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NCBI Databases

Literature

The World's largest repository of medical and scientific abstracts, full-text articles, books and reports

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

HomoloGene

Homologous genes sets for selected organisms

PopSet

Sequence sets from phylogenetic and population studies

UniGene

Clusters of expressed transcripts

Genetics

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Clusters

Sequence similarity-based protein clusters

Sparcle

Functional categorization of proteins by domain architecture

Structure

Experimentally-determined biomolecular structures

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

Probe

Sequence-based probes and primers

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

Chemicals

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioSystems

Molecular pathways with links to genes, proteins and chemicals

PubChem BioAssay

Bioactivity screening studies

PubChem Compound

Chemical information with structures, information and links

PubChem Substance

Deposited substance and chemical information

Recent blog posts

March 29, 2019

Important improvements on the genome Assembly pages

We’ve been making improvements to the NCBI genome Assembly resource. Highlights include: Links added between members of a pair of genome assemblies ...

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March 27, 2019

NCBI Computational Virology Workshop at LSU New Orleans!

Introduction to NGS Analysis in a Cloud Environment for Novice Bioinformaticians: We are pleased to announce a free workshop in New Orleans, ...

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March 26, 2019

NCBI at the ACMG meeting in Seattle next week (April 2-6, 2019)

In about a week, NCBI staff will join GeneReviews® on their home turf, Seattle, at the Annual Clinical Genetics Meeting hosted by ...

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BLAST

Basic Local Alignment Search Tool

BLAST is a tool for comparing an amino acid or nucleotide sequence to an entire sequence library, identifying regions of high sequence similarity.

More options

Video tutorial

VIDEO: NCBI Minute: Using BLAST Well

In this webinar, the NCBI BLAST team lead will show you how to be more effective with NCBI’s standalone BLAST applications. You will learn how ...

 View at YouTube