Immunotherapy has transformed cancer care. In advanced melanoma, for example, the most fatal form of skin cancer, the five-year survival rate has risen from less than 10% to more than 50% since immunotherapy was introduced ...
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An international study led by researchers from the Infection Biology Laboratory at the UPF Department of Medicine and Life Sciences (MELIS) establishes that one type of dendritic cell is crucial for the success of immunotherapeutic ...
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Many patients with the autoimmune disease ANCA-associated vasculitis (AAV) suffer a high risk of disease relapse despite treatment. Karolinska Institutet researchers have now identified T cells that contribute to the destruction ...
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University of Virginia Health neuroscientists have discovered a potential way to disrupt the chronic inflammation responsible for multiple sclerosis.
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Researchers from Japan have found that white blood cells, known as B lymphocytes, have a pivotal role in promoting an emergent response to stimulate the in-demand production of innate immune cells during an infection.
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In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst—the method white blood cells known as neutrophils use to kill invading pathogens. The study is an important first ...
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Sensory neurons pick up information from our senses and relay it to the rest of the nervous system. But this is not their only mission. In a new study published in the journal Current Biology, Claire Wyart at the Paris Brain ...
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Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune ...
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Even though the COVID-19 public health emergency classification will expire this spring, the lingering effects of the pandemic remain. A constant puzzle to solve since the first year of the pandemic has been "long COVID," ...
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Contrary to the widely shared popular belief, the primary purpose of current vaccines against COVID-19 is solely to protect against serious forms of the disease in order to prevent the risk of hospitalizations and death… ...
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White blood cells (WBCs), or leukocytes (also spelled "leucocytes"), are cells of the immune system defending the body against both infectious disease and foreign materials. Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a hematopoietic stem cell. Leukocytes are found throughout the body, including the blood and lymphatic system.
The number of leukocytes in the blood is often an indicator of disease. There are normally between 4×109 and 1.1×1010 white blood cells in a litre of blood, making up approximately 1% of blood in a healthy adult. An increase in the number of leukocytes over the upper limits is called leukocytosis, and in leukopenia, this number is much lower than the lower limit. The physical properties of leukocytes, such as volume, conductivity, and granularity, may change due to activation, the presence of immature cells, or the presence of malignant leukocytes in leukemia.
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