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Introduction to Biological and Small Molecule Drug Research and Development: Chapter 12. Hormone replacement therapy

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Menopause affects the quality of life for women, sometimes severely. The symptoms can be addressed by treatment with steroids, namely, an oestrogen alone or an oestrogen with a progestin. The treatment is called hormone replacement therapy (HRT). However, for years, HRT has been associated with side effects, for instance, an increased risk of breast or endometrial cancer and stroke. The potentially positive effect of reducing some forms of heart disease is still a matter of debate, while the HRT-related decrease in bone fracture/osteoporosis is more certain. The rise, fall and current status of HRT is summarized in this chapter.

26 pages, Kindle Edition

Published May 7, 2013

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