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2020, Pediatric Hematology Oncology Journal
Medicinski pregled
Simplified dermatoscopic criteria for diagnosing benign and dysplastic melanocytic lesions and melanoma of the skin: indications for surgical removalJournal of Clinical and Diagnostic Research
Pigmented Pre-malignant and Malignant Lesions of Skin with Special Reference to Atypical PresentationsBackground: Cutaneous melanocytic proliferations are diverse both morphologically as well as in their behavioural patterns. Both dermatologists and pathologists regularly encounter diagnostic dilemmas while interpreting such lesions. Aim: To study all cutaneous premalignant and malignant lesions with respect to their clinical features and histopathological findings. Materials and Methods: A retrospective study was done in the Department of Pathology over a period of 10 years (2004-14) on all the clinically pigmented lesions that were biopsied or excised. Out of these only premalignant and malignant melanocytic lesions were analysed with respect to their important clinical and histologic features. Immunohistochemistry was carried out using HMB-45 and S-100 where indicated. Results: A total of 338 skin cancers were reported, out of these 27, 7.9% were cutaneous malignant melanoma. Premalignant lesions were 33. The mean age for premalignant lesions and melanomas was 43 years and 50.7 y...
Acta dermatovenerologica Croatica : ADC
Melanoma--clinical, dermatoscopical, and histopathological morphological characteristics2014 •
Melanoma is one of the most malignant skin tumors with constantly rising incidence worldwide, especially in fair-skinned populations. Melanoma is usually diagnosed at the average age 50, but, nowadays is also diagnosed more frequently in younger adults, and very rarely in childhood. There is no unique or specific clinical presentation of a melanoma. The clinical presentation of melanomas varies depending on the anatomic localization and the type of growth, i.e., the histopathological type of the cancer. There are four major histopathological types of melanoma--superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma, and acral lentiginous melanoma. Although dermatoscopy is a very useful tool in early melanoma detection, dermatoscopical features of melanomas are also variable. Therefore, experience and education in dermatoscopy is crucial in the evaluation of skin tumors. Differential diagnosis of melanomas includes a wide range of benign and malignant skin lesions,...
IP Innovative Publication Pvt. Ltd.
A variety of skin tumors arise from the epidermis, epidermal appendages, dermis and subcutis. Many a time clinical diagnosis becomes difficult, when histopathological examination (HPE) aids in arriving at the correct diagnosisAbstract Objectives: To study the clinical spectrum and histopathological features of suspected skin tumors, analyze the concurrence rate between the clinical and histopathological diagnoses and highlight the role of histopathology in diagnosing skin tumors. Materials and Method: Suspected skin tumours are as a routine biopsied for histopathological examination. A retrospective study was conducted from the documented data available over a period of 8 months in the department of dermato-venereoleprology at a tertiary care centre. A total of 65 patients with suspected skin tumors had undergone skin biopsy for histopathological examination after clinical evaluation. Sections had been stained with hematoxylin and eosin for basic study and immunohistochemistry in difficult cases. Results: Out of 65 clinically suspected cases, only 59(90.7%) were skin tumors; among them, clinical diagnosis correlated with histopathological features in only 35(53.8%) patients. In 19(29.2%) cases, HPE was needed for accurate diagnosis and 5(7.69%) patients needed Immunohistochemistry in addition. The most common age group was 18-35 years. The male female ratio was 1.2 1. The majority of lesions were located on the head and neck (34 cases; 57%) and the least on the vulva (1 case; 1.6%). Benign tumors were mostly soft tissue and adnexal tumors, the most common being neurofibroma; malignant lesions included basal cell carcinoma, squamous cell carcinoma and mycosis fungoides. Conclusion: Histopathological examination is crucial to arrive at the correct diagnosis of clinically suspected skin tumors; this study emphasizes its pivotal role in the accurate diagnosis of skin tumors.
Journal of the American Academy of Dermatology
Clinical and dermoscopic characterization of pediatric and childhood melanomas. Multicenter study of 52 cases2017 •
Knowledge regarding the morphologic spectrum of pediatric melanoma (PM) is sparse and this may in part contribute to delay in detection and thicker tumors. to analyze the clinical-dermoscopic characteristics of PM. retrospective study of 52 melanomas diagnosed before age of 20. Based on clinical, dermoscopic and histopathological characteristics, PM can be classified as Spitzoid and Non-Spitzoid Non-Spitzoid (37, 72.3%) melanomas presented at a mean age of 16.3 (8-20) and were associated with a high-risk phenotype and a preexisting nevus (62.2%). Spitzoid melanomas (15, 27.7%) were diagnosed at a mean age of 12.5 (2-19) and were mostly de novo lesions (73.3%) located on the limbs (73.3%). While less than 25% of PM fulfilled the modified clinical ABCD criteria, 40% of spitzoid melanomas did. Non-Spitzoid tended to be multicomponent (58.3%) or nevus-like patterns (25%). Dermoscopic melanoma criteria were found in all cases. Spitzoid melanomas revealed atypical vascular patterns with s...
American Journal of Medical Case Reports
Atypical Presentation of Malignant Melanoma in a 16 Months Old Child2015 •
https://www.ijhsr.org/IJHSR_Vol.9_Issue.12_Dec2019/IJHSR_Abstract.02.html
Morphological Gamut of Various Neoplastic Lesions of SkinSkin cancer constitutes a significant proportion of all neoplasms, constituting less than 1% of all diagnosed cancers in India. The incidence of skin cancer is gradually increasing over last few decades. Neoplasms of skin arise from epidermis, adnexal structures, dermis and neuroendocrine cells. (1) Histological examination gives more information to the clinician thereby facilitating better treatment modalities. (2) They pose a diagnostic challenge and range from a simple benign tumours causing cosmetic concern to premalignant and aggressive malignant tumours. (3) Hence till date, histopathology remains the gold standard in diagnosing any neoplastic lesions of skin. Aim was to study the various histopathological types of skin tumours. This was a retrospective study done over a three year period. Out of all the skin biopsies received, only neoplastic conditions were selected for the study. A total of 121 tumours were considered for the study. Most common age group of presentation was between 60-69 years (21.4 %); youngest being 4years and oldest was 86 years. Slight Male preponderance (51.5%) was observed in the study. Out of 121 cases, 73 were benign neoplasms (60.3%) and malignant neoplasms were seen in 48 cases (39.6%). Among all the skin neoplasms, nonmelanocytotic tumours were frequently seen (78.5%). Out of 121 cases, 118 were of primary skin tumours and only 3 cases were of metastatic skin deposits. The present study highlights that knowledge of histopathologic patterns helps in early diagnosis, prognosis and also to plan an effective management modality.
Journal of the European Academy of Dermatology and Venereology : JEADV
Clinical, histopathological, dermatoscopic and digital microscopic features of dermatofibroma: a retrospective analysis of 200 lesions2015 •
Dermatology literature lacks a study investigating both histopathological and dermatoscopic features of dermatofibroma. To analyse histopathological, dermatoscopic and digital microscopic features of dermatofibromas. Two hundred dermatofibromas and 190 patients were included and retrospectively evaluated. Nine histopathological and ten dermatoscopic patterns were used to classify the lesions. We identified four different types of dermatofibroma in digital microscopy. The mean age of the patients was 42.18 ± 13.72 years. Dermatofibroma was more common in females (67%) and the male to female ratio was 1 : 1.97. The most common location was leg (41%). The most frequent histopathological variant was fibrocollagenous type (49%). Grenz zone was the most common histopathological finding (89%). The most frequent digital microscopic type was type 1 (63%). We found that palisading variant displayed only pattern 6 in dermatoscopy and cellular variant showed type 3 significantly in digital micr...
British Journal of Dermatology
Dermoscopy is useful for the recognition of benign-malignant compound tumours2005 •
2015 •
Neurochemistry International
Changes in neurohypophysial cholecystokinin content during oestrous cycle in the rat1984 •
Strengthen a Marriage and Avoid a Divorce
How to Stop a Divorce and Save Your Marriage: Divorce Spells That Really Work - Spells for Divorce or to Prevent a Divorce (WhatsApp: +27836633417)2024 •
Journal of Sports and Motor Development and Learning
The Effects of Selected Spark Exercises on Balance and Coordination in Autistic Children: A Quasi-Experimental StudyIEEE Consumer Electronics Magazine
Collaborative Efforts Fuel the Greece Chapter [Society News]2015 •
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Effect of Proton Pump Inhibitors in Bronchiectatic Patients with Gastroesophageal Reflux Disease2016 •
Current Pharmaceutical Biotechnology
Isolation of Achyrobichalcone from Achyrocline satureioides by High- Speed Countercurrent Chromatography2015 •
2018 •
European Journal of Surgical Oncology
Does serum bilirubin at presentation have an impact on survival in patients with hilar cholangiocarcinoma (HCCA)?2018 •