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Oncology & Cancer news
Oncology & Cancer
Investigators identify potential new targets to overcome treatment resistance in aggressive breast cancer
Researchers with the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborators have shown that immature natural killer (NK) cells are present in patients with triple-negative ...
7 hours ago
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Oncology & Cancer
Serious consequences identified for young survivors of brain cancer
From neurological problems to hearing loss and infertility, survivors of medulloblastoma, an aggressive form of brain cancer, are left with severe physical and cognitive impairments and have an overall mortality rate 21 times ...
1 hour ago
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Cancer that spreads to the lung maneuvers to avoid being attacked by 'killer' T cells
Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.
11 hours ago
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CPEB4 protein is essential for maintaining the antitumor function of T lymphocytes, reveals study
T lymphocytes are components of the immune system that are located in the tumor environment. They serve to identify and remove tumor cells. In order to perform this function, they must produce a large amount of secreted proteins, ...
1 hour ago
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Certain exosomes found to inhibit malignant melanoma growth, providing important prognostic marker
Cancer-associated fibroblasts (CAFs) are key factors in the tumor microenvironment, which have been implicated in cancer cell progression. It has also been reported that vesicles called exosomes produced by these CAFs play ...
2 hours ago
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ENZAMET shows promise as prostate cancer treatment
A new drug combination for men with advanced prostate cancer has shown sustained increase in survival rates.
11 hours ago
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Fibroblast inhibitors assist anti-cancer drugs to suppress cancer growth
Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body. It is believed that cancerous tumors can recruit nearby fibroblasts and use them to promote ...
4 hours ago
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A targeted method to combat cancer
By analyzing tumors in unprecedented depth, the Tumor Profiler project represents an important step along the road toward personalized cancer treatments. And the team have already recorded initial successes: In a study focusing ...
5 hours ago
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Combination treatment shows significant reduction in disease growth in patients with advanced endometrial cancer
In a study published in the March 27, 2023, online edition of the New England Journal of Medicine, researchers at the University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health found ...
22 hours ago
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New program shows promise in reducing financial burden of cancer care
The rising cost of cancer care puts patients and their caregivers at increased risk of experiencing financial toxicity, a term used to describe financial hardship caused by out-of-pocket treatment costs.
22 hours ago
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Researchers discover two-pronged approach to stimulate STING antitumor activity
Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy. Moffitt Cancer Center ...
Mar 27, 2023
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Study finds diverse differences in microbes in breast tumors from women of different races
The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by ...
Mar 27, 2023
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Atezolizumab as a primer for chemoradiation is promising for women with locally advanced cervical cancer
Locally advanced cervical cancer remains an area of high therapeutic need, with recent trials failing to demonstrate evidence of benefit from adjuvant chemotherapy or immune checkpoint blockade administered concurrent with ...
Mar 27, 2023
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Positive results for combination of ribociclib and letrozole in patients with recurrent low-grade serous ovarian cancer
The GOG Foundation, Inc. (GOG) announced positive results from an investigator-initiated phase II trial, sponsored by the GOG, investigating the combination of ribociclib and letrozole in patients with recurrent low-grade ...
Mar 27, 2023
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Study identifies two promising molecular targets for drug development in recurrent and metastatic cervical cancer
NRG Oncology GOG-0240 is the phase 3 randomized trial that demonstrated that the incorporation of bevacizumab with chemotherapy resulted in a statistically significant and clinically meaningful survival benefit for women ...
Mar 27, 2023
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Clinical study: Treatment improves outcomes for women with locally advanced vulvar cancer
Results from the NRG Oncology Phase II NRG-GOG-0279 clinical study indicate that women with locally advanced squamous cell carcinoma of the vulva who received gemcitabine concurrently with cisplatin and intensity-modulated ...
Mar 27, 2023
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Study establishes link between wound fibroblasts and cancer-associated fibroblasts
A Matrix Biology paper by the Werner group (IMHS) shows how wound healing gene expression signatures are expressed in tumors and can be used to predict cancer outcome. The paper establishes a functional link between wound ...
Mar 27, 2023
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All hormonal contraceptives increase breast cancer risk: Study
All hormonal contraceptives carry a slightly increased risk of breast cancer, including the increasingly popular progestogen-only pills, according to a study published on Tuesday.
Mar 25, 2023
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Time of day matters when it comes to cancer diagnosis and treatment, says metastasis study
Your circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review paper published in the journal Trends in Cell Biology, researchers discuss the ...
Mar 24, 2023
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Study shows how cancer gene tricks immune cells
Cancer-associated genes called oncogenes are well known to stimulate cell growth and division—causing tumors to balloon and spread. But now, researchers at the Stanford School of Medicine and Sarafan ChEM-H have found that ...
Mar 24, 2023
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