2); FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: protein amino acid dephosphorylation; LOCATED IN: protein serine/threonine phosphatase complex; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C, manganese/magnesium aspartate binding site (InterPro:IPR000222), Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: highly ABA-induced PP2C gene 3 (TAIR:AT2G29380.1); Has 6753 Blast hits to 6737 proteins in 407 species: Archae - 6; Bacteria - 193; Metazoa - 1700; Fungi - 794; Plants - 2782; Viruses - 7; Other Eukaryotes - 1271 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    2280746..2282828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100617.3 → NP_172223.1  highly ABA-induced PP2C protein 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172223.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LFK5, Q9LNW3
    UniProtKB/TrEMBL
    A0A178W3W3, A0A5S9T3B3
    Conserved Domains (1) summary
    smart00332
    Location:116 → 431
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LNW3.1

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