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2010, Journal of Agricultural Science and Technology
Probiotic products highly affect the health of consumers by reducing the risk of heart attacks and improving the desirable microflora in the intestinal tract. In this study the effect of yogurt (500g/d for 3 wk) enriched with either Bifidobacterium bifidum or Lactobacillus acidophilus on the level of cholesterol, Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL) of serum and as well on the intestinal microflora were investigated in 24 healthy volunteers. Statistical analysis indicated that lower levels of cholesterol and HDL were found after consumption of either one of bio-yogurts as compared to the control states ( P<0.05), whereas changes of LDL were not significant. Also, in comparison with control periods the results of microbial counts indicated that the number of fecal coliforms excreted during the consumption of either one of the yogurt types were not noticeable, while the number of Bifidobacterium bifidum and Lactobacillus acidophilus increased significant...
2016 •
The aim of the present study was to evaluate and confirm in vivo the cholesterol lowering effect of three commercialized yogurts sold in Buea, a town located in the South West Region of Cameroon. These yogurts are normally known to contain Lactobacillus plantarum and Streptococcus thermophilus bacteria. Following diet induced hyperlipidemia, animal model (wistar albino rats) was used to confirm the persistence of their probiotic cholesterol lowering effect after processing. 42 rats were divided into 7 groups: the positive control group (received hyperlipidemia diet (cholesterol /lard rich diet) + oral gavage of deionized water), the negative control group (fed with basal diet +oral gavage of deionized water), three test groups (fed with hyperlipidemia diet and 3 different types of commercialized yogurt administered orally by gavage respectively), ferment free group (received basal diet + oral administration of yogurt constituents free of ferments (culture)) and hyperlipidemia fermen...
The aim of the present study was to evaluate and confirm in vivo the cholesterol lowering effect of three commercialized yogurts sold in Buea, a town located in the South West Region of Cameroon. These yogurts are normally known to contain Lactobacillus plantarum and Streptococcus thermophilus bacteria. Following diet induced hyperlipidemia, animal model (wistar albino rats) was used to confirm the persistence of their probiotic cholesterol lowering effect after processing. 42 rats were divided into 7 groups: the positive control group (received hyperlipidemia diet (cholesterol /lard rich diet) + oral gavage of deionized water), the negative control group (fed with basal diet +oral gavage of deionized water), three test groups (fed with hyperlipidemia diet and 3 different types of commercialized yogurt administered orally by gavage respectively), ferment free group (received basal diet + oral administration of yogurt constituents free of ferments (culture)) and hyperlipidemia ferment free group (received hyperlipidemia diet + oral yogurt constituents free of ferments). The oral gavage was daily and the dose volume administered was 1.0 ml/kg body weight. The rats were acclimatized for one week followed by the experimental phase properfor 4 weeks. Daily food consumed and daily weight gains were recorded. At the end of the fourth week, rats were dissected and blood collected for biochemical analysis (total cholesterol, triglycerides, LDL-cholesterol, HDL-cholesterol, VLDL-cholesterol, albumin and transaminases activities (ASAT and ALAT)). Organs of the rats (heart, liver, spleen and kidney) were also removed and weighed. Rat growth response revealed no significant change in weight of rats as well as in weights of different organs among test groups meanwhile the weight of these organs and the weight gained by hyperlipidemic group were relatively high compared to test and negative control groups. A slight elevation of ASAT and ALT activities was observed only in Hyperlipidemia rats while the test group did not show any significant increase of these serum enzymes. Results also show that the yogurt administration to hyperlipidemic / hypercholesterolemic rats induced a significant decrease in the total serum cholesterol, VLDL-cholesterol, albumin, LDL-cholesterol and triglycerides, and a significant increase of HDL-cholesterol concentration in sera of test groups. In conclusion, our data support the consumption of potential probiotic yogurt to decrease serum cholesterol and also confirm the persistence of probiotic effects after these yogurts processing techniques. 19 Eurydice Flore Tiepma Ngongang et al.: Effects of Probiotic Bacteria from Yogurt on Enzyme and Serum Cholesterol Levels of Experimentally Induced Hyperlipidemic Wistar Albino Rats
Asian Journal of Research in Biochemistry
Cholesterol-Lowering Effects of Lactobacilli and Bifidobacteria Probiotics in vitro and in vivo2018 •
Two lactobacilli strains; Lactobacillus acidophilus ATCC 20079 and Lactobacillus plantarum ATCC 20179 and two bifidobacteria strains; Bifidobacterium bifidum GSGG 5286 and Bifidobacterium longum ATCC 15707 were studied their abilities to reduce the cholesterol content in vitro. It was investigated that the in vivo cholesterol-lowering effect of L. plantarum ATCC 20179, B. bifidum GSGG 5286 and mixture of both probiotics (L. plantarum ATCC20179 and B. bifidum GSGG5286) on hyperlipidaemic rats for 8 weeks. All lactobacilli and bifidobacteria strains assimilate the cholesterol content in laboratory media. It was observed the highest assimilation of cholesterol was in L. plantarum ATCC 20179 and B. bifidum GSGG 5286 strains. In vivo, L. plantarum ATCC 20179 group was more effective in improving serum lipid profile levels [total cholesterol (TC), triglycerides (TG), low density lipoprotein – cholesterol (LDL-C), high density lipoprotein – cholesterol (HDL-C), very low ...
International Dairy Journal
The hypocholesterolaemic effect of milk yoghurt and soy-yoghurt containing bifidobacteria in rats fed on a cholesterol-enriched diet2005 •
Nutrition, Metabolism and Cardiovascular Diseases
The impact of probiotic yogurt consumption on lipid profiles in subjects with mild to moderate hypercholesterolemia: A systematic review and meta-analysis of randomized controlled trialsBACKGROUND: Barley, which is rich in-glucans, is known to exhibit hypocholesterolemic effect. OBJECTIVE: The study aimed to investigate the hypocholesterolemic effect of yogurt containing barley-glucan (BBG) and probiotic bacteria in rats fed on a cholesterol-enriched diet. METHODS: The methodology was based on adding of 0.75% BBG to skim milk (SM) powder. Four treatments of yogurt were formulated, wherein the first treatment was produced from SM without the addition of BBG and fermented by yogurts starter (YS). The second treatment was produced from SM with the addition of 0.75% BBG, and fermented by YS. The third treatment was produced from SM without the addition of 0.75% BBG, and fermented by Bifidobacterium lactis plus Lactobacillus acidophilus. The fourth treatment was produced from SM with addition of 0.75% BBG, and fermented by Bifidobacterium lactis plus Lactobacillus acidophilus. All formulations were evaluated for their effect on plasma lipids, liver lipids, lipid peroxidation, and the fecal excretion of bile acids in rats. RESULTS: The results indicated that yogurt containing probiotic bacteria and BBG was more effective in lowering of plasma and liver cholesterol levels than other treatments. The fecal excretions of bile acids and lipid peroxidation were markedly promoted in yogurt formulated with BBG and probiotic bacteria compared with the positive control group. The results showed an inverse relationship between the fecal excretions of bile acids and the levels of total cholesterol in the plasma from rats fed on a high-cholesterol diet. CONCLUSION: The inclusion of BBG and probiotic bacteria in the diet of rats fed on high-cholesterol diet had health-promoting impacts on the levels of plasma and liver lipids. Yogurt with Bifidobacterium plus L. acidophilus and supplemented with BBG were effective in lowering the levels of cholesterol in plasma and liver lipids, while the excretion of bile acids in the feces was enhanced. These hypocholesterolemic effects of yogurt preparations containing BBG and probiotic bacteria could create an effective and economic contribution in treating hypercholesterolaemia.
Lipids in Health and Disease
Influence of a probiotic soy product on fecal microbiota and its association with cardiovascular risk factors in an animal model2011 •
Romanian Journal of Diabetes Nutrition and Metabolic Diseases
Short-Term Consumption of Probiotic Yogurt Improved HDL-C of Type 2 Diabetes Mellitus Patients: A Double-Blind Randomized Controlled TrialBackground and aims: Cardiovascular disease is the main complication and cause of morbidity and mortality in type 2 diabetes mellitus (T2DM) patients. The main cause of complication in T2DM is oxidative stress caused by insulin resistance, hence it can increase lipid profiles (cholesterol, LDL, and triglycerides) which exacerbates endothelial dysfunction. Among various functional foods with antioxidant effects, probiotic foods have been reported to suppress oxidative stress, and also improve the fasting blood glucose (FBG) and lipid profile in patients with T2DM. The aim of this clinical trial is to study the effects of probiotics and conventional yogurt on FBG and lipid profile in patients with T2DM. Material and method: Thirty-eight patients with T2DM, aged 30 to 60 years old, were assigned to two groups in this randomized, doubleblind, controlled clinical trial. The subjects in the intervention group consumed 100 ml/day probiotic yogurt containing Lactobacillus acidophilus La-5 a...
Scientia Pharmaceutica
A Mini-Review of Human Studies on Cholesterol-Lowering Properties of Probiotics2017 •
Some probiotics have hypocholesterolemic effects in animal studies, which are mediated, in part, by increases in fecal short chain fatty acids (SCFAs). Clinical trials of probiotics on lipids/lipoproteins are inconsistent. We examined the effects of Bifidobacterium animalis subsp. lactis BB-12(®) (BB-12(®)) (3.16 × 10(9) CFUs/day) on lipids and lipoproteins and fecal excretion of SCFAs in healthy adults. In a randomized, partially blinded, 4-period, crossover study, 30 adults (11 men, 19 women) aged 18-40 years were randomly assigned to: 1) yogurt smoothie with no BB-12(®) (YS), 2) yogurt smoothie with BB-12(®) added pre-fermentation (PRE), 3) yogurt smoothie with BB-12(®) added post-fermentation (POST), 4) BB-12(®) containing capsule (CAP). We measured serum lipids/lipoproteins, glucose, insulin, C-reactive protein (CRP), and fecal SCFAs at baseline and after each treatment period. Total cholesterol (TC), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), and triglycerides (TGs) did...
2024 •
Journal of Veterinary Medical Science
Ocular disease caused by the trematode Philophthalmus lachrymosus in free-living kelp gulls (Larus dominicanus) of BrazilJournal of Visualized Experiments
Laser Microdissection for Species-Agnostic Single-Tissue Applications2022 •
Journal of Cognitive Sciences and Human Development
Parenting Styles and Academic Achievement among Malaysian Students: Mediating Role of Parental Involvement2022 •
2019 •
Physics Procedia
Polarization Analysis Equipment in SANS-J-II: Study of Polymer Electrolyte Membrane for Fuel Cell2013 •
Veterinaria Noticias
Características Histológicas De Nervos Espinhais De MamíferosEuropean Journal of Cancer
In situ breast cancer: Incidence trend and organised screening programmes in Italy2005 •
2015 •
Japanese Journal of Applied Physics
Quantum-efficiency Dependence of the Spin Polarization of Photoemission from a GaAs–AlGaAs Superlattice1997 •