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2018, Parkinsonism & Related Disorders
Movement Disorders
The most cited works in Parkinson's disease2010 •
The number of citations a work has received is a measure of its impact. We identified the top cited works in Parkinson's disease. A Web of Science search was performed for articles including the keyword "Parkinson*" in the title (the asterisk was included in the search string as a wild card character). Articles with more than 400 citations, the threshold to be considered a "citation classic," were identified and analyzed. The 107 articles identified appeared in 33 different journals, with clinical articles primarily appearing in the New England Journal of Medicine and Lancet, and scientific articles primarily in Nature, Science, and the Proceedings of the National Academy of Sciences. There were 52 laboratory studies, 38 clinical studies, 12 review articles, and 5 classifications of disease. The clinical studies included evaluation of medical and surgical therapies, and the laboratory studies included gene discovery, molecular biology, and cellular biology, as well as animal models and neuropathological studies. High impact topics included deep brain stimulation, levodopa therapy and related adverse effects, MPTP-based animal studies, discovery and evaluation of genetic mutations, and pathogenesis related to oxidative degeneration. More than half of the articles identified in this study have been published in the past 20 years. Prior to 1990, highly cited articles in Parkinson's disease tended to be those that evaluated medical therapies and defined the clinical and neuropathological characteristics of the disease. Since 1990, a high proportion of the citation classics address the genetic characterization of and surgical treatments for the disease suggesting that these are the most significant recent developments and main drivers of impact in this field.
The Lancet. Neurology
Global, regional, and national burden of Parkinson's disease, 1990-2016: a systematic analysis for the Global Burden of Disease Study 20162018 •
Neurological disorders are now the leading source of disability globally, and ageing is increasing the burden of neurodegenerative disorders, including Parkinson's disease. We aimed to determine the global burden of Parkinson's disease between 1990 and 2016 to identify trends and to enable appropriate public health, medical, and scientific responses. Through a systematic analysis of epidemiological studies, we estimated global, regional, and country-specific prevalence and years of life lived with disability for Parkinson's disease from 1990 to 2016. We estimated the proportion of mild, moderate, and severe Parkinson's disease on the basis of studies that used the Hoehn and Yahr scale and assigned disability weights to each level. We jointly modelled prevalence and excess mortality risk in a natural history model to derive estimates of deaths due to Parkinson's disease. Death counts were multiplied by values from the Global Burden of Disease study's standard ...
Neuroscience Letters
Bibliometric analysis on global Parkinson's disease research trends during 1991–20062008 •
2011 •
Background: A number of epidemiologic studies of Parkinson 's disease (PD) have been conducted worldwide over the years. Although every study reported the rise in prevalence and incidence rate of PD with the increasing age, the overall estimates were different across countries. The variation in reported data may partly be contributed by case ascertainment, case finding method, data collection, and most importantly different population structures. Objective: Systematically review prevalence and incidence of PD and find the causes of variation in the results. Material and method: A literature search was conducted on Medline and EMBASE for studies worldwide investigating the prevalence and incidence of PD and included all adults, English and publication between 1965 and January 2010. The primary search of both databases yielded 5,330 results. After screening topics and abstracts, 168 relevant abstracts were tagged and saved for more thorough perusal. Ultimately, 40 papers were selected for review after applying the pre-specified inclusion criteria Results: The worldwide prevalence of PD varies widely. One reason for the variation in prevalence estimates could be due to the differences in survival across countries. The use of epidemiological studies using medical records could be another reason for the variation in disease frequency. Conclusion: PD is common in the elderly. A number of descriptive epidemiologic studies have been conducted worldwide. Comparing the incidence and prevalence of Parkinson's disease is difficult.
Parkinsonism & Related Disorders
Unmet needs in Parkinson's disease: New horizons in a changing landscape2016 •
American Journal of Biomedical Science & Research
Update on Parkinson's DiseaseAbstract Parkinson’s disease (PD) is a progressive nervous system disorder that affect movement and present other symptoms, that can be different for everyone and the exact cause of this damage is still unknown. Parkinson’s disease can’t be cured, medications and surgeries might significantly improve their symptoms, these must be prescribed by the neurologist, but it is important to understand how the medication works, what do we expect from them and what other options are available today. In this review the goal is introduce and explain to PD patients and their caregivers the PD: symptoms, stages, treatments, causes and types.Keywords: Parkinson’s disease; Tremors; Movement disorders; Postural instability; Levodopa; Parkinsonism; Idiopathic Parkinson’s; Atypical parkinsonismAbbrevations: PD: Parkinson’s Disease; CNS: Central Nervous System; MRI: Magnetic Resonance Imaging; STN: Subthalamic Nucleus; GPI: Globus Pallidus Internal; DBS: Deep Brain Stimulation; IPG: Implanted Pulse Generator; UPDRS: Unified Parkinson’s Disease Rating Scale; L-DOPA: Levodopa; LRRK2: Leucine-Rich Repeat Kinase 2; PARK7: Parkinsonism Associated Deglycase; PRKN: Parkin Rbr E3 Ubiquitin Protein Ligase; TMS: Transcranial Magnetic Stimulation; THC: Tetrahydrocannabinol; CBD: Cannabidiol; TCE: Trichloroethylene; CSE: Chronic Solvent Encephalopathy; MSA: Multiple System Atrophy; PSP: Progressive Supranuclear Palsy; CBS: Corticobasal Syndrome; DLB: Dementia with Lewy Bodies; VP: Vascular Parkinsonism; PBA: Pseudobulbar Affect.
Alzheimers Disease & Dementia
Parkinson's Disease: Old Concepts and New ChallengesParkinsonism & Related Disorders
Clinically meaningful parameters of progression and long-term outcome of Parkinson disease: An international consensus statement2015 •
The International journal of neuroscience
Awareness and current knowledge of Parkinson disease: A Neurodegenerative disorder2018 •
Parkinson's disease is the second common progressive neurodegenerative disease, distressing older men and is prevalent Worldwide. This paper is aimed to review the epidemiology, etiology, pathogenesis, clinical manifestation, diagnosis and management of Parkinson disease. A google search was performed to recognize studies that review the characteristics of Parkinson disease. Search terms included " Parkinson's disease", " epidemiology", " etiology", " pathogenesis", " clinical manifestations", " diagnosis" and " management of Parkinson disease". Parkinson's disease is linked to factors such as environmental chemicals, aging, family history and pesticide exposure such as the use of synthetic heroin. Parkinson's disease is characterized clinically by tremors at rest, postural instability, expressionless countenance, lead pipe rigidity and less commonly cognitive impairment. After 60 years of age, Par...
Dong Thap University Journal of Science
Ba thuật toán giải phương trình, bất phương trình, hệ phương trình vô tỷ bằng cách thêm bớt biểu thức liên hợp2016 •
Phương trình, bất phương trình, hệ phương trình chứa căn thức là dạng toán phân hóa học sinh trong đề thi tuyển sinh Đại học. Thêm bớt biểu thức liên hợp là cách giải đặc trưng của dạng toán này. Bài báo đưa ra 3 thuật toán giải phương trình, bất phương trình, hệ phương trình vô tỷ bằng cách thêm bớt biểu thức liên hợp:“trị số Bezout”, “cát tuyến gốc”, “đồng dạng tử thức”.
AN ASSESMENT OF THE FACTORS AFFECTING THE GROWTH OF SAVINGS AND CREDIT COOPERATIVES IN MALAWI
AN ASSESMENT OF THE FACTORS AFFECTING THE GROWTH OF SAVINGS AND CREDIT COOPERATIVES IN MALAWI2014 •
Интеграция образования
Обучение говорению на иностранном языке с наставником-ровесником2018 •
International journal of pharmaceutical sciences review and research
An Overview on Drug-Food Interactions2022 •
2028 •
Photochemical & Photobiological Sciences
A dendritic fullerene?porphyrin dyad2006 •
Journal of Pediatric Endocrinology and Metabolism
Effects of Phenylalanine, Histidine, and Leucine on Basal and GHRH-stimulated GH Secretion and on PRL, Insulin, and Glucose Levels in Short Children. Comparison with the Effects of Arginine1996 •
Economic Paper
Climate Change and Small Island Developing States Lino Briguglio, Kanayathu Koshy, Leonard Nurse and Poh Poh Wong2008 •
Dendrochronologia
A comparison of some simple methods used to detect unstable temperature responses in tree-ring chronologies2018 •
RePEc: Research Papers in Economics
How to improve public sector finances in Honduras1989 •
JOURNAL OF COMMUNITY SERVICES PUBLIC AFFAIRS
Mempersiapkan Masyarakat Menghadapi Masa New Normal Saat Pandemi Covid-19