chancre (n.)

Old English cancer "spreading sore, malignant tumor" (also canceradl), from Latin cancer "a crab," later, "malignant tumor," from Greek karkinos, which, like the Modern English word, has three meanings: a crab, a tumor, and the zodiac constellation represented by a crab. This is from PIE *karkro-, a reduplicated form of the root *kar- "hard."

Greek physicians Hippocrates and Galen, among others, noted similarity of crabs to some tumors with swollen veins. The Old English word was displaced by French-influenced doublet canker but was reintroduced in the modern medical sense c. 1600. In reference to the zodiac sign, it is attested from late Old English; the meaning "person born under the zodiac sign of Cancer" is from 1894. The sun being in Cancer at the summer solstice, the constellation had association in Latin writers with the south and with summer heat. Cancer stick "cigarette" is a slang phrase attested from 1959.

"resembling a chancre," 1868, from chancre + -oid. Earlier as a noun, a kind of genital ulcer (1861).

also *ker-, Proto-Indo-European root meaning "hard."

It forms all or part of: -ard; Bernard; cancer; canker; carcinogen; carcinoma; careen; chancre; -cracy; Gerard; hard; hardly; hardy; Leonard; Richard; standard.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit karkatah "crab," karkarah "hard;" Greek kratos "strength," kratys "strong;" "hard;" Old English heard, German hart "solid and firm, not soft."