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Australian Adverse Drug Reactions Bulletin
1995-2009
The Australian Adverse Drug Reactions Bulletin was produced six times a year by the Adverse Drug Reactions Advisory Committee (ACSOM), which was replaced by the Advisory Committee on the Safety of Medicines (ACSOM) in January 2010.
The Bulletin was first published in 1982. The following issues date from 1995 (when the electronic version was introduced) to 2009.
The Bulletin has since been replaced by the Medicines Safety Update, which is also published six times a year, and appears in each issue of Australian Prescriber.
2009
- Australian Adverse Drug Reactions Bulletin, Vol 28, No 6
Drugs of current interest; ADRAC comes to an end after 39 years; The last Bulletin; Thank you to our readers; A tribute to ADRAC from the TGA; Consider applying to become an Expert Adviser to the TGA - Australian Adverse Drug Reactions Bulletin, Vol 28, No 5
Drugs of current interest; TGA approves H1N1 influenza virus vaccine; The long and the short of movement disorders with metoclopramide; Washout or taper when switching antidepressants - Australian Adverse Drug Reactions Bulletin, Vol 28, No 4
Drugs of current interest; Serotonin syndrome with duloxetine; Fixed drug eruptions; Is it leflunomide lung?; Isotretinoin and acquired hearing impairment - Australian Adverse Drug Reactions Bulletin, Vol 28, No 3
Drugs of current interest; Drug-associated macular oedema - latanoprost and rosiglitazone; Drug-induced lupus erythematosus: An emerging association with TNF inhibitors; Metformin, dehydration and lactic acidosis - Australian Adverse Drug Reactions Bulletin, Vol 28, No 2
Drugs of current interest; Severe adverse reactions with intravenous immunoglobulin; Serious reaction reminders: sodium valproate and fetal malformations; Serious reaction reminders: cefaclor and serum sickness-like reactions in children; Lignocaine with chlorhexidine gel and anaphylaxis - Australian Adverse Drug Reactions Bulletin, Vol 28, No 1
Drugs of current interest; Adverse reactions with botulinum toxin A (Botox, Dysport); Proton pump inhibitors and possible fracture risk
2008
- Australian Adverse Drug Reactions Bulletin, Vol 27, No 6
Drugs of current interest; Varenicline: The Australian experience so far; Modafinil: adverse skin and psychiatric reactions; Risks of fulminant liver failure when stopping drugs for the management of hepatitis B; Thank you for your reports - Australian Adverse Drug Reactions Bulletin, Vol 27, No 5
Drugs of current interest; Fatal interactions and reactions with colchicine: beware CYP3A4 inhibitors; Fluoroquinolone antibiotics and tendon disorders: still a problem; Drug-induced hyponatraemia - Australian Adverse Drug Reactions Bulletin, Vol 27, No 4
New 'Blue card' reporting form for ADRs; High-dose vitamin B6 may cause peripheral neuropathy; Desmopressin and hyponatraemia; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 27, No 3
Severe skin reactions and venous thromboembolism with strontium ranelate (Protos); Statins and muscle disorders - be careful with the dose; Hepatic toxicity with nitrofurantoin; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 27, No 2
Nicorandil-associated ulceration; Withdrawal of lumiracoxib in Australia; Topiramate and other drugs causing glaucoma; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 27, No 1
MRI scans with gadolinium-containing contrast agents and the risk of NSF - caution in patients with renal impairment; Hepatic reactions with terbinafine; Interaction between glucosamine and warfarin; Drugs of current interest
2007
- Australian Adverse Drug Reactions Bulletin, Vol 26, No 6
Emerging cardiovascular concerns with rosiglitazone; Erythropoietins: aim for lower haemoglobin levels; Reports of hypersensitivity reactions to pregabalin; Transdermal medications - look for the patch; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 26, No 5
Thiazolidinediones and reduced bone density; Renal impairment with zoledronic acid; Dangers associated with chronic ingestion of colloidal silver; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 26, No 4
Rituximab and progressive multifocal leukoencephalopathy; Implanon: interactions and failure of contraception; Atypical antipsychotic agents and extrapyramidal side effects; Subscribe to the Bulletin on-line; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 26, No 3
Clozapine and myocarditis; Mirtazapine and blood dyscrasias; Black cohosh and liver toxicity - an update; ADRAC celebrates 300 meetings; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 26, No 2
Aripiprazole and neuroleptic malignant syndrome; Varicella vaccine experience in Australia; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 26, No 1
Traditional Indian (Ayurvedic) and Chinese medicines associated with heavy metal poisoning; Zolpidem and bizarre sleep related effects; Increased risk of fractures associated with enzyme-inducing antiepileptic medicines; Drugs of current interest
2006
- Australian Adverse Drug Reactions Bulletin, Vol 25, No 6
Drug induced pancreatitis; Leflunomide and interstitial lung disease; Tumour necrosis factor alpha inhibitors; Subscribe to the Bulletin on-line; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 25, No 5
Beware the triple whammy!; Leflunomide and peripheral neuropathy; Ezetimibe and depression - A possible signal; Subscribe to the Bulletin on-line; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 25, No 4
Osteonecrosis of the jaw with bisphosphonates; Dose reduction of LMWH (enoxaparin) in chronic kidney disease; Life threatening blood dyscrasias with oral terbinafine; Update and clarification; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 25, No 3
Problems with colloids in fluid resuscitation; Reactivation of hepatitis B virus following cytotoxic or immunosuppressant therapy; Sibutramine - Four years experience; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 25, No 2
Hepatotoxicity with black cohosh; Medical Alert devices; Interactions with macrolides; Changes to ADRAC membership; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 25, No 1
Deaths with galantamine in mild cognitive impairment studies; Fluoroquinolone antibiotics...Interactions with warfarin; Fluoroquinolone antibiotics...Remember tendon disorders; Ergot derivatives and fibrotic reactions; Drugs of current interest
2005
- Australian Adverse Drug Reactions Bulletin, Vol 24, No 6
Medicines and QT prolongation; Skin reactions with glucosamine; Warfarin-induced skin necrosis; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 24, No 5
Inadvertent paracetamol overdose; Please report paediatric adverse reactions; Screening guidelines for women exposed to DES in utero; Retirement of Dr John McEwen; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 24, No 4
Suicidality with SSRIs: adults and children; Ezetimibe and muscle disorders; Pathological gambling with cabergoline; Reporting problems with products other than medicines; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 24, No 3
Acne, isotretinoin and suicidality; Genitourinary symptoms with reboxetine; The multiple toxicities of amiodarone; Antidepressants in children and adolescents; Pimecrolimus, skin cancer and lymphoma; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 24, No 2
Statins and peripheral neuropathy; Avascular necrosis with interferon alfa-2b in CML; Angioedema - still a problem with ACE inhibitors; Evidence-based medicine: pitfalls of overlooking safety; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 24, No 1
Adverse reactions to complementary medicines; Avoiding fetal abnormalities with isotretinoin; Bisphosphonates and osteonecrosis of the jaw; Statins contraindicated in pregnancy; Drugs of current interest
2004
- Australian Adverse Drug Reactions Bulletin, Vol 23, No 6
Use of SSRI antidepressants in children and adolescents; Cardiovascular risk with the selective COX-2 inhibitors; Propofol: danger of prolonged and high infusion rates in ICU; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 23, No 5
Australian experience with pneumococcal conjugate vaccine; Warnings for high dose tricyclic antidepressants; Terbinafine and blood dyscrasias; Cholinesterase inhibitors and cardiac arrhythmias; Quinine indications - cramps deleted; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 23, No 4
Cardiac valvulopathy with pergolide; Clopidogrel - haemorrhage and haematological disorders; Pulmonary toxicity with long-term nitrofurantoin; Tramadol-warfarin interaction; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 23, No 3
The legacy of diethylstilboestrol (DES) from the 50s and 60s; Parecoxib - one shot only; Corticosteroids should be used with long-acting β2-agonists; Atypical antipsychotics and hyperglycaemia; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 23, No 2
The risks and benefits of HRT; Macrolides and warfarin interaction; Bisphosphonates and ocular inflammation; SSRI antidepressants in children and adolescents; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 23, No 1
Risk factors for myopathy and rhabdomyolysis with the statins; High dose cyproterone and hepatotoxicity; Serotonin syndrome; Drugs of current interest
2003
- Australian Adverse Drug Reactions Bulletin, Vol 22, No 6
Meningococcal C vaccine: early experience is reassuring; Harmful interactions; Post-partum NSAIDs may cause hypertension; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 22, No 5
Rofecoxib, celecoxib and cardiovascular risk; Convulsions and blood dyscrasias with mirtazapine; Anti-epileptic drugs, pregnancy and fetal malformations; Hormone replacement therapy; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 22, No 4
Maternal SSRI use and neonatal effects; ACE inhibitor, diuretic and NSAID: a dangerous combination; Serious gastrointestinal effects with celecoxib and rofecoxib; Travacalm - your reports make a difference!; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 22, No 3
Hyponatraemia with SSRIs; Pregnancy despite depot medroxyprogesterone; Hepatic reactions with minocycline; Implanon and vaginal bleeding; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 22, No 2
Fluticasone and adrenal crisis; The glitazones - early experience; Interstitial nephritis with the proton pump inhibitors; Interactions with grapefruit juice - amendment; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 22, No 1
Tramadol - four years' experience; Minocycline and not so benign intracranial hypertension; Acute neuropsychiatric events with celecoxib and rofecoxib; Linezolid and peripheral neuropathy; Kava; Drugs of current interest
2002
- Australian Adverse Drug Reactions Bulletin, Vol 21, No 4
Interactions with grapefruit juice; Miconazole oral gel elevates INR - a reminder; Fluoroquinolones and tendon disorders; Online reporting of adverse reactions - coming soon; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 21, No 3
Patent blue V and anaphylaxis; Quinine and profound thrombocytopenia; Indapamide and hyponatraemia; Epoetin alfa and pure red cell aplasia; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 21, No 2
Sildenafil - three years experience; Haemorrhagic cystitis with ticarcillin in cystic fibrosis patients; Venous thromboembolism with third generation oral contraceptives and cyproterone; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 21, No 1
Electrolyte disturbances with sodium picosulfate bowel cleansing products; Amiodarone and pulmonary toxicity; Interaction of rofecoxib with warfarin; Seeing things with zolpidem; Drugs of current interest
2001
- Australian Adverse Drug Reactions Bulletin, Vol 20, No 4
Tramadol and serotonin syndrome; Raloxifene and thromboembolic events; Your reports at work - drug safety in Australia - Australian Adverse Drug Reactions Bulletin, Vol 20, No 3
Extensive limb swelling and DTPa booster doses; P-glycoprotein - another way for drugs to interact; Nitrofurantoin and peripheral neuropathy; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 20, No 2
Update on bupropion (Zyban SR); Leflunomide: serious hepatic, blood, skin and respiratory reactions; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 20, No 1
Interaction of celecoxib and warfarin; Metformin and lactic acidosis - a reminder; Cerivastatin and rhabdomyolysis - avoid gemfibrozil; SSRIs and increased intraocular pressure; Warning: potential for confusion with Humalog; Drugs of current interest
2000
- Australian Adverse Drug Reactions Bulletin, Vol 19, No 4
Restriction of indications for cisapride; Interaction between ergotamine and erythromycin; Methysergide and cardiac valvulopathy; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 19, No 3
Drug interactions and adverse drug reactions; Cyclosporin and St John's wort: CYP3A4; Simvastatin and nefazodone: CYP3A4; Perhexiline and paroxetine: CYP2D6; Fluvoxamine and warfarin: CYP1A2; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 19, No 2
Celecoxib: early Australian reporting experience; Zanamivir and respiratory effects; Alert! Interactions with St John's wort; Valaciclovir: renal impairment and neuropsychiatric reactions; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 19, No 1
Drug-induced nightmares; Take care with vitamin K; Problems with caffeine; Allopurinol azathioprine interaction - a reminder; New drug update - serious adverse reactions with leflunomide; Drugs of current interest
1999
- Australian Adverse Drug Reactions Bulletin, Vol 18, No 4
Methotrexate misadventures; Constipation - it can be severe with clozapine; TTP with ticlopidine Thanks for your reports; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 18, No 3
Tendinitis and tendon rupture with fluoroquinolones; Olanzapine: neutropenia, convulsions and NMS; A gut feeling for alendronate; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 18, No 2
Depression with interferon; Coumadin and Marevan are not interchangeable; Drug-induced gingival overgrowth; A comparison of dicloxacillin with flucloxacillin; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 18, No 1
Angiotensin II receptor antagonists ? new drugs ...; Allergic reactions with echinacea; Update on visual field constriction with vigabatrin; Withdrawal of tolcapone; Drugs of current interest
1998
- Australian Adverse Drug Reactions Bulletin, Vol 17, No 4
Nefazodone ? looks like an SSRI, but ...; Ondansetron and chest pain; Viagra is here!; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 17, No 3
Bruising and bleeding with SSRIs; Worldwide withdrawal of mibefradil; Drugs that make you forget; Depression with isotretinoin; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 17, No 2
Ticlopidine update; Protease inhibitors; Methotrexate - name the day; Interaction between miconazole oral gel and warfarin; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 17, No 1
Paradoxical reactions with midazolam in children; Venlafaxine: not just an SSRI?; Depression - could it be the drug?; Withdrawal of fenfluramine and dexfenfluramine; Drugs of current interest
1997
- Australian Adverse Drug Reactions Bulletin, Vol 16, No 4
SSRIs and neonatal disorders ......; Boxed warnings; Laboratory monitoring with calcitriol - an update; Fatal outcomes after sumatriptan; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 16, No 3
Alendronate oesophagitis - are precautions effective?; Pethidine and convulsions; Drug-induced gynaecomastia; Visual field defects with vigabatrin; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 16, No 2
Kombucha tea; Clozapine induced neuroleptic malignant syndrome; The Achilles heel of fluoroquinolones; Paraesthesia with NSAIDS; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 16, No 1
Electrolyte disturbances with oral phosphate bowel preparations; Calcitriol and hypercalcaemia; Fluvastatin and muscle disorders - a class effect; Lamotrigine and severe skin reactions; Drugs of current interest
1996
- Australian Adverse Drug Reactions Bulletin, Vol 15, No 4
Minocycline and ...... the liver, the CNS, the skin; Vitamin A and birth defects; Angioedema and ACE inhibitors; Moclobemide and hypertension is it drug-induced?; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 15, No 3
Cisapride and cardiac arrhythmias; Oral acyclovir and neurological reactions; SSRIs and genitourinary disorders; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 15, No 2
Drug-induced liver disease ...; ... Antibiotics of continuing concern; Hepatitis B vaccines - musculoskeletal reactions; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 15, No 1
Quinine and haemolytic uraemic syndrome; Terbinafine - a question of taste; SSRIs and withdrawal syndrome; Possible arrhythmias due to loratadine? - More help please; Drugs of current interest
1995
- Australian Adverse Drug Reactions Bulletin, Vol 14, No 4
Nitrofurantoin and the lung; Omeprazole; Drug-induced pancreatitis; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 14, No 3
Cefaclor in the young patient: arthritis and arthralgia; Simvastatin and adverse endocrine effects in men; Lodema and the liver; Interaction of warfarin with macrolide antibiotics; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 14, No 2
Amiodarone - a reminder; Fatal lactic acidosis with metformin; Hepatic reactions to...roxithromycin...and to ranitidine; Drugs of current interest - Australian Adverse Drug Reactions Bulletin, Vol 14, No 1
Serious arrhythmias with intravenous erythromycin; Psychiatric effects of vigabatrin; Bronchospasm and NSAIDs over the counter; Drugs of current interest