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Medications
Small molecule drug reverses ADAR1-induced cancer stem cell cloning capacity
Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant ...
16 minutes ago
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High drug prices are not justified by industry's research and development spending, argue experts
High drug prices are not justified by industry's spending on research and development (R&D;), argue experts in The BMJ today.
18 hours ago
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Researchers use a new approach to hit an 'undruggable' target
The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category. Now, University of Michigan Rogel Cancer Center researchers have found success ...
23 hours ago
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/researchers-use-a-new.jpg)
Drug linked to lower risk of dementia in people with diabetes
People with diabetes are twice as likely to develop dementia as those without the disease. In a new study, people with newly diagnosed type 2 diabetes who took the diabetes drug pioglitazone were less likely to later develop ...
20 hours ago
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/pill-1.jpg)
New insights into how blood pressure drug may benefit patients with locally advanced pancreatic cancer
Pancreatic cancer is highly lethal, and surgical removal of tumor tissue is currently the only potential cure for most patients. Once the cancer has spread beyond the pancreas, treatment options are limited.
23 hours ago
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2022/cancer.jpg)
'Angong Niuhuang Wan' could reduce the side effects of thrombolytic therapy and extend therapeutic window for stroke
A research team led by Professor Shen Jiangang from the School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) reveals that Angong Niuhuang Wan (AGNHW), a classical Chinese medicinal formula, ...
21 hours ago
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/angong-niuhuang-wan-co.jpg)
Research explores cause of differences in psychostimulant duration and intensity of effect
Psychostimulants interacting with the dopamine transporter are found in the therapy of neuro-psychiatric disorders, such as ADHD or depression, as well as on the illicit drug market. In order to better understand their exact ...
Feb 15, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/cause-of-differences-i.jpg)
Tackling skin inflammation with vitamin D
High-dose oral vitamin D reduced skin inflammation and increased immunoprotection in patients with chemical-induced skin rashes, according to findings from a recent Northwestern Medicine clinical trial published in JCI Insight.
Feb 15, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/tackling-skin-inflamma.jpg)
Migraine drug shows promise in treatment of acute kidney injury
The drug lasmiditan, which is used to treat migraines, shows promise as a possible treatment for acute kidney injury, according to a new study from the University of Arizona. The findings are published ahead of print in the ...
Feb 15, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/migraine-drug-shows-pr.jpg)
FDA panel considers making opioid antidote drug available without prescription
A nasal spray that can reverse an opioid overdose may become available for easier over-the-counter purchase.
Feb 15, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/fda-panel-considers-ma.jpg)
Researchers endorse widespread naloxone over the counter to prevent drug overdose deaths
In 2021, 100,306 Americans died from drug overdoses—a 28.5 percent increase from the prior year—with 75,673 attributed to opioids. Synthetic opioids, primarily fentanyl and natural and semi-synthetic opioids, are major ...
Feb 15, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2019/2-overdose.jpg)
Rapid screening test predicts effectiveness of steroid injections for neck pain
Researchers from Johns Hopkins Medicine and several other institutions say they have developed a quick clinical test that predicts which people with neck pain are more likely to benefit from epidural steroid injections, which ...
Feb 15, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2021/neckpain.jpg)
Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer
Patients with resectable non–small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes, according to results ...
Feb 15, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/neoadjuvant-nivolumab.jpg)
Initiation of opioids not recommended for chronic pain
In a synopsis of the latest U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) clinical practice guideline, published online Feb. 14 in the Annals of Internal Medicine, updated recommendations are ...
Feb 14, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/initiation-of-opioids.jpg)
0.05 percent atropine eye drops result in lower incidence of myopia
Nightly use of 0.05 percent atropine eye drops compared with placebo results in a significantly lower incidence of myopia and a lower percentage of patients with fast myopic shift at two years among children aged 4 to 9 years ...
Feb 14, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/005-percent-atropine-e.jpg)
Study shows improved walking distance for spinal muscular atrophy patients after nusinersen treatment
A positive effect of nusinersen treatment on motor function in ambulant pediatric and adult spinal muscular atrophy (SMA) patients during a 38-month period has been demonstrated by an analysis of data from the SMArtCARE registry. ...
Feb 14, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/spinal-muscular-atroph.jpg)
1 in 10 new drugs don't achieve their main goals despite FDA approval, study finds
One in 10 new drugs were cleared by federal drug regulators in recent years based on studies that didn't achieve their main goals, a new study shows.
Feb 14, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2022/drug.jpg)
Not allergic to penicillin after all? Your pharmacy may not know
When testing determines that a patient who was thought to be allergic to penicillin actually is not, the warning is expected to be removed from their charts and pharmacy records.
Feb 14, 2023
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![](https://web.archive.org/web/20230216181949/https://scx1.b-cdn.net/csz/news/175u/2023/not-allergic-to-penici.jpg)
Drug shown to alleviate autism-associated behavior in mice
The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for ...
Feb 13, 2023
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