Researchers use a new approach to hit an 'undruggable' target
The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category. Now, University of Michigan Rogel Cancer Center researchers have found success ...
23 hours ago
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No radiotherapy an option for older breast cancer patients, study shows
Radiotherapy does not improve survival rates in older patients with early breast cancer, new research suggests.
20 hours ago
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New insights into how blood pressure drug may benefit patients with locally advanced pancreatic cancer
Pancreatic cancer is highly lethal, and surgical removal of tumor tissue is currently the only potential cure for most patients. Once the cancer has spread beyond the pancreas, treatment options are limited.
23 hours ago
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Scrapping England's cancer plan is 'a catastrophic decision that will cost lives' warn experts
The UK government's proposal to roll England's long term plan for cancer into one strategy covering all major conditions, such as cardiovascular disease, chronic respiratory disease, dementia, mental health conditions, and ...
18 hours ago
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Financial toxicity from breast cancer treatment is common
Worldwide, breast cancer treatment is associated with substantial financial toxicity, according to a systematic review and meta-analysis published online Feb. 8 in JAMA Network Open.
23 hours ago
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Study finds education and navigation increase cancer genetic counseling and/or testing
Genetic counseling and genetic testing for mutations in certain genes such as BRCA1 and BRCA2 genes—can help people understand their risk of certain types of cancer that can run in families, and improve outcomes through ...
Feb 15, 2023
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Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer
Patients with resectable non–small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes, according to results ...
Feb 15, 2023
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Study finds Black patients wait longer for uterine cancer testing, diagnosis
Early diagnosis of uterine cancer is known to improve a patient's chances for survival, but previous research has found that Black patients are less likely to receive early diagnoses than people of other racial and ethnic ...
Feb 15, 2023
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Scientists identify protein crucial to tumor cells' metabolism and immune evasion
Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune ...
Feb 14, 2023
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New insights into the drivers of glioma-related epilepsy
Glioma is one of the most aggressive malignant primary brain tumors. A common feature of glioma is the presence of localized, intermittent seizures referred to as glioma-related epilepsy, which is known to promote tumor growth. ...
Feb 14, 2023
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Breast cancer risk models may incorrectly classify many women
Breast cancer risk estimates for individual women vary substantially depending on which risk assessment model is used, and women are likely receiving vastly different recommendations depending on the model used and the cutoff ...
Feb 14, 2023
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AI with infrared imaging enables precise colon cancer diagnostics
The immense progress in the field of therapy options over the past years has significantly improved the chances of cure for patients with colon cancer. However, these new approaches, such as immunotherapies, require precise ...
Feb 14, 2023
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Night work may increase the risk of aggressive prostate cancer in offshore petroleum workers
Many employees in the offshore sector work night shifts. This may make them more susceptible to aggressive prostate cancer than if they only worked during the day.
Feb 14, 2023
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New machine learning model improves prediction of prostate cancer recurrence
Predicting the course of prostate cancer is challenging because only a fraction of prostate cancer patients experience recurrence after radical prostatectomy or radiation therapy. Yet, prostate cancer remains one of the most ...
Feb 14, 2023
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Analysis of cancer treatment reveals need for standardized methods to measure waiting times
A review of associations between cancer waiting times and treatment outcomes highlights inconsistencies in reporting that make it hard to draw firm conclusions, according to a report published today in eLife.
Feb 14, 2023
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Novel prognostic index to predict survival outcomes in gastric cancer patients
A new research paper titled "Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer" has been published in Oncotarget.
Feb 14, 2023
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Quitting smoking tied to better survival in head, neck squamous cell carcinoma
Smoking cessation for >10 years is significantly associated with reduced overall mortality and head and neck squamous cell carcinoma (HNSCC)-specific mortality, according to a study published online Jan. 18 in Cancer.
Feb 14, 2023
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Conundrum solved over HPV link with head and neck cancer
A major international trial published in The Lancet Oncology has looked at studies from 13 head and neck cancer centers from nine countries around the world. Using the data of 7,895 patients, a research team has found that ...
Feb 13, 2023
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