The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 03 July 2024, EMDB contains 36718 entries (latest entries, trends).
EMDB News
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06 January 2024: We are delighted to share that EMDB has officially been elevated to a Core Data Resource by ELIXIR, recognising it as a European data resource of fundamental importance to the wider life-science community and the long-term preservation of biological data.
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22 November 2023: We are happy to share the most recent version of the EMDB Nucleic Acids Research paper. The paper describes recent developments and future plans of the EMDB in the context of the worldwide Protein Data Bank. Check it out now! https://doi.org/10.1093/nar/gkad1019
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(Show all)In situ structure average of GroEL14-GroES7 complexes with wide GroEL7 trans ring conformation in Escherichia coli cytosol obtained by cryo electron tomography
CryoEM structure of a (GroEL)14-(GroES)14 complex with encapsulated ordered MetK substrate in one chamber and no or disordered MetK substrate in the other chamber in the presence of ADP-BeFx
Endosomal membrane tethering complex CORVET, Vps8 beta propeller local refinement map
In situ structure average of GroEL7-GroES7 chamber with encapsulated, ordered substrate in Escherichia coli cytosol obtained by cryo electron tomography
In situ structure average of GroEL14-GroES7 complexes with narrow GroEL7 trans ring conformation in Escherichia coli cytosol obtained by cryo electron tomography
Endosomal membrane tethering complex CORVET, SNARE binding module local refinement map
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '3 up' RBD conformation
CryoEM structure of a GroEL7-GroES7 cage with encapsulated disordered substrate MetK in the presence of ADP-BeFx
CryoEM structure of a GroEL14-GroES7 complex in presence of ADP-BeFx with wide GroEL7 trans ring conformation
CryoEM structure of a GroEL7-GroES7 cage with encapsulated ordered substrate MetK in the presence of ADP-BeFx
Conformer 5 of the (GroEL)14(GroES)14 complex with two encapsulated, near-native and ordered MetK substrates in the presence of ADP-BeFx
Cryo-ET subtomogram of 70S ribosomes in Escherichia coli cells overexpressing GroEL
CryoEM structure of a GroEL14-GroES7 cage with encapsulated disordered substrate MetK in the presence of ADP-BeFx
CryoEM structure of a C7-symmetrical GroEL7-GroES7 cage in presence of ADP-BeFx
Conformer 7 of the (GroEL)14(GroES)14 complex with two encapsulated, near-native and ordered MetK substrates in the presence of ADP-BeFx
Conformer 4 of the (GroEL)14(GroES)14 complex with two encapsulated, near-native and ordered MetK substrates in the presence of ADP-BeFx
CryoEM structure of a GroEL14-GroES7 cage with encapsulated ordered substrate MetK in the presence of ADP-BeFx
Cryo-EM structure of a C7-symmetrical GroEL14-GroES7 complex in presence of ADP-BeFx
Structure average of GroEL14 complexes found in the cytosol of Escherichia coli overexpressing GroEL obtained by cryo electron tomography
CryoEM structure of DHS-eIF5A complex structure from Trichomonas vaginalis
Cryo-EM structure of a D7-symmetrical GroEL14-GroES14 complex in presence of ADP-BeFx
Symmetry-averaged GroEL7-GroES7 chamber with encapsulated ordered substrate MetK obtained by in vitro cryo electron tomography
Endosomal membrane tethering complex CORVET, Vps18 beta propeller local refinement map
Conformer 6 of the (GroEL)14(GroES)14 complex with two encapsulated, near-native and ordered MetK substrates in the presence of ADP-BeFx
Endosomal membrane tethering complex CORVET, core local refinement map
In situ structure average of GroEL14-GroES14 complexes in Escherichia coli cytosol obtained by cryo electron tomography
CryoEM structure of a GroEL14-GroES14 cage with two encapsulated disordered MetK substrates in the presence of ADP-BeFx
Endosomal membrane tethering complex CORVET, Vps8-Vps11 local refinement map
CryoEM structure of a GroEL14-GroES7 complex in presence of ADP-BeFx with narrow GroEL7 trans ring conformation
Symmetry-averaged GroEL7-GroES7 chamber with encapsulated disordered substrate MetK obtained by in vitro cryo electron tomography
Conformer 1 of the (GroEL)14(GroES)14 complex with two encapsulated, ordered and near-native MetK substrate molecules in the presence of ADP-BeFx
Cryo-ET subtomogram of 70S ribosomes in Escherichia coli cells at 37 and 46 degrees centigrade and in Escherichia coli cells overexpressing GroELS and MetK
Outward-open structure of human dopamine transporter bound to cocaine
Conformer 3 of the (GroEL)14(GroES)14 complex with two encapsulated, near-native and ordered MetK substrates in the presence of ADP-BeFx
Conformer 2 of the (GroEL)14(GroES)14 complex with two encapsulated, near-native and ordered MetK substrates in the presence of ADP-BeFx
In situ structure average of GroEL7-GroES7 chamber with no or disordered substrate in Escherichia coli cytosol obtained by cryo electron tomography
6-channel super-structure of the Mechanosensitive Ion Channel of Small Conductance 2 from Nematocida displodere
Atomic model of the mammalian mouse Mediator complex with CKM module
HIV-1 JR-FL NFL.664 soluble trimer in complex with polyclonal Fab from rabbit U5756
Focused map of the cytoplasmic domains of rat TRPM5, conformation trace-3
Closed state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis
HIV-1 1086c NFL.664 soluble trimer in complex with polyclonal Fab from rabbit U5919
HIV-1 JR-FL NFL.664 soluble trimer in complex with polyclonal Fab from rabbit U5902
Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-2
WT CRISPR-Cas12a with a 20bp R-loop and nontarget strand in the RuvC active site.
Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-1
Focused map of the cytoplasmic domains of rat TRPM5, conformation high-2
WT CRISPR-Cas12a post nontarget strand-cleavage with the the RuvC active site exposed.
Escherichia coli RNA polymerase unwinding intermediate (I1b) at the lambda PR promoter
Focused map of the cytoplasmic domains of rat TRPM5, conformation high-3
Escherichia coli RNA polymerase closed complex intermediate at the lambda PR promoter
Focused map of the cytoplasmic domains of rat TRPM5, conformation trace-1
Open state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis
Escherichia coli RNA polymerase unwinding intermediate (I1d) at the lambda PR promoter
Cryo-EM structure of the rat TRPM5 channel in trace calcium, trace-3
Escherichia coli RNA polymerase unwinding intermediate (I1c) at the lambda PR promoter
CryoEM structure of Cryptococcus neoformans H99 Acetyl-CoA Synthetase in complex with adenosine-5'-ethylphosphate
Structure of the Measles virus Fusion protein in the post-fusion conformation
Escherichia coli RNA polymerase unwinding intermediate (I1a) at the lambda PR promoter
Structure of the Measles virus Fusion protein in the pre-fusion conformation
Open human HCN1 F186C S264C bound to cAMP, reconstituted in LMNG + SPL
Focused map of the cytoplasmic domains of rat TRPM5, conformation trace-2
Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, V1
CryoEM structure of Apo Cryptococcus neoformans H99 Acetyl-CoA Synthetase
Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-3
Focused map of the cytoplasmic domains of rat TRPM5, conformation high-1
Aldolase at 100 keV on the Alpine detector with a side-entry cryoholder
Apoferritin at 100 keV on Alpine detector with a side-entry cryoholder
WT CRISPR-Cas12a with a 16bp R-loop and nontarget strand in the RuvC active site.
HIV-1 1086c NFL.664 soluble trimer in complex with polyclonal Fab from rabbit U5403
Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-1
Structure of the Measles virus Fusion protein in the pre-fusion conformation with bound [FIP-HRC]2-PEG11
Focused map of the cytoplasmic domains of rat TRPM5, conformation high-4
Cryo-EM structure of nucleosome containing Arabidopsis thaliana H2A.W
Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P), RBD-closed state
Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P), RBD-closed state
Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2
Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state with MCoA
Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant escitalopram in an inward-open state at resolution of 2.85 angstrom.
SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein)
Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 and S309 Fab
SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein)
Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2
Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state
alpha-Hemolysin(G122S/K147R)-SpyTag/SpyCatcher head to head 14-mer
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2
Cryo-EM structure of SARS-CoV-2 Omicron JN.1 RBD in complex with human ACE2 (local refinement from the spike protein)
alpha-Hemolysin(G122S/K147R/K237C)-SpyTag/SpyCatcher head to head 14-mer
Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state with MCoA
Cryo-EM structure of nucleosome containing Arabidopsis thaliana histones
The open structure of the mechanosensitive channel MSL10 in Arabidopsis thaliana
Cryo-EM structure of the Type II secretion system protein from Acidithiobacillus caldus
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2
Cryo-EM structure of apo-state huamn angiotensin-converting enzyme 2 (ACE2)
BA.2.86-T356K Spike Trimer in complex with heparan sulfate (Local refinement)