[HTML][HTML] The hallmarks of aging

C López-Otín, MA Blasco, L Partridge, M Serrano… - Cell, 2013 - Elsevier
Aging is characterized by a progressive loss of physiological integrity, leading to impaired
function and increased vulnerability to death. This deterioration is the primary risk factor for
major human pathologies, including cancer, diabetes, cardiovascular disorders, and
neurodegenerative diseases. Aging research has experienced an unprecedented advance
over recent years, particularly with the discovery that the rate of aging is controlled, at least
to some extent, by genetic pathways and biochemical processes conserved in evolution …