Publication Name	World Journal of Hepatology
Manuscript ID	91369
Country	Greece

Received	2023-12-27 15:21
Peer-Review Started	2023-12-27 15:21
To Make the First Decision
Return for Revision	2024-02-23 05:53
Revised	2024-03-02 17:28
Second Decision	2024-04-17 02:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-17 07:17
Articles in Press	2024-04-17 07:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-11 02:51
Publish the Manuscript Online	2024-05-22 11:33

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Liver disease in patients with transfusion-dependent β-thalassemia: The emerging role of metabolism dysfunction-associated steatotic liver disease
Manuscript Source	Invited Manuscript
All Author List	Nikolaos Fragkou, Efthimia Vlachaki, Ioannis Goulis and Emmanouil Sinakos
Funding Agency and Grant Number
Corresponding Author	Emmanouil Sinakos, MD, PhD, Assistant Professor, 4th Department of Internal Medicine, Hippokratio Hospital, Aristotle University of Thessaloniki, Konstantinoupoleos Str. 49, Thessaloniki 54642, Greece. em_sinakos@yahoo.com
Key Words	Metabolism dysfunction-associated steatotic liver disease; Transfusion-dependent thalassemia; Metabolic syndrome; Hepatic steatosis; Non-invasive markers; Liver fibrosis
Core Tip	Transfusion-dependent β-Thalassemia (TDBT) is one of the most frequent congenital diseases. Advances in the care of patients with TDBT over the past two decades have managed to significantly increase their life expectancy, making them more vulnerable to the onset of diseases related to the metabolic syndrome. Recent data from a relatively small study have highlighted the significance of the presence of hepatic steatosis in these patients. We herein discuss the available data concerning the presence of hepatic steatosis in this population, and the potential implications that these findings could have in the management of patients with TDBT, should these results be confirmed in larger cohorts.
Publish Date	2024-05-22 11:33
Citation	<p>Fragkou N, Vlachaki E, Goulis I, Sinakos E. Liver disease in patients with transfusion-dependent β-thalassemia: The emerging role of metabolism dysfunction-associated steatotic liver disease. <i>World J Hepatol</i> 2024; 16(5): 671-677</p>
URL	https://www.wjgnet.com/1948-5182/full/v16/i5/671.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i5.671

Full Article (PDF)	WJH-16-671-with-cover.pdf
Manuscript File	91369_Auto_Edited-YJP.docx
Answering Reviewers	91369-Answering reviewers.pdf
Audio Core Tip	91369-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	91369-Conflict-of-interest statement.pdf
Copyright License Agreement	91369-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	91369-Language certificate.pdf
Peer-review Report	91369-Peer-review(s).pdf
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Scientific Editor Work List	91369-Scientific editor work list.pdf
CrossCheck Report	91369-CrossCheck report.pdf
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